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Results: 1 to 20 of 91

1.

Negative regulation of the serine/threonine kinase B-Raf by Akt.

Guan KL, Figueroa C, Brtva TR, Zhu T, Taylor J, Barber TD, Vojtek AB.

J Biol Chem. 2000 Sep 1;275(35):27354-9.

PMID:
10869359
[PubMed - indexed for MEDLINE]
Free Article
2.

Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.

Zhang BH, Tang ED, Zhu T, Greenberg ME, Vojtek AB, Guan KL.

J Biol Chem. 2001 Aug 24;276(34):31620-6. Epub 2001 Jun 15.

PMID:
11410590
[PubMed - indexed for MEDLINE]
Free Article
3.

Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel.

Mabuchi S, Ohmichi M, Kimura A, Hisamoto K, Hayakawa J, Nishio Y, Adachi K, Takahashi K, Arimoto-Ishida E, Nakatsuji Y, Tasaka K, Murata Y.

J Biol Chem. 2002 Sep 6;277(36):33490-500. Epub 2002 Jun 26.

PMID:
12087097
[PubMed - indexed for MEDLINE]
Free Article
4.

Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells.

Reusch HP, Zimmermann S, Schaefer M, Paul M, Moelling K.

J Biol Chem. 2001 Sep 7;276(36):33630-7. Epub 2001 Jul 6.

PMID:
11443134
[PubMed - indexed for MEDLINE]
Free Article
5.
6.

Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.

Zheng CF, Guan KL.

EMBO J. 1994 Mar 1;13(5):1123-31.

PMID:
8131746
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Phosphorylation and regulation of Raf by Akt (protein kinase B).

Zimmermann S, Moelling K.

Science. 1999 Nov 26;286(5445):1741-4.

PMID:
10576742
[PubMed - indexed for MEDLINE]
Free Article
8.

Negative regulation of Raf-1 by phosphorylation of serine 621.

Mischak H, Seitz T, Janosch P, Eulitz M, Steen H, Schellerer M, Philipp A, Kolch W.

Mol Cell Biol. 1996 Oct;16(10):5409-18.

PMID:
8816453
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Phosphorylation of 338SSYY341 regulates specific interaction between Raf-1 and MEK1.

Xiang X, Zang M, Waelde CA, Wen R, Luo Z.

J Biol Chem. 2002 Nov 22;277(47):44996-5003. Epub 2002 Sep 19.

PMID:
12244094
[PubMed - indexed for MEDLINE]
Free Article
10.

Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling.

Diaz B, Barnard D, Filson A, MacDonald S, King A, Marshall M.

Mol Cell Biol. 1997 Aug;17(8):4509-16.

PMID:
9234708
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition.

Tran NH, Frost JA.

J Biol Chem. 2003 Mar 28;278(13):11221-6. Epub 2003 Jan 27.

PMID:
12551923
[PubMed - indexed for MEDLINE]
Free Article
12.

95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site.

Stephens RM, Sithanandam G, Copeland TD, Kaplan DR, Rapp UR, Morrison DK.

Mol Cell Biol. 1992 Sep;12(9):3733-42.

PMID:
1508179
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338.

King AJ, Sun H, Diaz B, Barnard D, Miao W, Bagrodia S, Marshall MS.

Nature. 1998 Nov 12;396(6707):180-3. Erratum in: Nature 2000 Jul 27;406(6794):439.

PMID:
9823899
[PubMed - indexed for MEDLINE]
14.

Phosphorylation of HDM2 by Akt.

Ashcroft M, Ludwig RL, Woods DB, Copeland TD, Weber HO, MacRae EJ, Vousden KH.

Oncogene. 2002 Mar 27;21(13):1955-62.

PMID:
11960368
[PubMed - indexed for MEDLINE]
Free Article
15.

Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1.

Bosch E, Cherwinski H, Peterson D, McMahon M.

Oncogene. 1997 Aug 28;15(9):1021-33.

PMID:
9285556
[PubMed - indexed for MEDLINE]
Free Article
16.

c-Met-Akt pathway-mediated enhancement of inhibitory c-Raf phosphorylation is involved in vitamin K1 and sorafenib synergy on HCC growth inhibition.

Carr BI, Wang Z, Wang M, Cavallini A, D'Alessandro R, Refolo MG.

Cancer Biol Ther. 2011 Sep 15;12(6):531-8. doi: 10.4161/cbt.12.6.16053. Epub 2011 Sep 15.

PMID:
21734462
[PubMed - indexed for MEDLINE]
Free Article
17.

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site.

Toker A, Newton AC.

J Biol Chem. 2000 Mar 24;275(12):8271-4.

PMID:
10722653
[PubMed - indexed for MEDLINE]
Free Article
18.

Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK binding.

Zhu J, Balan V, Bronisz A, Balan K, Sun H, Leicht DT, Luo Z, Qin J, Avruch J, Tzivion G.

Mol Biol Cell. 2005 Oct;16(10):4733-44. Epub 2005 Aug 10.

PMID:
16093354
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Regulation of the Raf kinase by phosphorylation.

Zhang BH, Guan KL.

Exp Lung Res. 2001 Apr-May;27(3):269-95.

PMID:
11293329
[PubMed - indexed for MEDLINE]
20.

Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells.

Wu X, Noh SJ, Zhou G, Dixon JE, Guan KL.

J Biol Chem. 1996 Feb 9;271(6):3265-71.

PMID:
8621729
[PubMed - indexed for MEDLINE]
Free Article

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