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Items: 1 to 20 of 110

1.

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt.

Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC.

Nature. 1999 Jun 10;399(6736):597-601. Erratum in: Nature 1999 Aug 19;400(6746):792.

2.

High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases.

Mineo C, Yuhanna IS, Quon MJ, Shaul PW.

J Biol Chem. 2003 Mar 14;278(11):9142-9. Epub 2003 Jan 2.

3.

Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

Montagnani M, Chen H, Barr VA, Quon MJ.

J Biol Chem. 2001 Aug 10;276(32):30392-8. Epub 2001 Jun 11.

4.

Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase.

Zou MH, Hou XY, Shi CM, Nagata D, Walsh K, Cohen RA.

J Biol Chem. 2002 Sep 6;277(36):32552-7. Epub 2002 Jul 9.

6.
7.

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation.

Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM.

Nature. 1999 Jun 10;399(6736):601-5.

PMID:
10376603
8.

The Akt kinase signals directly to endothelial nitric oxide synthase.

Michell BJ, Griffiths JE, Mitchelhill KI, Rodriguez-Crespo I, Tiganis T, Bozinovski S, de Montellano PR, Kemp BE, Pearson RB.

Curr Biol. 1999 Jul 29-Aug 12;9(15):845-8.

12.

Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells.

Haynes MP, Sinha D, Russell KS, Collinge M, Fulton D, Morales-Ruiz M, Sessa WC, Bender JR.

Circ Res. 2000 Oct 13;87(8):677-82.

13.

Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen.

Haynes MP, Li L, Sinha D, Russell KS, Hisamoto K, Baron R, Collinge M, Sessa WC, Bender JR.

J Biol Chem. 2003 Jan 24;278(4):2118-23. Epub 2002 Nov 12.

16.

Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A.

Boo YC, Sorescu G, Boyd N, Shiojima I, Walsh K, Du J, Jo H.

J Biol Chem. 2002 Feb 1;277(5):3388-96. Epub 2001 Nov 29.

17.

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ.

J Biol Chem. 2003 Nov 7;278(45):45021-6. Epub 2003 Aug 27.

19.

Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells.

Morales-Ruiz M, Lee MJ, Zöllner S, Gratton JP, Scotland R, Shiojima I, Walsh K, Hla T, Sessa WC.

J Biol Chem. 2001 Jun 1;276(22):19672-7. Epub 2001 Mar 6.

20.

Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells.

Ming XF, Viswambharan H, Barandier C, Ruffieux J, Kaibuchi K, Rusconi S, Yang Z.

Mol Cell Biol. 2002 Dec;22(24):8467-77.

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