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Free and protein-bound glutamine have identical splanchnic extraction in healthy human volunteers.

Boza JJ, Dangin M, Moënnoz D, Montigon F, Vuichoud J, Jarret A, Pouteau E, Gremaud G, Oguey-Araymon S, Courtois D, Woupeyi A, Finot PA, Ballèvre O.

Am J Physiol Gastrointest Liver Physiol. 2001 Jul;281(1):G267-74.


A tracer bolus method for investigating glutamine kinetics in humans.

Mori M, Smedberg M, Klaude M, Tjäder I, Norberg A, Rooyackers O, Wernerman J.

PLoS One. 2014 May 8;9(5):e96601. doi: 10.1371/journal.pone.0096601. eCollection 2014.


Alterations in glutamine metabolism and its conversion to citrulline in sepsis.

Kao C, Hsu J, Bandi V, Jahoor F.

Am J Physiol Endocrinol Metab. 2013 Jun 15;304(12):E1359-64. doi: 10.1152/ajpendo.00628.2012. Epub 2013 Apr 23.


Splanchnic first pass disappearance of threonine and lysine do not differ in healthy men in the fed state.

Chapman KP, Elango R, Ball RO, Pencharz PB.

J Nutr. 2013 Mar;143(3):290-4. doi: 10.3945/jn.112.168328. Epub 2013 Jan 16.


Arginine synthesis from enteral glutamine in healthy adults in the fed state.

Tomlinson C, Rafii M, Ball RO, Pencharz P.

Am J Physiol Endocrinol Metab. 2011 Aug;301(2):E267-73. doi: 10.1152/ajpendo.00006.2011. Epub 2011 May 3.


Majority of dietary glutamine is utilized in first pass in preterm infants.

van der Schoor SR, Schierbeek H, Bet PM, Vermeulen MJ, Lafeber HN, van Goudoever JB, van Elburg RM.

Pediatr Res. 2010 Feb;67(2):194-9. doi: 10.1203/PDR.0b013e3181c34609.


Glutamine supplementation does not improve protein synthesis rate by the jejunal mucosa of the malnourished rat.

Tannus AF, Darmaun D, Ribas DF, Oliveira JE, Marchini JS.

Nutr Res. 2009 Aug;29(8):596-601. doi: 10.1016/j.nutres.2009.06.009.


Hydrolyzed dietary casein as compared with the intact protein reduces postprandial peripheral, but not whole-body, uptake of nitrogen in humans.

Deglaire A, Fromentin C, Fouillet H, Airinei G, Gaudichon C, Boutry C, Benamouzig R, Moughan PJ, Tomé D, Bos C.

Am J Clin Nutr. 2009 Oct;90(4):1011-22. doi: 10.3945/ajcn.2009.27548. Epub 2009 Aug 19.


Acid-induced amino side-chain interactions and secondary structure of solid poly-L-lysine probed by 15N and 13C solid state NMR and ab initio model calculations.

Dos A, Schimming V, Huot MC, Limbach HH.

J Am Chem Soc. 2009 Jun 10;131(22):7641-53. doi: 10.1021/ja901082a.


Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein.

Koopman R, Crombach N, Gijsen AP, Walrand S, Fauquant J, Kies AK, Lemosquet S, Saris WH, Boirie Y, van Loon LJ.

Am J Clin Nutr. 2009 Jul;90(1):106-15. doi: 10.3945/ajcn.2009.27474. Epub 2009 May 27.


Increasing plasma glutamine in postoperative patients fed an arginine-rich immune-enhancing diet--a pharmacokinetic randomized controlled study.

Loï C, Zazzo JF, Delpierre E, Niddam C, Neveux N, Curis E, Arnaud-Battandier F, Cynober L.

Crit Care Med. 2009 Feb;37(2):501-9. doi: 10.1097/CCM.0b013e3181958cba.


Combined enteral infusion of glutamine, carbohydrates, and antioxidants modulates gut protein metabolism in humans.

Coëffier M, Claeyssens S, Lecleire S, Leblond J, Coquard A, Bôle-Feysot C, Lavoinne A, Ducrotté P, Déchelotte P.

Am J Clin Nutr. 2008 Nov;88(5):1284-90.


Comparative aspects of tissue glutamine and proline metabolism.

Bertolo RF, Burrin DG.

J Nutr. 2008 Oct;138(10):2032S-2039S. Review.


Physical inactivity decreases whole body glutamine turnover independently from changes in proteolysis.

Agostini F, Heer M, Guarnieri G, Biolo G.

J Physiol. 2008 Oct 1;586(Pt 19):4775-81. doi: 10.1113/jphysiol.2008.153783. Epub 2008 Jul 31.


Glutamine is an important precursor for de novo synthesis of arginine in humans.

Ligthart-Melis GC, van de Poll MC, Boelens PG, Dejong CH, Deutz NE, van Leeuwen PA.

Am J Clin Nutr. 2008 May;87(5):1282-9.


Corticosteroids increase glutamine utilization in human splanchnic bed.

Thibault R, Welch S, Mauras N, Sager B, Altomare A, Haymond M, Darmaun D.

Am J Physiol Gastrointest Liver Physiol. 2008 Feb;294(2):G548-53. Epub 2007 Dec 27.


Splanchnic spillover of extracellular lipase-generated fatty acids in overweight and obese humans.

Nelson RH, Basu R, Johnson CM, Rizza RA, Miles JM.

Diabetes. 2007 Dec;56(12):2878-84. Epub 2007 Sep 19.


The route of administration (enteral or parenteral) affects the conversion of isotopically labeled L-[2-15N]glutamine into citrulline and arginine in humans.

Ligthart-Melis GC, van de Poll MC, Dejong CH, Boelens PG, Deutz NE, van Leeuwen PA.

JPEN J Parenter Enteral Nutr. 2007 Sep-Oct;31(5):343-48; discussion 349-50.


Dietary glutamate is almost entirely removed in its first pass through the splanchnic bed in premature infants.

Haÿs SP, Ordonez JM, Burrin DG, Sunehag AL.

Pediatr Res. 2007 Sep;62(3):353-6.

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