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Items: 1 to 20 of 282

1.

Amyotrophic lateral sclerosis: pathogenesis.

Brown RH Jr, Robberecht W.

Semin Neurol. 2001 Jun;21(2):131-9. Review.

PMID:
11442322
2.

Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice.

Jaarsma D, Teuling E, Haasdijk ED, De Zeeuw CI, Hoogenraad CC.

J Neurosci. 2008 Feb 27;28(9):2075-88. doi: 10.1523/JNEUROSCI.5258-07.2008.

3.

Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease.

Nagai M, Aoki M, Miyoshi I, Kato M, Pasinelli P, Kasai N, Brown RH Jr, Itoyama Y.

J Neurosci. 2001 Dec 1;21(23):9246-54.

4.

Molecular biology of amyotrophic lateral sclerosis: insights from genetics.

Pasinelli P, Brown RH.

Nat Rev Neurosci. 2006 Sep;7(9):710-23. Review.

PMID:
16924260
5.

Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

Gowing G, Philips T, Van Wijmeersch B, Audet JN, Dewil M, Van Den Bosch L, Billiau AD, Robberecht W, Julien JP.

J Neurosci. 2008 Oct 8;28(41):10234-44. doi: 10.1523/JNEUROSCI.3494-08.2008.

6.

Genetics of amyotrophic lateral sclerosis.

Siddique T, Deng HX.

Hum Mol Genet. 1996;5 Spec No:1465-70. Review.

7.

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.

Wang J, Xu G, Slunt HH, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR.

Neurobiol Dis. 2005 Dec;20(3):943-52. Epub 2005 Jul 19.

PMID:
16046140
8.

Superoxide dismutase-1 mutation-related neurotoxicity in familial amyotrophic lateral sclerosis.

Shibata N, Hirano A, Yamamoto T, Kato Y, Kobayashi M.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2000 Jun;1(3):143-61. Review.

PMID:
11464949
9.

Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis.

Turner BJ, Atkin JD, Farg MA, Zang DW, Rembach A, Lopes EC, Patch JD, Hill AF, Cheema SS.

J Neurosci. 2005 Jan 5;25(1):108-17.

10.

Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.

Oh YK, Shin KS, Yuan J, Kang SJ.

J Neurochem. 2008 Feb;104(4):993-1005. doi: 10.1111/j.1471-4159.2007.05053.x.

12.

[Amyotrophic lateral sclerosis with the SOD1 mutations].

Aoki M, Warita H, Itoyama Y.

Rinsho Shinkeigaku. 2008 Nov;48(11):966-9. Review. Japanese.

PMID:
19198133
13.

Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS.

Gould TW, Buss RR, Vinsant S, Prevette D, Sun W, Knudson CM, Milligan CE, Oppenheim RW.

J Neurosci. 2006 Aug 23;26(34):8774-86.

14.
16.

Oxidative stress in ALS: key role in motor neuron injury and therapeutic target.

Barber SC, Shaw PJ.

Free Radic Biol Med. 2010 Mar 1;48(5):629-41. doi: 10.1016/j.freeradbiomed.2009.11.018. Epub 2009 Dec 4. Review.

PMID:
19969067
17.

Mitochondrial dysfunction and its role in motor neuron degeneration in ALS.

Manfredi G, Xu Z.

Mitochondrion. 2005 Apr;5(2):77-87. Review.

PMID:
16050975
18.

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.

Turner BJ, Talbot K.

Prog Neurobiol. 2008 May;85(1):94-134. doi: 10.1016/j.pneurobio.2008.01.001. Epub 2008 Jan 16. Review.

PMID:
18282652
19.

Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models.

Kato S, Kato M, Abe Y, Matsumura T, Nishino T, Aoki M, Itoyama Y, Asayama K, Awaya A, Hirano A, Ohama E.

Acta Neuropathol. 2005 Aug;110(2):101-12. Epub 2005 Jun 28.

PMID:
15983830
20.
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