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Results: 1 to 20 of 173

1.

Ukrain(TM), a semisynthetic Chelidonium majus alkaloid derivative, acts by inhibition of tubulin polymerization in normal and malignant cell lines.

Panzer A, Hamel E, Joubert AM, Bianchi PC, Seegers JC.

Cancer Lett. 2000 Nov 28;160(2):149-57.

PMID:
11053644
[PubMed - indexed for MEDLINE]
2.

The antimitotic effects of Ukrain, a Chelidonium majus alkaloid derivative, are reversible in vitro.

Panzer A, Joubert AM, Bianchi PC, Seegers JC.

Cancer Lett. 2000 Mar 13;150(1):85-92.

PMID:
10755391
[PubMed - indexed for MEDLINE]
3.

Ukrain, an alkaloid thiophosphoric acid derivative of Chelidonium majus L. protects human fibroblasts but not human tumour cells in vitro against ionizing radiation.

Cordes N, Plasswilm L, Bamberg M, Rodemann HP.

Int J Radiat Biol. 2002 Jan;78(1):17-27.

PMID:
11747550
[PubMed - indexed for MEDLINE]
4.

Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway.

Habermehl D, Kammerer B, Handrick R, Eldh T, Gruber C, Cordes N, Daniel PT, Plasswilm L, Bamberg M, Belka C, Jendrossek V.

BMC Cancer. 2006 Jan 17;6:14.

PMID:
16417634
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The effects of chelidonine on tubulin polymerisation, cell cycle progression and selected signal transmission pathways.

Panzer A, Joubert AM, Bianchi PC, Hamel E, Seegers JC.

Eur J Cell Biol. 2001 Jan;80(1):111-8.

PMID:
11211931
[PubMed - indexed for MEDLINE]
6.

Ukrain: a novel antitumor drug.

Uglyanitsa KN, Nefyodov LI, Doroshenko YM, Nowicky JW, Volchek IV, Brzosko WJ, Hodysh YJ.

Drugs Exp Clin Res. 2000;26(5-6):341-56. Review.

PMID:
11345050
[PubMed - indexed for MEDLINE]
7.

Chemical analyses of Ukrain, a semi-synthetic Chelidonium majus alkaloid derivative, fail to confirm its trimeric structure.

Panzer A, Joubert AM, Eloff JN, Albrecht CF, Erasmus E, Seegers JC.

Cancer Lett. 2000 Nov 28;160(2):237-41.

PMID:
11053654
[PubMed - indexed for MEDLINE]
8.

Bcl-2 overexpression protects human keratinocyte cells from Ukrain-induced apoptosis but not from G2/M arrest.

Roublevskaia IN, Haake AR, Polevoda BV.

Drugs Exp Clin Res. 2000;26(5-6):149-56.

PMID:
11345021
[PubMed - indexed for MEDLINE]
9.

Selective inhibition of in vitro cell growth by the anti-tumour drug Ukrain.

Hohenwarter O, Strutzenberger K, Katinger H, Liepins A, Nowicky JW.

Drugs Exp Clin Res. 1992;18 Suppl:1-4.

PMID:
1305034
[PubMed - indexed for MEDLINE]
10.

Modulation of immune effector cell cytolytic activity and tumour growth inhibition in vivo by Ukrain (NSC 631570).

Liepins A, Nowicky JW.

Drugs Exp Clin Res. 1996;22(3-5):103-13.

PMID:
8899312
[PubMed - indexed for MEDLINE]
11.

Enhancement of macrophage tumouricidal activity by the alkaloid derivative Ukrain. In vitro and in vivo studies.

Sotomayor EM, Rao K, Lopez DM, Liepins A.

Drugs Exp Clin Res. 1992;18 Suppl:5-11.

PMID:
1305044
[PubMed - indexed for MEDLINE]
12.

Induced apoptosis in human prostate cancer cell line LNCaP by Ukrain.

Roublevskaia IN, Haake AR, Ludlow JW, Polevoda BV.

Drugs Exp Clin Res. 2000;26(5-6):141-7.

PMID:
11345020
[PubMed - indexed for MEDLINE]
13.

In-vitro toxicity of Ukrain against human Ewing tumor cell lines.

Lanvers-Kaminsky C, Nolting DM, Köster J, Schröder A, Sandkötter J, Boos J.

Anticancer Drugs. 2006 Oct;17(9):1025-30.

PMID:
17001175
[PubMed - indexed for MEDLINE]
14.

Activation of spleen cell lytic activity by the alkaloid thiophosphoric acid derivative: Ukrain.

Liepins A, Nowicky JW.

Int J Immunopharmacol. 1992 Nov;14(8):1437-42.

PMID:
1464476
[PubMed - indexed for MEDLINE]
15.

Comparative study of the cytostatic effects of Oliphen and Ukrain.

Voltchek I, Kamyshentsev M, Lavinsky Y, Nowicky J, Medvedev Y, Litvinchuk L.

J Chemother. 1996 Apr;8(2):144-6.

PMID:
8708746
[PubMed - indexed for MEDLINE]
16.

Ukrain (NSC-631570) in experimental and clinical studies: a review.

Jagiello-Wójtowicz E, Kleinrok Z, Urbanska EM.

Drugs Exp Clin Res. 1998;24(5-6):213-9. Review.

PMID:
10190077
[PubMed - indexed for MEDLINE]
17.

NF-kappaB does not influence the induction of apoptosis by Ukrain.

Mendoza J, Zamora R, Gallardo JC, Ceballos G, Aldana A, Espinosa M, Maldonado V, Melendez-Zajgla J.

Cancer Biol Ther. 2006 Jul;5(7):788-93. Epub 2006 Jul 26.

PMID:
16721042
[PubMed - indexed for MEDLINE]
Free Article
18.

Ukrain (NSC-631570) influences on bone status: a review.

Jabłoński M.

Drugs Exp Clin Res. 2000;26(5-6):317-20. Review.

PMID:
11345045
[PubMed - indexed for MEDLINE]
19.

In vitro effects of Chelidonium majus L. alkaloid thiophosphoric acid conjugates (Ukrain) on the phenotype of normal human lymphocytes.

Slesak B, Nowicky JW, Harłozinska A.

Drugs Exp Clin Res. 1992;18 Suppl:17-21.

PMID:
1305038
[PubMed - indexed for MEDLINE]
20.

Fibronectin and laminin increase resistance to ionizing radiation and the cytotoxic drug Ukrain in human tumour and normal cells in vitro.

Cordes N, Blaese MA, Plasswilm L, Rodemann HP, Van Beuningen D.

Int J Radiat Biol. 2003 Sep;79(9):709-20.

PMID:
14703944
[PubMed - indexed for MEDLINE]
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