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Results: 1 to 20 of 349

PubMed (Weighted) Links for Protein (Select 47157322)

1.

Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β-dependent vascular endothelial cadherin tyrosine phosphorylation.

Haidari M, Zhang W, Willerson JT, Dixon RA.

Cardiovasc Diabetol. 2014 Jul 15;13:112. doi: 10.1186/1475-2840-13-112.

2.

Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-ßI and prooxidant enzyme NADPH oxidase.

Shao B, Bayraktutan U.

Redox Biol. 2014 May 28;2:694-701. doi: 10.1016/j.redox.2014.05.005. eCollection 2014.

3.

PKCβII acts downstream of chemoattractant receptors and mTORC2 to regulate cAMP production and myosin II activity in neutrophils.

Liu L, Gritz D, Parent CA.

Mol Biol Cell. 2014 May;25(9):1446-57. doi: 10.1091/mbc.E14-01-0037. Epub 2014 Mar 5.

4.

Protein kinase C isoforms in atherosclerosis: pro- or anti-inflammatory?

Fan HC, Fernández-Hernando C, Lai JH.

Biochem Pharmacol. 2014 Mar 15;88(2):139-49. doi: 10.1016/j.bcp.2014.01.006. Epub 2014 Jan 16. Review.

PMID:
24440741
5.

Genomewide RNAi screen identifies protein kinase Cb and new members of mitogen-activated protein kinase pathway as regulators of melanoma cell growth and metastasis.

Schönherr M, Bhattacharya A, Kottek T, Szymczak S, Köberle M, Wickenhauser C, Siebolts U, Saalbach A, Koczan D, Magin TM, Simon JC, Kunz M.

Pigment Cell Melanoma Res. 2014 May;27(3):418-30. doi: 10.1111/pcmr.12216. Epub 2014 Jan 31.

PMID:
24406113
6.

PKC-β exacerbates in vitro brain barrier damage in hyperglycemic settings via regulation of RhoA/Rho-kinase/MLC2 pathway.

Srivastava K, Shao B, Bayraktutan U.

J Cereb Blood Flow Metab. 2013 Dec;33(12):1928-36. doi: 10.1038/jcbfm.2013.151. Epub 2013 Aug 21.

7.

Modulation of pancreatic tumor potential by overexpression of protein kinase C β1.

Cirigliano SM, Mauro LV, Grossoni VC, Colombo LL, Diament MJ, Kazanietz MG, Bal de Kier Joffé ED, Puricelli LI, Urtreger AJ.

Pancreas. 2013 Oct;42(7):1060-9. doi: 10.1097/MPA.0b013e31828fd141.

PMID:
23695799
8.

Hyperglycaemia promotes cerebral barrier dysfunction through activation of protein kinase C-β.

Shao B, Bayraktutan U.

Diabetes Obes Metab. 2013 Nov;15(11):993-9. doi: 10.1111/dom.12120. Epub 2013 May 21.

PMID:
23617822
9.

A polymorphism in the protein kinase C gene PRKCB is associated with α2-adrenoceptor-mediated vasoconstriction.

Posti JP, Salo P, Ruohonen S, Valve L, Muszkat M, Sofowora GG, Kurnik D, Stein CM, Perola M, Scheinin M, Snapir A.

Pharmacogenet Genomics. 2013 Mar;23(3):127-34. doi: 10.1097/FPC.0b013e32835d247f.

10.

Protein kinase C-β contributes to impaired endothelial insulin signaling in humans with diabetes mellitus.

Tabit CE, Shenouda SM, Holbrook M, Fetterman JL, Kiani S, Frame AA, Kluge MA, Held A, Dohadwala MM, Gokce N, Farb MG, Rosenzweig J, Ruderman N, Vita JA, Hamburg NM.

Circulation. 2013 Jan 1;127(1):86-95. doi: 10.1161/CIRCULATIONAHA.112.127514. Epub 2012 Nov 30.

11.

