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Results: 1 to 20 of 172

1.

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors.

Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, Auwerx J, Mangelsdorf DJ.

Mol Cell. 2000 Sep;6(3):507-15.

PMID:
11030331
[PubMed - indexed for MEDLINE]
Free Article
2.

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.

Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, Moore LB, Galardi C, Wilson JG, Lewis MC, Roth ME, Maloney PR, Willson TM, Kliewer SA.

Mol Cell. 2000 Sep;6(3):517-26.

PMID:
11030332
[PubMed - indexed for MEDLINE]
Free Article
3.

Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP.

Davis RA, Miyake JH, Hui TY, Spann NJ.

J Lipid Res. 2002 Apr;43(4):533-43. Review.

PMID:
11907135
[PubMed - indexed for MEDLINE]
Free Article
4.

FXR-mediated down-regulation of CYP7A1 dominates LXRalpha in long-term cholesterol-fed NZW rabbits.

Xu G, Li H, Pan LX, Shang Q, Honda A, Ananthanarayanan M, Erickson SK, Shneider BL, Shefer S, Bollineni J, Forman BM, Matsuzaki Y, Suchy FJ, Tint GS, Salen G.

J Lipid Res. 2003 Oct;44(10):1956-62. Epub 2003 Aug 1.

PMID:
12897188
[PubMed - indexed for MEDLINE]
Free Article
6.

Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids.

Bramlett KS, Yao S, Burris TP.

Mol Genet Metab. 2000 Dec;71(4):609-15.

PMID:
11136553
[PubMed - indexed for MEDLINE]
7.

Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.

Chen W, Owsley E, Yang Y, Stroup D, Chiang JY.

J Lipid Res. 2001 Sep;42(9):1402-12.

PMID:
11518759
[PubMed - indexed for MEDLINE]
Free Article
8.

Liver receptor homolog 1 transcriptionally regulates human bile salt export pump expression.

Song X, Kaimal R, Yan B, Deng R.

J Lipid Res. 2008 May;49(5):973-84. doi: 10.1194/jlr.M700417-JLR200. Epub 2008 Feb 12.

PMID:
18270374
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle.

De Fabiani E, Mitro N, Gilardi F, Caruso D, Galli G, Crestani M.

J Biol Chem. 2003 Oct 3;278(40):39124-32. Epub 2003 Jul 15.

PMID:
12865425
[PubMed - indexed for MEDLINE]
Free Article
10.

LXR alpha is the dominant regulator of CYP7A1 transcription.

Gupta S, Pandak WM, Hylemon PB.

Biochem Biophys Res Commun. 2002 Apr 26;293(1):338-43.

PMID:
12054605
[PubMed - indexed for MEDLINE]
11.

Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.

Mitro N, Godio C, De Fabiani E, Scotti E, Galmozzi A, Gilardi F, Caruso D, Vigil Chacon AB, Crestani M.

Hepatology. 2007 Sep;46(3):885-97.

PMID:
17654698
[PubMed - indexed for MEDLINE]
12.

Role of an mSin3A-Swi/Snf chromatin remodeling complex in the feedback repression of bile acid biosynthesis by SHP.

Kemper JK, Kim H, Miao J, Bhalla S, Bae Y.

Mol Cell Biol. 2004 Sep;24(17):7707-19.

PMID:
15314177
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway.

Gupta S, Stravitz RT, Dent P, Hylemon PB.

J Biol Chem. 2001 May 11;276(19):15816-22. Epub 2001 Feb 13.

PMID:
11278771
[PubMed - indexed for MEDLINE]
Free Article
14.

Identification of a nuclear receptor for bile acids.

Makishima M, Okamoto AY, Repa JJ, Tu H, Learned RM, Luk A, Hull MV, Lustig KD, Mangelsdorf DJ, Shan B.

Science. 1999 May 21;284(5418):1362-5.

PMID:
10334992
[PubMed - indexed for MEDLINE]
Free Article
15.

Suppression of cholesterol 7alpha-hydroxylase transcription and bile acid synthesis by an alpha1-antitrypsin peptide via interaction with alpha1-fetoprotein transcription factor.

Gerbod-Giannone MC, Del Castillo-Olivares A, Janciauskiene S, Gil G, Hylemon PB.

J Biol Chem. 2002 Nov 8;277(45):42973-80. Epub 2002 Sep 9.

PMID:
12223476
[PubMed - indexed for MEDLINE]
Free Article
16.

Redundant pathways for negative feedback regulation of bile acid production.

Wang L, Lee YK, Bundman D, Han Y, Thevananther S, Kim CS, Chua SS, Wei P, Heyman RA, Karin M, Moore DD.

Dev Cell. 2002 Jun;2(6):721-31.

PMID:
12062085
[PubMed - indexed for MEDLINE]
Free Article
17.

Bile acids reduce SR-BI expression in hepatocytes by a pathway involving FXR/RXR, SHP, and LRH-1.

Malerød L, Sporstøl M, Juvet LK, Mousavi SA, Gjøen T, Berg T, Roos N, Eskild W.

Biochem Biophys Res Commun. 2005 Nov 4;336(4):1096-105.

PMID:
16168958
[PubMed - indexed for MEDLINE]
18.

Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis.

Sanyal S, Båvner A, Haroniti A, Nilsson LM, Lundåsen T, Rehnmark S, Witt MR, Einarsson C, Talianidis I, Gustafsson JA, Treuter E.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15665-70. Epub 2007 Sep 25.

PMID:
17895379
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Species-specific mechanisms for cholesterol 7alpha-hydroxylase (CYP7A1) regulation by drugs and bile acids.

Handschin C, Gnerre C, Fraser DJ, Martinez-Jimenez C, Jover R, Meyer UA.

Arch Biochem Biophys. 2005 Feb 1;434(1):75-85.

PMID:
15629111
[PubMed - indexed for MEDLINE]
20.

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