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Results: 1 to 20 of 139

1.

Crystal structure and substrate binding modeling of the uroporphyrinogen-III decarboxylase from Nicotiana tabacum. Implications for the catalytic mechanism.

Martins BM, Grimm B, Mock HP, Huber R, Messerschmidt A.

J Biol Chem. 2001 Nov 23;276(47):44108-16. Epub 2001 Aug 27.

PMID:
11524417
[PubMed - indexed for MEDLINE]
Free Article
2.

Crystal structure of human uroporphyrinogen decarboxylase.

Whitby FG, Phillips JD, Kushner JP, Hill CP.

EMBO J. 1998 May 1;17(9):2463-71.

PMID:
9564029
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Crystal structure of uroporphyrinogen decarboxylase from Bacillus subtilis.

Fan J, Liu Q, Hao Q, Teng M, Niu L.

J Bacteriol. 2007 May;189(9):3573-80. Epub 2006 Nov 22.

PMID:
17122346
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Tobacco uroporphyrinogen-III decarboxylase: characterization, crystallization and preliminary X-ray analysis.

Martins BM, Grimm B, Mock HP, Richter G, Huber R, Messerschmidt A.

Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1709-11. Epub 2001 Oct 25.

PMID:
11679753
[PubMed - indexed for MEDLINE]
5.

Localisation of Plasmodium falciparum uroporphyrinogen III decarboxylase of the heme-biosynthetic pathway in the apicoplast and characterisation of its catalytic properties.

Nagaraj VA, Arumugam R, Chandra NR, Prasad D, Rangarajan PN, Padmanaban G.

Int J Parasitol. 2009 Apr;39(5):559-68. doi: 10.1016/j.ijpara.2008.10.011. Epub 2008 Nov 14.

PMID:
19041871
[PubMed - indexed for MEDLINE]
6.

Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase.

Phillips JD, Whitby FG, Kushner JP, Hill CP.

EMBO J. 2003 Dec 1;22(23):6225-33.

PMID:
14633982
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The first branching point in porphyrin biosynthesis: a systematic docking, molecular dynamics and quantum mechanical/molecular mechanical study of substrate binding and mechanism of uroporphyrinogen-III decarboxylase.

Bushnell EA, Erdtman E, Llano J, Eriksson LA, Gauld JW.

J Comput Chem. 2011 Apr 15;32(5):822-34. doi: 10.1002/jcc.21661. Epub 2010 Oct 12.

PMID:
20941734
[PubMed - indexed for MEDLINE]
8.

A tale of two acids: when arginine is a more appropriate acid than H3O+.

Silva PJ, Schulz C, Jahn D, Jahn M, Ramos MJ.

J Phys Chem B. 2010 Jul 15;114(27):8994-9001. doi: 10.1021/jp100961s.

PMID:
20553007
[PubMed - indexed for MEDLINE]
9.

Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.

Phillips JD, Warby CA, Whitby FG, Kushner JP, Hill CP.

J Mol Biol. 2009 Jun 5;389(2):306-14. doi: 10.1016/j.jmb.2009.04.013. Epub 2009 Apr 10.

PMID:
19362562
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Density-functional study of mechanisms for the cofactor-free decarboxylation performed by uroporphyrinogen III decarboxylase.

Silva PJ, Ramos MJ.

J Phys Chem B. 2005 Sep 29;109(38):18195-200.

PMID:
16853337
[PubMed - indexed for MEDLINE]
11.

Uroporphyrinogen decarboxylase.

Elder GH, Roberts AG.

J Bioenerg Biomembr. 1995 Apr;27(2):207-14. Review.

PMID:
7592567
[PubMed - indexed for MEDLINE]
12.

Uroporphyrinogen decarboxylase in Saccharomyces cerevisiae. HEM12 gene sequence and evidence for two conserved glycines essential for enzymatic activity.

Garey JR, Labbe-Bois R, Chelstowska A, Rytka J, Harrison L, Kushner J, Labbe P.

Eur J Biochem. 1992 May 1;205(3):1011-6.

PMID:
1576986
[PubMed - indexed for MEDLINE]
Free Article
13.

Purification and properties of the uroporphyrinogen decarboxylase from Rhodobacter sphaeroides.

Jones RM, Jordan PM.

Biochem J. 1993 Aug 1;293 ( Pt 3):703-12.

PMID:
8352737
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds.

Forouhar F, Hussain M, Farid R, Benach J, Abashidze M, Edstrom WC, Vorobiev SM, Xiao R, Acton TB, Fu Z, Kim JJ, Miziorko HM, Montelione GT, Hunt JF.

J Biol Chem. 2006 Mar 17;281(11):7533-45. Epub 2005 Dec 5.

PMID:
16330546
[PubMed - indexed for MEDLINE]
Free Article
16.

Chitinolytic enzymes: catalysis, substrate binding, and their application.

Fukamizo T.

Curr Protein Pept Sci. 2000 Jul;1(1):105-24. Review.

PMID:
12369923
[PubMed - indexed for MEDLINE]
17.

Structure/function studies on a S-adenosyl-L-methionine-dependent uroporphyrinogen III C methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis.

Vévodová J, Graham RM, Raux E, Schubert HL, Roper DI, Brindley AA, Ian Scott A, Roessner CA, Stamford NP, Elizabeth Stroupe M, Getzoff ED, Warren MJ, Wilson KS.

J Mol Biol. 2004 Nov 19;344(2):419-33.

PMID:
15522295
[PubMed - indexed for MEDLINE]
18.

Human uroporphyrinogen III synthase: NMR-based mapping of the active site.

Cunha L, Kuti M, Bishop DF, Mezei M, Zeng L, Zhou MM, Desnick RJ.

Proteins. 2008 May 1;71(2):855-73.

PMID:
18004775
[PubMed - indexed for MEDLINE]
19.
20.

The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity.

Steegborn C, Messerschmidt A, Laber B, Streber W, Huber R, Clausen T.

J Mol Biol. 1999 Jul 30;290(5):983-96.

PMID:
10438597
[PubMed - indexed for MEDLINE]

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