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Results: 1 to 20 of 130

1.

Gö 6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase.

Behrens MM, Strasser U, Choi DW.

J Neurochem. 1999 Mar;72(3):919-24.

PMID:
10037462
[PubMed - indexed for MEDLINE]
2.

CEP-751 inhibits TRK receptor tyrosine kinase activity in vitro exhibits anti-tumor activity.

Camoratto AM, Jani JP, Angeles TS, Maroney AC, Sanders CY, Murakata C, Neff NT, Vaught JL, Isaacs JT, Dionne CA.

Int J Cancer. 1997 Aug 7;72(4):673-9.

PMID:
9259409
[PubMed - indexed for MEDLINE]
3.

Suppression of p140trkA does not abolish nerve growth factor-mediated rescue of serum-free PC12 cells.

Taglialatela G, Hibbert CJ, Hutton LA, Werrbach-Perez K, Perez-Polo JR.

J Neurochem. 1996 May;66(5):1826-35.

PMID:
8780007
[PubMed - indexed for MEDLINE]
4.

The staurosporine-like compound L-753,000 (NB-506) potentiates the neurotrophic effects of neurotrophin-3 by acting selectively at the TrkA receptor.

Pollack S, Young L, Bilsland J, Wilkie N, Ellis S, Hefti F, Broughton H, Harper S.

Mol Pharmacol. 1999 Jul;56(1):185-95.

PMID:
10385700
[PubMed - indexed for MEDLINE]
Free Article
5.

Interleukin-6 induces expression of peripherin and cooperates with Trk receptor signaling to promote neuronal differentiation in PC12 cells.

Sterneck E, Kaplan DR, Johnson PF.

J Neurochem. 1996 Oct;67(4):1365-74.

PMID:
8858917
[PubMed - indexed for MEDLINE]
6.

Delta-protein kinase C phosphorylation parallels inhibition of nerve growth factor-induced differentiation independent of changes in Trk A and MAP kinase signalling in PC12 cells.

Wooten MW, Seibenhener ML, Heikkila JE, Mischak H.

Cell Signal. 1998 Apr;10(4):265-76.

PMID:
9617484
[PubMed - indexed for MEDLINE]
7.

K-252b selectively potentiates cellular actions and trk tyrosine phosphorylation mediated by neurotrophin-3.

Knüsel B, Kaplan DR, Winslow JW, Rosenthal A, Burton LE, Beck KD, Rabin S, Nikolics K, Hefti F.

J Neurochem. 1992 Aug;59(2):715-22.

PMID:
1629741
[PubMed - indexed for MEDLINE]
8.

Inhibition of phosphorylation of TrkB and TrkC and their signal transduction by alpha2-macroglobulin.

Hu YQ, Koo PH.

J Neurochem. 1998 Jul;71(1):213-20.

PMID:
9648868
[PubMed - indexed for MEDLINE]
9.

Signal transduction pathways through TRK-A and TRK-B receptors in human neuroblastoma cells.

Sugimoto T, Kuroda H, Horii Y, Moritake H, Tanaka T, Hattori S.

Jpn J Cancer Res. 2001 Feb;92(2):152-60.

PMID:
11223544
[PubMed - indexed for MEDLINE]
10.

p75 reduces TrkB tyrosine autophosphorylation in response to brain-derived neurotrophic factor and neurotrophin 4/5.

Vesa J, Kruttgen A, Shooter EM.

J Biol Chem. 2000 Aug 11;275(32):24414-20.

PMID:
10825163
[PubMed - indexed for MEDLINE]
Free Article
11.

Expression of TRK-T1 oncogene induces differentiation of PC12 cells.

Greco A, Orlandi R, Mariani C, Miranda C, Borrello MG, Cattaneo A, Pagliardini S, Pierotti MA.

Cell Growth Differ. 1993 Jul;4(7):539-46.

PMID:
8398895
[PubMed - indexed for MEDLINE]
Free Article
12.

Extended ceramide exposure activates the trkA receptor by increasing receptor homodimer formation.

MacPhee I, Barker PA.

J Neurochem. 1999 Apr;72(4):1423-30.

PMID:
10098845
[PubMed - indexed for MEDLINE]
13.

K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors.

Tapley P, Lamballe F, Barbacid M.

Oncogene. 1992 Feb;7(2):371-81.

PMID:
1312698
[PubMed - indexed for MEDLINE]
14.

4-Methylcatechol stimulates phosphorylation of Trk family neurotrophin receptors and MAP kinases in cultured rat cortical neurons.

Sometani A, Nomoto H, Nitta A, Furukawa Y, Furukawa S.

J Neurosci Res. 2002 Nov 1;70(3):335-9.

PMID:
12391593
[PubMed - indexed for MEDLINE]
15.

Ligand-induced down-regulation of Trk messenger RNA, protein and tyrosine phosphorylation in rat cortical neurons.

Knusel B, Gao H, Okazaki T, Yoshida T, Mori N, Hefti F, Kaplan DR.

Neuroscience. 1997 Jun;78(3):851-62.

PMID:
9153663
[PubMed - indexed for MEDLINE]
16.

Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways.

Barnabé-Heider F, Miller FD.

J Neurosci. 2003 Jun 15;23(12):5149-60.

PMID:
12832539
[PubMed - indexed for MEDLINE]
Free Article
17.

Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons.

Araki T, Yamada M, Ohnishi H, Sano S, Uetsuki T, Hatanaka H.

J Neurochem. 2000 Feb;74(2):659-68.

PMID:
10646517
[PubMed - indexed for MEDLINE]
18.

The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.

Perez-Pinera P, Hernandez T, García-Suárez O, de Carlos F, Germana A, Del Valle M, Astudillo A, Vega JA.

Mol Cell Biochem. 2007 Jan;295(1-2):19-26. Epub 2006 Jul 22.

PMID:
16862449
[PubMed - indexed for MEDLINE]
19.

Nerve growth factor signal transduction in mature pig oligodendrocytes.

Althaus HH, Hempel R, Klöppner S, Engel J, Schmidt-Schultz T, Kruska L, Heumann R.

J Neurosci Res. 1997 Dec 1;50(5):729-42.

PMID:
9418961
[PubMed - indexed for MEDLINE]
20.

Sustained in vivo regression of Dunning H rat prostate cancers treated with combinations of androgen ablation and Trk tyrosine kinase inhibitors, CEP-751 (KT-6587) or CEP-701 (KT-5555).

George DJ, Dionne CA, Jani J, Angeles T, Murakata C, Lamb J, Isaacs JT.

Cancer Res. 1999 May 15;59(10):2395-401.

PMID:
10344749
[PubMed - indexed for MEDLINE]
Free Article

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