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Items: 1 to 20 of 116


T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity.

Larochelle S, Chen J, Knights R, Pandur J, Morcillo P, Erdjument-Bromage H, Tempst P, Suter B, Fisher RP.

EMBO J. 2001 Jul 16;20(14):3749-59.


MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK.

Devault A, Martinez AM, Fesquet D, Labbé JC, Morin N, Tassan JP, Nigg EA, Cavadore JC, Dorée M.

EMBO J. 1995 Oct 16;14(20):5027-36.


Modulation of TFIIH-associated kinase activity by complex formation and its relationship with CTD phosphorylation of RNA polymerase II.

Watanabe Y, Fujimoto H, Watanabe T, Maekawa T, Masutani C, Hanaoka F, Ohkuma Y.

Genes Cells. 2000 May;5(5):407-23.


Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities.

Busso D, Keriel A, Sandrock B, Poterszman A, Gileadi O, Egly JM.

J Biol Chem. 2000 Jul 28;275(30):22815-23.


In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein.

Tassan JP, Jaquenoud M, Fry AM, Frutiger S, Hughes GJ, Nigg EA.

EMBO J. 1995 Nov 15;14(22):5608-17.


Is Cdk7/cyclin H/MAT1 the genuine cdk activating kinase in cycling Xenopus egg extracts?

Fesquet D, Morin N, Doree M, Devault A.

Oncogene. 1997 Sep;15(11):1303-7.


The cyclin H/cdk7/Mat1 kinase activity is regulated by CK2 phosphorylation of cyclin H.

Schneider E, Kartarius S, Schuster N, Montenarh M.

Oncogene. 2002 Aug 1;21(33):5031-7.


Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop.

Garrett S, Barton WA, Knights R, Jin P, Morgan DO, Fisher RP.

Mol Cell Biol. 2001 Jan;21(1):88-99.


Regulation of CAK kinase activity by p53.

Schneider E, Montenarh M, Wagner P.

Oncogene. 1998 Nov 26;17(21):2733-41.


Dual phosphorylation of the T-loop in cdk7: its role in controlling cyclin H binding and CAK activity.

Martinez AM, Afshar M, Martin F, Cavadore JC, Labbé JC, Dorée M.

EMBO J. 1997 Jan 15;16(2):343-54.


Regulation of CDK7-carboxyl-terminal domain kinase activity by the tumor suppressor p16(INK4A) contributes to cell cycle regulation.

Nishiwaki E, Turner SL, Harju S, Miyazaki S, Kashiwagi M, Koh J, Serizawa H.

Mol Cell Biol. 2000 Oct;20(20):7726-34.


Regulation of CDK7 substrate specificity by MAT1 and TFIIH.

Yankulov KY, Bentley DL.

EMBO J. 1997 Apr 1;16(7):1638-46.


p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.

Ko LJ, Shieh SY, Chen X, Jayaraman L, Tamai K, Taya Y, Prives C, Pan ZQ.

Mol Cell Biol. 1997 Dec;17(12):7220-9.


Cdk-activating kinase complex is a component of human transcription factor TFIIH.

Shiekhattar R, Mermelstein F, Fisher RP, Drapkin R, Dynlacht B, Wessling HC, Morgan DO, Reinberg D.

Nature. 1995 Mar 16;374(6519):283-7.


Xenopus phospho-CDK7/cyclin H expressed in baculoviral-infected insect cells.

Lawrie AM, Tito P, Hernandez H, Brown NR, Robinson CV, Endicott JA, Noble ME, Johnson LN.

Protein Expr Purif. 2001 Nov;23(2):252-60.


Molecular cloning of CDK7-associated human MAT1, a cyclin-dependent kinase-activating kinase (CAK) assembly factor.

Yee A, Nichols MA, Wu L, Hall FL, Kobayashi R, Xiong Y.

Cancer Res. 1995 Dec 15;55(24):6058-62.


The plant-specific kinase CDKF;1 is involved in activating phosphorylation of cyclin-dependent kinase-activating kinases in Arabidopsis.

Shimotohno A, Umeda-Hara C, Bisova K, Uchimiya H, Umeda M.

Plant Cell. 2004 Nov;16(11):2954-66. Epub 2004 Oct 14.


A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase.

Fisher RP, Morgan DO.

Cell. 1994 Aug 26;78(4):713-24.

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