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Results: 1 to 20 of 171

1.

Promotion of S-phase entry and cell growth under serum starvation by SAG/ROC2/Rbx2/Hrt2, an E3 ubiquitin ligase component: association with inhibition of p27 accumulation.

Duan H, Tsvetkov LM, Liu Y, Song Y, Swaroop M, Wen R, Kung HF, Zhang H, Sun Y.

Mol Carcinog. 2001 Jan;30(1):37-46.

PMID:
11255262
[PubMed - indexed for MEDLINE]
3.

SAG/ROC/Rbx/Hrt, a zinc RING finger gene family: molecular cloning, biochemical properties, and biological functions.

Sun Y, Tan M, Duan H, Swaroop M.

Antioxid Redox Signal. 2001 Aug;3(4):635-50. Review.

PMID:
11554450
[PubMed - indexed for MEDLINE]
4.

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway.

Hara T, Kamura T, Nakayama K, Oshikawa K, Hatakeyama S, Nakayama K.

J Biol Chem. 2001 Dec 28;276(52):48937-43. Epub 2001 Oct 26.

PMID:
11682478
[PubMed - indexed for MEDLINE]
Free Article
5.

Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1.

Kim YS, Lee JY, Son MY, Park W, Bae YS.

J Biol Chem. 2003 Aug 1;278(31):28462-9. Epub 2003 May 13.

PMID:
12748192
[PubMed - indexed for MEDLINE]
Free Article
6.

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27.

Pagano M, Tam SW, Theodoras AM, Beer-Romero P, Del Sal G, Chau V, Yew PR, Draetta GF, Rolfe M.

Science. 1995 Aug 4;269(5224):682-5.

PMID:
7624798
[PubMed - indexed for MEDLINE]
7.

SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection.

Tan M, Gallegos JR, Gu Q, Huang Y, Li J, Jin Y, Lu H, Sun Y.

Neoplasia. 2006 Dec;8(12):1042-54.

PMID:
17217622
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Bcr-Abl kinase down-regulates cyclin-dependent kinase inhibitor p27 in human and murine cell lines.

Jonuleit T, van der Kuip H, Miething C, Michels H, Hallek M, Duyster J, Aulitzky WE.

Blood. 2000 Sep 1;96(5):1933-9.

PMID:
10961897
[PubMed - indexed for MEDLINE]
Free Article
9.

Yeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulation.

Swaroop M, Wang Y, Miller P, Duan H, Jatkoe T, Madore SJ, Sun Y.

Oncogene. 2000 Jun 1;19(24):2855-66.

PMID:
10851089
[PubMed - indexed for MEDLINE]
Free Article
10.

SAG/ROC2/RBX2 E3 ligase promotes UVB-induced skin hyperplasia, but not skin tumors, by simultaneously targeting c-Jun/AP-1 and p27.

He H, Gu Q, Zheng M, Normolle D, Sun Y.

Carcinogenesis. 2008 Apr;29(4):858-65. doi: 10.1093/carcin/bgn021. Epub 2008 Feb 6.

PMID:
18258608
[PubMed - indexed for MEDLINE]
Free Article
11.

SAG/ROC2/Rbx2/Hrt2, a component of SCF E3 ubiquitin ligase: genomic structure, a splicing variant, and two family pseudogenes.

Swaroop M, Gosink M, Sun Y.

DNA Cell Biol. 2001 Jul;20(7):425-34.

PMID:
11506706
[PubMed - indexed for MEDLINE]
12.

Growth arrest by troglitazone is mediated by p27Kip1 accumulation, which results from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells.

Motomura W, Takahashi N, Nagamine M, Sawamukai M, Tanno S, Kohgo Y, Okumura T.

Int J Cancer. 2004 Jan 1;108(1):41-6.

PMID:
14618613
[PubMed - indexed for MEDLINE]
13.

Involvement of two distinct ubiquitin E3 ligase systems for p27 degradation in corneal endothelial cells.

Lee JG, Kay EP.

Invest Ophthalmol Vis Sci. 2008 Jan;49(1):189-96. doi: 10.1167/iovs.07-0855.

PMID:
18172092
[PubMed - indexed for MEDLINE]
Free Article
14.

Inhibition of proteasome function induced apoptosis in gastric cancer.

Fan XM, Wong BC, Wang WP, Zhou XM, Cho CH, Yuen ST, Leung SY, Lin MC, Kung HF, Lam SK.

Int J Cancer. 2001 Aug 15;93(4):481-8.

PMID:
11477551
[PubMed - indexed for MEDLINE]
15.

Clinical and biological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma: modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis.

Masuda TA, Inoue H, Sonoda H, Mine S, Yoshikawa Y, Nakayama K, Nakayama K, Mori M.

Cancer Res. 2002 Jul 1;62(13):3819-25.

PMID:
12097295
[PubMed - indexed for MEDLINE]
Free Article
16.

PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).

Mamillapalli R, Gavrilova N, Mihaylova VT, Tsvetkov LM, Wu H, Zhang H, Sun H.

Curr Biol. 2001 Feb 20;11(4):263-7.

PMID:
11250155
[PubMed - indexed for MEDLINE]
Free Article
17.

Changes in p21(Cip1) and p27(Kip1) expression are not required for cell cycle entry and progression to S phase in Swiss 3T3 cells.

Promwikorn W, Hawley SR, Pennington SR.

Cell Signal. 2000 Oct;12(9-10):619-27.

PMID:
11080613
[PubMed - indexed for MEDLINE]
18.

The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.

Lu L, Schulz H, Wolf DA.

BMC Cell Biol. 2002 Aug 20;3:22. Epub 2002 Aug 20.

PMID:
12188931
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through accumulation of p21(WAF1) and p27(Kip1) proteins.

Ezoe S, Matsumura I, Nakata S, Gale K, Ishihara K, Minegishi N, Machii T, Kitamura T, Yamamoto M, Enver T, Kanakura Y.

Blood. 2002 Nov 15;100(10):3512-20. Epub 2002 Jul 12.

PMID:
12393444
[PubMed - indexed for MEDLINE]
Free Article

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