Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 172

1.

Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes.

Wienkers LC, Allievi C, Hauer MJ, Wynalda MA.

Drug Metab Dispos. 1999 Nov;27(11):1334-40.

PMID:
10534319
[PubMed - indexed for MEDLINE]
Free Article
2.

Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.

Rodrigues AD, Roberts EM, Mulford DJ, Yao Y, Ouellet D.

Drug Metab Dispos. 1997 May;25(5):623-30.

PMID:
9152603
[PubMed - indexed for MEDLINE]
Free Article
3.

Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.

Niwa T, Shiraga T, Mitani Y, Terakawa M, Tokuma Y, Kagayama A.

Drug Metab Dispos. 2000 Sep;28(9):1128-34.

PMID:
10950860
[PubMed - indexed for MEDLINE]
Free Article
4.

Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor.

Tang C, Shou M, Mei Q, Rushmore TH, Rodrigues AD.

J Pharmacol Exp Ther. 2000 May;293(2):453-9.

PMID:
10773015
[PubMed - indexed for MEDLINE]
Free Article
5.

Reboxetine and cytochrome P450--comparison with paroxetine treatment in humans.

Kuhn UD, Kirsch M, Merkel U, Eberhardt AM, Wenda B, Maurer I, Härtter S, Hiemke C, Volz HP, Balogh A.

Int J Clin Pharmacol Ther. 2007 Jan;45(1):36-46.

PMID:
17256449
[PubMed - indexed for MEDLINE]
6.

Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs.

Nakajima M, Nakamura S, Tokudome S, Shimada N, Yamazaki H, Yokoi T.

Drug Metab Dispos. 1999 Dec;27(12):1381-91.

PMID:
10570018
[PubMed - indexed for MEDLINE]
Free Article
7.

Species difference in stereoselective involvement of CYP3A in the mono-N-dealkylation of disopyramide.

Zhang L, Fitzloff JF, Engel LC, Cook CS.

Xenobiotica. 2001 Feb;31(2):73-83.

PMID:
11407536
[PubMed - indexed for MEDLINE]
8.

Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro.

Wang JS, DeVane CL.

Drug Metab Dispos. 2003 Jun;31(6):742-7.

PMID:
12756206
[PubMed - indexed for MEDLINE]
Free Article
9.

Oxidation of the novel oxazolidinone antibiotic linezolid in human liver microsomes.

Wynalda MA, Hauer MJ, Wienkers LC.

Drug Metab Dispos. 2000 Sep;28(9):1014-7.

PMID:
10950842
[PubMed - indexed for MEDLINE]
Free Article
10.

The interactions of a selective protein kinase C beta inhibitor with the human cytochromes P450.

Ring BJ, Gillespie JS, Binkley SN, Campanale KM, Wrighton SA.

Drug Metab Dispos. 2002 Sep;30(9):957-61.

PMID:
12167559
[PubMed - indexed for MEDLINE]
Free Article
11.

Characterization of the human hepatic cytochromes P450 involved in the in vitro oxidation of clozapine.

Tugnait M, Hawes EM, McKay G, Eichelbaum M, Midha KK.

Chem Biol Interact. 1999 Apr 1;118(2):171-89.

PMID:
10359460
[PubMed - indexed for MEDLINE]
12.

Identification of CYP3A4 as the enzyme involved in the mono-N-dealkylation of disopyramide enantiomers in humans.

Echizen H, Tanizaki M, Tatsuno J, Chiba K, Berwick T, Tani M, Gonzalez FJ, Ishizaki T.

Drug Metab Dispos. 2000 Aug;28(8):937-44.

PMID:
10901704
[PubMed - indexed for MEDLINE]
Free Article
13.

Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.

Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.

Xenobiotica. 2000 Oct;30(10):955-69.

PMID:
11315104
[PubMed - indexed for MEDLINE]
14.

Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.

Lalovic B, Phillips B, Risler LL, Howald W, Shen DD.

Drug Metab Dispos. 2004 Apr;32(4):447-54.

PMID:
15039299
[PubMed - indexed for MEDLINE]
Free Article
15.

Enantiomer/enantiomer interactions between the S- and R- isomers of omeprazole in human cytochrome P450 enzymes: major role of CYP2C19 and CYP3A4.

Li XQ, Weidolf L, Simonsson R, Andersson TB.

J Pharmacol Exp Ther. 2005 Nov;315(2):777-87. Epub 2005 Aug 10.

PMID:
16093273
[PubMed - indexed for MEDLINE]
Free Article
16.

In vitro metabolism of chloroquine: identification of CYP2C8, CYP3A4, and CYP2D6 as the main isoforms catalyzing N-desethylchloroquine formation.

Projean D, Baune B, Farinotti R, Flinois JP, Beaune P, Taburet AM, Ducharme J.

Drug Metab Dispos. 2003 Jun;31(6):748-54.

PMID:
12756207
[PubMed - indexed for MEDLINE]
Free Article
17.

In vitro metabolism of clindamycin in human liver and intestinal microsomes.

Wynalda MA, Hutzler JM, Koets MD, Podoll T, Wienkers LC.

Drug Metab Dispos. 2003 Jul;31(7):878-87.

PMID:
12814964
[PubMed - indexed for MEDLINE]
Free Article
18.

Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation.

Jones DR, Gorski JC, Hamman MA, Mayhew BS, Rider S, Hall SD.

J Pharmacol Exp Ther. 1999 Sep;290(3):1116-25.

PMID:
10454485
[PubMed - indexed for MEDLINE]
Free Article
19.

Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.

Khojasteh-Bakht SC, Rossulek MI, Fouda HG, Prakash C.

Xenobiotica. 2003 Dec;33(12):1201-10.

PMID:
14742142
[PubMed - indexed for MEDLINE]
20.

Identification of human cytochrome P-450 isoforms involved in metabolism of R(+)- and S(-)-gallopamil: utility of in vitro disappearance rate.

Suzuki A, Iida I, Tanaka F, Akimoto M, Fukushima K, Tani M, Ishizaki T, Chiba K.

Drug Metab Dispos. 1999 Nov;27(11):1254-9.

PMID:
10534309
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk