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Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis.

Inbal B, Shani G, Cohen O, Kissil JL, Kimchi A.

Mol Cell Biol. 2000 Feb;20(3):1044-54.


Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding.

Shani G, Henis-Korenblit S, Jona G, Gileadi O, Eisenstein M, Ziv T, Admon A, Kimchi A.

EMBO J. 2001 Mar 1;20(5):1099-113.


The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases.

Shohat G, Shani G, Eisenstein M, Kimchi A.

Biochim Biophys Acta. 2002 Nov 4;1600(1-2):45-50. Review.


rDrak1, a novel kinase related to apoptosis, is strongly expressed in active osteoclasts and induces apoptosis.

Kojima H, Nemoto A, Uemura T, Honma R, Ogura M, Liu Y.

J Biol Chem. 2001 Jun 1;276(22):19238-43. Epub 2001 Mar 14.


New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform.

Shoval Y, Berissi H, Kimchi A, Pietrokovski S.

PLoS One. 2011 Mar 8;6(2):e17344. doi: 10.1371/journal.pone.0017344.


ZIP kinase, a novel serine/threonine kinase which mediates apoptosis.

Kawai T, Matsumoto M, Takeda K, Sanjo H, Akira S.

Mol Cell Biol. 1998 Mar;18(3):1642-51.


Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions.

Shani G, Marash L, Gozuacik D, Bialik S, Teitelbaum L, Shohat G, Kimchi A.

Mol Cell Biol. 2004 Oct;24(19):8611-26.


The pro-apoptotic function of death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism.

Shohat G, Spivak-Kroizman T, Cohen O, Bialik S, Shani G, Berrisi H, Eisenstein M, Kimchi A.

J Biol Chem. 2001 Dec 14;276(50):47460-7. Epub 2001 Sep 28.


Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity.

Kawai T, Nomura F, Hoshino K, Copeland NG, Gilbert DJ, Jenkins NA, Akira S.

Oncogene. 1999 Jun 10;18(23):3471-80.


Cloning and characterization of Dlk, a novel serine/threonine kinase that is tightly associated with chromatin and phosphorylates core histones.

Kögel D, Plöttner O, Landsberg G, Christian S, Scheidtmann KH.

Oncogene. 1998 Nov 19;17(20):2645-54.


The regulation of death-associated protein (DAP) kinase in apoptosis.

Shohat G, Spivak-Kroizman T, Eisenstein M, Kimchi A.

Eur Cytokine Netw. 2002 Oct-Dec;13(4):398-400. Review.


Regulatory mechanism of Ca2+/calmodulin-dependent protein kinase kinase.

Tokumitsu H, Muramatsu Ma, Ikura M, Kobayashi R.

J Biol Chem. 2000 Jun 30;275(26):20090-5.


Substrate recognition by Ca2+/Calmodulin-dependent protein kinase kinase. Role of the arg-pro-rich insert domain.

Tokumitsu H, Takahashi N, Eto K, Yano S, Soderling TR, Muramatsu M.

J Biol Chem. 1999 May 28;274(22):15803-10.


An extended conformation of calmodulin induces interactions between the structural domains of adenylyl cyclase from Bacillus anthracis to promote catalysis.

Drum CL, Yan SZ, Sarac R, Mabuchi Y, Beckingham K, Bohm A, Grabarek Z, Tang WJ.

J Biol Chem. 2000 Nov 17;275(46):36334-40.

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