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Results: 1 to 20 of 163

1.

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform.

Liu H, Sugiura M, Nava VE, Edsall LC, Kono K, Poulton S, Milstien S, Kohama T, Spiegel S.

J Biol Chem. 2000 Jun 30;275(26):19513-20.

PMID:
10751414
[PubMed - indexed for MEDLINE]
Free Article
2.

Molecular cloning and functional characterization of murine sphingosine kinase.

Kohama T, Olivera A, Edsall L, Nagiec MM, Dickson R, Spiegel S.

J Biol Chem. 1998 Sep 11;273(37):23722-8.

PMID:
9726979
[PubMed - indexed for MEDLINE]
Free Article
3.

Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases.

Billich A, Bornancin F, Dévay P, Mechtcheriakova D, Urtz N, Baumruker T.

J Biol Chem. 2003 Nov 28;278(48):47408-15. Epub 2003 Sep 16.

PMID:
13129923
[PubMed - indexed for MEDLINE]
Free Article
4.

Involvement of N-terminal-extended form of sphingosine kinase 2 in serum-dependent regulation of cell proliferation and apoptosis.

Okada T, Ding G, Sonoda H, Kajimoto T, Haga Y, Khosrowbeygi A, Gao S, Miwa N, Jahangeer S, Nakamura S.

J Biol Chem. 2005 Oct 28;280(43):36318-25. Epub 2005 Aug 15.

PMID:
16103110
[PubMed - indexed for MEDLINE]
Free Article
5.

Functional characterization of human sphingosine kinase-1.

Nava VE, Lacana E, Poulton S, Liu H, Sugiura M, Kono K, Milstien S, Kohama T, Spiegel S.

FEBS Lett. 2000 May 4;473(1):81-4.

PMID:
10802064
[PubMed - indexed for MEDLINE]
Free Article
6.

Human sphingosine kinase: molecular cloning, functional characterization and tissue distribution.

Melendez AJ, Carlos-Dias E, Gosink M, Allen JM, Takacs L.

Gene. 2000 Jun 13;251(1):19-26.

PMID:
10863092
[PubMed - indexed for MEDLINE]
7.

Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.

Liu H, Toman RE, Goparaju SK, Maceyka M, Nava VE, Sankala H, Payne SG, Bektas M, Ishii I, Chun J, Milstien S, Spiegel S.

J Biol Chem. 2003 Oct 10;278(41):40330-6. Epub 2003 Jun 30.

PMID:
12835323
[PubMed - indexed for MEDLINE]
Free Article
8.

Cloning and characterization of a protein kinase A anchoring protein (AKAP)-related protein that interacts with and regulates sphingosine kinase 1 activity.

Lacaná E, Maceyka M, Milstien S, Spiegel S.

J Biol Chem. 2002 Sep 6;277(36):32947-53. Epub 2002 Jun 21.

PMID:
12080051
[PubMed - indexed for MEDLINE]
Free Article
9.

Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability.

Johnson KR, Johnson KY, Becker KP, Bielawski J, Mao C, Obeid LM.

J Biol Chem. 2003 Sep 5;278(36):34541-7. Epub 2003 Jun 18.

PMID:
12815058
[PubMed - indexed for MEDLINE]
Free Article
10.

Regulation and functional roles of sphingosine kinases.

Alemany R, van Koppen CJ, Danneberg K, Ter Braak M, Meyer Zu Heringdorf D.

Naunyn Schmiedebergs Arch Pharmacol. 2007 Feb;374(5-6):413-28. Epub 2007 Jan 23. Review.

PMID:
17242884
[PubMed - indexed for MEDLINE]
11.

The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2.

Paugh SW, Payne SG, Barbour SE, Milstien S, Spiegel S.

FEBS Lett. 2003 Nov 6;554(1-2):189-93.

PMID:
14596938
[PubMed - indexed for MEDLINE]
Free Article
12.

Sphingosine kinase type 2 activation by ERK-mediated phosphorylation.

Hait NC, Bellamy A, Milstien S, Kordula T, Spiegel S.

J Biol Chem. 2007 Apr 20;282(16):12058-65. Epub 2007 Feb 20.

PMID:
17311928
[PubMed - indexed for MEDLINE]
Free Article
13.

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism.

Maceyka M, Sankala H, Hait NC, Le Stunff H, Liu H, Toman R, Collier C, Zhang M, Satin LS, Merrill AH Jr, Milstien S, Spiegel S.

J Biol Chem. 2005 Nov 4;280(44):37118-29. Epub 2005 Aug 23.

PMID:
16118219
[PubMed - indexed for MEDLINE]
Free Article
14.

Sphingosine kinases: a novel family of lipid kinases.

Liu H, Chakravarty D, Maceyka M, Milstien S, Spiegel S.

Prog Nucleic Acid Res Mol Biol. 2002;71:493-511. Review.

PMID:
12102559
[PubMed - indexed for MEDLINE]
15.

Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization.

Sugiura M, Kono K, Liu H, Shimizugawa T, Minekura H, Spiegel S, Kohama T.

J Biol Chem. 2002 Jun 28;277(26):23294-300. Epub 2002 Apr 15.

PMID:
11956206
[PubMed - indexed for MEDLINE]
Free Article
16.

Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein.

Hayashi S, Okada T, Igarashi N, Fujita T, Jahangeer S, Nakamura S.

J Biol Chem. 2002 Sep 6;277(36):33319-24. Epub 2002 Jun 20.

PMID:
12077123
[PubMed - indexed for MEDLINE]
Free Article
17.

Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells: response to cytokines.

Mastrandrea LD, Sessanna SM, Laychock SG.

Diabetes. 2005 May;54(5):1429-36.

PMID:
15855330
[PubMed - indexed for MEDLINE]
Free Article
18.

Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes.

Pitson SM, D'andrea RJ, Vandeleur L, Moretti PA, Xia P, Gamble JR, Vadas MA, Wattenberg BW.

Biochem J. 2000 Sep 1;350 Pt 2:429-41.

PMID:
10947957
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen.

Schröder M, Richter C, Juan MH, Maltusch K, Giegold O, Quintini G, Pfeilschifter JM, Huwiler A, Radeke HH.

Mol Immunol. 2011 May;48(9-10):1139-48. doi: 10.1016/j.molimm.2011.02.007. Epub 2011 Mar 23.

PMID:
21435724
[PubMed - indexed for MEDLINE]
20.

Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient.

Venkataraman K, Thangada S, Michaud J, Oo ML, Ai Y, Lee YM, Wu M, Parikh NS, Khan F, Proia RL, Hla T.

Biochem J. 2006 Aug 1;397(3):461-71.

PMID:
16623665
[PubMed - indexed for MEDLINE]
Free PMC Article

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