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Items: 1 to 20 of 56

1.

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells.

Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, Hung MC.

Nat Cell Biol. 2001 Mar;3(3):245-52.

PMID:
11231573
2.
3.

GRB-7 facilitates HER-2/Neu-mediated signal transduction and tumor formation.

Bai T, Luoh SW.

Carcinogenesis. 2008 Mar;29(3):473-9. Epub 2007 Oct 4.

6.

HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway.

Wen Y, Hu MC, Makino K, Spohn B, Bartholomeusz G, Yan DH, Hung MC.

Cancer Res. 2000 Dec 15;60(24):6841-5.

7.

Down-regulation of neu/HER-2 by interferon-gamma in prostate cancer cells.

Kominsky SL, Hobeika AC, Lake FA, Torres BA, Johnson HM.

Cancer Res. 2000 Jul 15;60(14):3904-8.

8.

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation.

Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC.

Nat Cell Biol. 2001 Nov;3(11):973-82. Erratum in: Nat Cell Biol 2002 Sep;4(9):736.

PMID:
11715018
9.

Novel targets of Akt, p21(Cipl/WAF1), and MDM2.

Zhou BP, Hung MC.

Semin Oncol. 2002 Jun;29(3 Suppl 11):62-70. Review.

PMID:
12138399
12.

Increased cell size and Akt activation in HER-2/neu-overexpressing invasive ductal carcinoma of the breast.

Sastre-Garau X, Genin P, Rousseau A, Al Ghuzlan A, Nicolas A, Fréneaux P, Rosty C, Sigal-Zafrani B, Couturier J, Thiery JP, Magdelénat H, Vincent-Salomon A.

Histopathology. 2004 Aug;45(2):142-7.

PMID:
15279632
13.

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway.

Zhou BP, Hu MC, Miller SA, Yu Z, Xia W, Lin SY, Hung MC.

J Biol Chem. 2000 Mar 17;275(11):8027-31.

14.

Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells.

Romieu-Mourez R, Landesman-Bollag E, Seldin DC, Sonenshein GE.

Cancer Res. 2002 Nov 15;62(22):6770-8.

15.
17.

The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation.

Holbro T, Beerli RR, Maurer F, Koziczak M, Barbas CF 3rd, Hynes NE.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8933-8. Epub 2003 Jul 9.

18.

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase.

Yu D, Jing T, Liu B, Yao J, Tan M, McDonnell TJ, Hung MC.

Mol Cell. 1998 Nov;2(5):581-91.

19.
20.

Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation.

Kondapaka SB, Singh SS, Dasmahapatra GP, Sausville EA, Roy KK.

Mol Cancer Ther. 2003 Nov;2(11):1093-103.

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