PRKCB is associated with calcineurin inhibitor-induced renal dysfunction in heart transplant recipients.

Lachance K, Barhdadi A, Mongrain I, Normand V, Zakrzewski M, Leblanc MH, Racine N, Carrier M, Ducharme A, Turgeon J, Dubé MP, Phillips MS, White M, de Denus S.

Pharmacogenet Genomics. 2012 May;22(5):336-43. doi: 10.1097/FPC.0b013e3283510a35.

PMID:
22322241
12.

Negative feedback regulation of Gq signaling by protein kinase C is disrupted by diacylglycerol kinase ζ in COS-7 cells.

Litosch I.

Biochem Biophys Res Commun. 2012 Jan 20;417(3):956-60. doi: 10.1016/j.bbrc.2011.12.037. Epub 2011 Dec 16.

PMID:
22197823
14.

Follow-up study identifies two novel susceptibility loci PRKCB and 8p11.21 for systemic lupus erythematosus.

Sheng YJ, Gao JP, Li J, Han JW, Xu Q, Hu WL, Pan TM, Cheng YL, Yu ZY, Ni C, Yao S, He CF, Liu YS, Li Y, Ge HM, Xiao FL, Sun LD, Yang S, Zhang XJ.

Rheumatology (Oxford). 2011 Apr;50(4):682-8. doi: 10.1093/rheumatology/keq313. Epub 2010 Dec 6.

15.

Specific inhibition of protein kinase Cbeta expression by antisense RNA affects the activation of Jurkat T lymphoma cells.

Cervino MC, Lopez-Lago MA, Vinuela JE, Barja P.

J Biol Regul Homeost Agents. 2010 Jul-Sep;24(3):273-85.

PMID:
20846475
16.

Genetic variants of the protein kinase C-beta 1 gene and development of end-stage renal disease in patients with type 2 diabetes.

Ma RC, Tam CH, Wang Y, Luk AO, Hu C, Yang X, Lam V, Chan AW, Ho JS, Chow CC, Tong PC, Jia W, Ng MC, So WY, Chan JC.

JAMA. 2010 Aug 25;304(8):881-9. doi: 10.1001/jama.2010.1191.

PMID:
20736472
17.

Protein kinase C-beta gene variants, pathway activation, and enzastaurin activity in lung cancer.

Lee SH, Chen T, Zhou J, Hofmann J, Bepler G.

Clin Lung Cancer. 2010 May;11(3):169-75. doi: 10.3816/CLC.2010.n.021.

18.

Differential subcellular expression of protein kinase C betaII in breast cancer: correlation with breast cancer subtypes.

Gökmen-Polar Y, Mehta R, Tuzmen S, Mousses S, Thorat MA, Sanders KL, Turbin D, Leung S, Huntsman DG, Sledge GW Jr, Badve S.

Breast Cancer Res Treat. 2010 Nov;124(2):327-35. doi: 10.1007/s10549-010-0733-2. Epub 2010 Jan 23.

PMID:
20099025
19.

Functional alterations in protein kinase C beta II expression in melanoma.

Voris JP, Sitailo LA, Rahn HR, Defnet A, Gerds AT, Sprague R, Yadav V, Caroline Le Poole I, Denning MF.

Pigment Cell Melanoma Res. 2010 Apr;23(2):216-24. doi: 10.1111/j.1755-148X.2009.00664.x. Epub 2009 Dec 14.

PMID:
20015121
20.

Protein kinase Cbeta modulates ligand-induced cell surface death receptor accumulation: a mechanistic basis for enzastaurin-death ligand synergy.

Meng XW, Heldebrant MP, Flatten KS, Loegering DA, Dai H, Schneider PA, Gomez TS, Peterson KL, Trushin SA, Hess AD, Smith BD, Karp JE, Billadeau DD, Kaufmann SH.

J Biol Chem. 2010 Jan 8;285(2):888-902. doi: 10.1074/jbc.M109.057638. Epub 2009 Nov 3.

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