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Results: 1 to 20 of 581

1.

CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase.

Tan J, Town T, Mori T, Wu Y, Saxe M, Crawford F, Mullan M.

J Neurosci. 2000 Oct 15;20(20):7587-94.

PMID:
11027218
[PubMed - indexed for MEDLINE]
Free Article
2.

CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway.

Tan J, Town T, Mullan M.

J Biol Chem. 2000 Nov 24;275(47):37224-31.

PMID:
10978311
[PubMed - indexed for MEDLINE]
Free Article
3.

CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.

Zhu Y, Hou H, Nikolic WV, Ehrhart J, Rrapo E, Bickford P, Giunta B, Tan J.

PLoS One. 2008 May 14;3(5):e2135. doi: 10.1371/journal.pone.0002135.

PMID:
18478117
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs).

Dukic-Stefanovic S, Gasic-Milenkovic J, Deuther-Conrad W, Münch G.

J Neurochem. 2003 Oct;87(1):44-55.

PMID:
12969251
[PubMed - indexed for MEDLINE]
5.

MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.

Culbert AA, Skaper SD, Howlett DR, Evans NA, Facci L, Soden PE, Seymour ZM, Guillot F, Gaestel M, Richardson JC.

J Biol Chem. 2006 Aug 18;281(33):23658-67. Epub 2006 Jun 14.

PMID:
16774924
[PubMed - indexed for MEDLINE]
Free Article
6.

Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10.

Tan J, Town T, Saxe M, Paris D, Wu Y, Mullan M.

J Immunol. 1999 Dec 15;163(12):6614-21.

PMID:
10586056
[PubMed - indexed for MEDLINE]
Free Article
7.

Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.

Tan J, Town T, Paris D, Mori T, Suo Z, Crawford F, Mattson MP, Flavell RA, Mullan M.

Science. 1999 Dec 17;286(5448):2352-5.

PMID:
10600748
[PubMed - indexed for MEDLINE]
Free Article
8.

CD45 isoform RB as a molecular target to oppose lipopolysaccharide-induced microglial activation in mice.

Townsend KP, Vendrame M, Ehrhart J, Faza B, Zeng J, Town T, Tan J.

Neurosci Lett. 2004 May 13;362(1):26-30.

PMID:
15147773
[PubMed - indexed for MEDLINE]
9.

Microglial signaling by amyloid beta protein through mitogen-activated protein kinase mediating phosphorylation of MARCKS.

Hasegawa H, Nakai M, Tanimukai S, Taniguchi T, Terashima A, Kawamata T, Fukunaga K, Miyamoto E, Misaki K, Mukai H, Tanaka C.

Neuroreport. 2001 Aug 8;12(11):2567-71.

PMID:
11496150
[PubMed - indexed for MEDLINE]
10.

Hypoxia induces nitric oxide production in mouse microglia via p38 mitogen-activated protein kinase pathway.

Park SY, Lee H, Hur J, Kim SY, Kim H, Park JH, Cha S, Kang SS, Cho GJ, Choi WS, Suk K.

Brain Res Mol Brain Res. 2002 Oct 30;107(1):9-16.

PMID:
12414118
[PubMed - indexed for MEDLINE]
11.

Abnormality of G-protein-coupled receptor kinases at prodromal and early stages of Alzheimer's disease: an association with early beta-amyloid accumulation.

Suo Z, Wu M, Citron BA, Wong GT, Festoff BW.

J Neurosci. 2004 Mar 31;24(13):3444-52.

PMID:
15056724
[PubMed - indexed for MEDLINE]
Free Article
12.

IL-4 down-regulates lipopolysaccharide-induced formyl peptide receptor 2 in murine microglial cells by inhibiting the activation of mitogen-activated protein kinases.

Iribarren P, Cui YH, Le Y, Ying G, Zhang X, Gong W, Wang JM.

J Immunol. 2003 Nov 15;171(10):5482-8.

PMID:
14607954
[PubMed - indexed for MEDLINE]
Free Article
13.

HIV-1 Tat-induced microglial activation and neuronal damage is inhibited via CD45 modulation: A potential new treatment target for HAND.

Jin J, Lam L, Sadic E, Fernandez F, Tan J, Giunta B.

Am J Transl Res. 2012;4(3):302-15. Epub 2012 Jul 22.

PMID:
22937208
[PubMed]
Free PMC Article
14.

Beta-amyloid peptide potentiates inflammatory responses induced by lipopolysaccharide, interferon -gamma and 'advanced glycation endproducts' in a murine microglia cell line.

Gasic-Milenkovic J, Dukic-Stefanovic S, Deuther-Conrad W, Gärtner U, Münch G.

Eur J Neurosci. 2003 Feb;17(4):813-21.

PMID:
12603271
[PubMed - indexed for MEDLINE]
15.

Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells.

D'Alimonte I, Flati V, D'Auro M, Toniato E, Martinotti S, Rathbone MP, Jiang S, Ballerini P, Di Iorio P, Caciagli F, Ciccarelli R.

J Immunol. 2007 Jan 15;178(2):720-31. Erratum in: J Immunol. 2007 Apr 15;178(8):5399.

PMID:
17202332
[PubMed - indexed for MEDLINE]
Free Article
16.

beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

Combs CK, Karlo JC, Kao SC, Landreth GE.

J Neurosci. 2001 Feb 15;21(4):1179-88.

PMID:
11160388
[PubMed - indexed for MEDLINE]
Free Article
17.

Blueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinase.

Zhu Y, Bickford PC, Sanberg P, Giunta B, Tan J.

Rejuvenation Res. 2008 Oct;11(5):891-901. doi: 10.1089/rej.2008.0757.

PMID:
18789000
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation.

Koistinaho M, Kettunen MI, Goldsteins G, Keinänen R, Salminen A, Ort M, Bures J, Liu D, Kauppinen RA, Higgins LS, Koistinaho J.

Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1610-5. Epub 2002 Jan 29.

PMID:
11818564
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.

Jantzen PT, Connor KE, DiCarlo G, Wenk GL, Wallace JL, Rojiani AM, Coppola D, Morgan D, Gordon MN.

J Neurosci. 2002 Mar 15;22(6):2246-54.

PMID:
11896164
[PubMed - indexed for MEDLINE]
Free Article
20.

Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia.

Franciosi S, Ryu JK, Choi HB, Radov L, Kim SU, McLarnon JG.

J Neurosci. 2006 Nov 8;26(45):11652-64.

PMID:
17093087
[PubMed - indexed for MEDLINE]
Free Article

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