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Items: 1 to 20 of 191


Role of PML and PML-RARalpha in Mad-mediated transcriptional repression.

Khan MM, Nomura T, Kim H, Kaul SC, Wadhwa R, Shinagawa T, Ichikawa-Iwata E, Zhong S, Pandolfi PP, Ishii S.

Mol Cell. 2001 Jun;7(6):1233-43.


Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.

Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M, Fanelli M, Ruthardt M, Ferrara FF, Zamir I, Seiser C, Grignani F, Lazar MA, Minucci S, Pelicci PG.

Nature. 1998 Feb 19;391(6669):815-8.


PML-RARalpha alleviates the transcriptional repression mediated by tumor suppressor Rb.

Khan MM, Nomura T, Kim H, Kaul SC, Wadhwa R, Zhong S, Pandolfi PP, Ishii S.

J Biol Chem. 2001 Nov 23;276(47):43491-4. Epub 2001 Oct 2.


Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo.

Atsumi A, Tomita A, Kiyoi H, Naoe T.

Biochem Biophys Res Commun. 2006 Jul 14;345(4):1471-80. Epub 2006 May 15.


In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.

Matsushita H, Scaglioni PP, Bhaumik M, Rego EM, Cai LF, Majid SM, Miyachi H, Kakizuka A, Miller WH Jr, Pandolfi PP.

J Exp Med. 2006 Apr 17;203(4):821-8. Epub 2006 Mar 20.


The fusion oncoprotein PML-RARalpha induces endoplasmic reticulum (ER)-associated degradation of N-CoR and ER stress.

Khan MM, Nomura T, Chiba T, Tanaka K, Yoshida H, Mori K, Ishii S.

J Biol Chem. 2004 Mar 19;279(12):11814-24. Epub 2003 Dec 29.


Role of the histone deacetylase complex in acute promyelocytic leukaemia.

Lin RJ, Nagy L, Inoue S, Shao W, Miller WH Jr, Evans RM.

Nature. 1998 Feb 19;391(6669):811-4.


The PML/RARalpha fusion protein inhibits tumor necrosis factor-alpha-induced apoptosis in U937 cells and acute promyelocytic leukemia blasts.

Testa U, Grignani F, Samoggia P, Zanetti C, Riccioni R, Lo Coco F, Diverio D, Felli N, Passerini CG, Grell M, Pelicci PG, Peschle C.

J Clin Invest. 1998 May 15;101(10):2278-89.


Coiled-coil domain of PML is essential for the aberrant dynamics of PML-RARalpha, resulting in sequestration and decreased mobility of SMRT.

Huang Y, Qiu J, Chen G, Dong S.

Biochem Biophys Res Commun. 2008 Jan 11;365(2):258-65. Epub 2007 Nov 6.


Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

He LZ, Guidez F, Tribioli C, Peruzzi D, Ruthardt M, Zelent A, Pandolfi PP.

Nat Genet. 1998 Feb;18(2):126-35.


The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression.

Dhordain P, Lin RJ, Quief S, Lantoine D, Kerckaert JP, Evans RM, Albagli O.

Nucleic Acids Res. 1998 Oct 15;26(20):4645-51.


Expression of SMRTbeta promotes ligand-induced activation of mutated and wild-type retinoid receptors.

Côté S, McNamara S, Brambilla D, Bianchini A, Rizzo G, del Rincón SV, Grignani F, Nervi C, Miller WH Jr.

Blood. 2004 Dec 15;104(13):4226-35. Epub 2004 Aug 19.

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