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Results: 1 to 20 of 405

1.

Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.

Jensen J, Heller RS, Funder-Nielsen T, Pedersen EE, Lindsell C, Weinmaster G, Madsen OD, Serup P.

Diabetes. 2000 Feb;49(2):163-76.

PMID:
10868931
[PubMed - indexed for MEDLINE]
2.

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas.

Gradwohl G, Dierich A, LeMeur M, Guillemot F.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1607-11.

PMID:
10677506
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.

Schwitzgebel VM, Scheel DW, Conners JR, Kalamaras J, Lee JE, Anderson DJ, Sussel L, Johnson JD, German MS.

Development. 2000 Aug;127(16):3533-42.

PMID:
10903178
[PubMed - indexed for MEDLINE]
Free Article
4.

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.

Soyer J, Flasse L, Raffelsberger W, Beucher A, Orvain C, Peers B, Ravassard P, Vermot J, Voz ML, Mellitzer G, Gradwohl G.

Development. 2010 Jan;137(2):203-12. doi: 10.1242/dev.041673.

PMID:
20040487
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development.

Hald J, Hjorth JP, German MS, Madsen OD, Serup P, Jensen J.

Dev Biol. 2003 Aug 15;260(2):426-37.

PMID:
12921743
[PubMed - indexed for MEDLINE]
6.

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.

Johansson KA, Dursun U, Jordan N, Gu G, Beermann F, Gradwohl G, Grapin-Botton A.

Dev Cell. 2007 Mar;12(3):457-65.

PMID:
17336910
[PubMed - indexed for MEDLINE]
Free Article
7.
8.

The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells.

Nelson SB, Schaffer AE, Sander M.

Development. 2007 Jul;134(13):2491-500. Epub 2007 May 30.

PMID:
17537793
[PubMed - indexed for MEDLINE]
Free Article
9.

GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development.

Harmon EB, Apelqvist AA, Smart NG, Gu X, Osborne DH, Kim SK.

Development. 2004 Dec;131(24):6163-74. Epub 2004 Nov 17.

PMID:
15548585
[PubMed - indexed for MEDLINE]
Free Article
10.

Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas.

Ahnfelt-Rønne J, Hald J, Bødker A, Yassin H, Serup P, Hecksher-Sørensen J.

BMC Dev Biol. 2007 Jun 7;7:63.

PMID:
17555568
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Regulation of the pancreatic pro-endocrine gene neurogenin3.

Lee JC, Smith SB, Watada H, Lin J, Scheel D, Wang J, Mirmira RG, German MS.

Diabetes. 2001 May;50(5):928-36. Erratum in: Diabetes 2001 Jun;50(6):1512.

PMID:
11334435
[PubMed - indexed for MEDLINE]
Free Article
12.

FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development.

Norgaard GA, Jensen JN, Jensen J.

Dev Biol. 2003 Dec 15;264(2):323-38.

PMID:
14651921
[PubMed - indexed for MEDLINE]
13.

The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.

Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA.

J Clin Invest. 2009 Jul;119(7):1888-98. doi: 10.1172/JCI37028.

PMID:
19487809
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis.

Gu G, Brown JR, Melton DA.

Mech Dev. 2003 Jan;120(1):35-43. Review.

PMID:
12490294
[PubMed - indexed for MEDLINE]
15.

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3.

Heremans Y, Van De Casteele M, in't Veld P, Gradwohl G, Serup P, Madsen O, Pipeleers D, Heimberg H.

J Cell Biol. 2002 Oct 28;159(2):303-12. Epub 2002 Oct 28.

PMID:
12403815
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window.

Cras-Méneur C, Li L, Kopan R, Permutt MA.

Genes Dev. 2009 Sep 1;23(17):2088-101. doi: 10.1101/gad.1800209.

PMID:
19723764
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Characterization of c-Kit and nestin expression during islet cell development in the prenatal and postnatal rat pancreas.

Yashpal NK, Li J, Wang R.

Dev Dyn. 2004 Apr;229(4):813-25.

PMID:
15042705
[PubMed - indexed for MEDLINE]
Free Article
18.

SOX9 regulates endocrine cell differentiation during human fetal pancreas development.

McDonald E, Li J, Krishnamurthy M, Fellows GF, Goodyer CG, Wang R.

Int J Biochem Cell Biol. 2012 Jan;44(1):72-83. doi: 10.1016/j.biocel.2011.09.008. Epub 2011 Sep 29.

PMID:
21983268
[PubMed - indexed for MEDLINE]
19.

MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3.

Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA.

Dev Biol. 2007 Nov 15;311(2):603-12. Epub 2007 Sep 18.

PMID:
17936263
[PubMed - indexed for MEDLINE]
Free Article
20.

Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells.

Hart A, Papadopoulou S, Edlund H.

Dev Dyn. 2003 Oct;228(2):185-93.

PMID:
14517990
[PubMed - indexed for MEDLINE]
Free Article

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