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Items: 1 to 20 of 56

1.

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines.

Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK.

Nature. 2001 Sep 20;413(6853):311-6.

PMID:
11565033
2.

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.

Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI.

Nature. 2001 Sep 20;413(6853):316-22.

PMID:
11565034
3.

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines.

Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber D, Hariharan IK.

Cell. 2002 Aug 23;110(4):467-78.

4.

Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.

Fujii Y, Yada M, Nishiyama M, Kamura T, Takahashi H, Tsunematsu R, Susaki E, Nakagawa T, Matsumoto A, Nakayama KI.

Cancer Sci. 2006 Aug;97(8):729-36.

5.

The Drosophila F box protein archipelago regulates dMyc protein levels in vivo.

Moberg KH, Mukherjee A, Veraksa A, Artavanis-Tsakonas S, Hariharan IK.

Curr Biol. 2004 Jun 8;14(11):965-74.

6.

Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer.

Kwak EL, Moberg KH, Wahrer DC, Quinn JE, Gilmore PM, Graham CA, Hariharan IK, Harkin DP, Haber DA, Bell DW.

Gynecol Oncol. 2005 Jul;98(1):124-8.

PMID:
15913747
7.

Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells.

Willmarth NE, Albertson DG, Ethier SP.

Breast Cancer Res. 2004;6(5):R531-9. Epub 2004 Jul 6.

8.

Cell cycle. Archipelago of destruction.

Schwab M, Tyers M.

Nature. 2001 Sep 20;413(6853):268-9. No abstract available.

PMID:
11565017
9.

hCDC4 gene mutations in endometrial cancer.

Spruck CH, Strohmaier H, Sangfelt O, Müller HM, Hubalek M, Müller-Holzner E, Marth C, Widschwendter M, Reed SI.

Cancer Res. 2002 Aug 15;62(16):4535-9.

10.

Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer.

Ekholm-Reed S, Spruck CH, Sangfelt O, van Drogen F, Mueller-Holzner E, Widschwendter M, Zetterberg A, Reed SI.

Cancer Res. 2004 Feb 1;64(3):795-800. Erratum in: Cancer Res. 2004 Apr 15;64(8):2939. Reed, Susanna Ekholm [corrected to Reed-Ekholm, Susanna].

11.

Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms.

van Drogen F, Sangfelt O, Malyukova A, Matskova L, Yeh E, Means AR, Reed SI.

Mol Cell. 2006 Jul 7;23(1):37-48.

12.

Cyclins in breast cancer: too much of a good thing.

Enders GH.

Breast Cancer Res. 2002;4(4):145-7. Epub 2002 Jun 7.

13.

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

Nakayama KI, Hatakeyama S, Nakayama K.

Biochem Biophys Res Commun. 2001 Apr 13;282(4):853-60. Review.

PMID:
11352628
14.

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E.

Dealy MJ, Nguyen KV, Lo J, Gstaiger M, Krek W, Elson D, Arbeit J, Kipreos ET, Johnson RS.

Nat Genet. 1999 Oct;23(2):245-8.

PMID:
10508527
15.

The F-box protein SKP2 binds to the phosphorylated threonine 380 in cyclin E and regulates ubiquitin-dependent degradation of cyclin E.

Yeh KH, Kondo T, Zheng J, Tsvetkov LM, Blair J, Zhang H.

Biochem Biophys Res Commun. 2001 Mar 9;281(4):884-90.

PMID:
11237742
16.

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.

Bai C, Sen P, Hofmann K, Ma L, Goebl M, Harper JW, Elledge SJ.

Cell. 1996 Jul 26;86(2):263-74.

17.

The FBXW7 beta-form is suppressed in human glioma cells.

Gu Z, Inomata K, Ishizawa K, Horii A.

Biochem Biophys Res Commun. 2007 Mar 23;354(4):992-8. Epub 2007 Jan 24.

PMID:
17274947
18.

Drosophila Minus is required for cell proliferation and influences Cyclin E turnover.

Szuplewski S, Sandmann T, Hietakangas V, Cohen SM.

Genes Dev. 2009 Sep 1;23(17):1998-2003. doi: 10.1101/gad.1822409.

20.

SCF(Fbxw7/hCdc4) targets cyclin E2 for ubiquitin-dependent proteolysis.

Klotz K, Cepeda D, Tan Y, Sun D, Sangfelt O, Spruck C.

Exp Cell Res. 2009 Jul 1;315(11):1832-9. doi: 10.1016/j.yexcr.2008.11.017. Epub 2008 Dec 3.

PMID:
19084516
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