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Results: 1 to 20 of 92

PubMed (RefSeq) Links for Protein (Select 86991432)

1.

14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2.

Xu J, Acharya S, Sahin O, Zhang Q, Saito Y, Yao J, Wang H, Li P, Zhang L, Lowery FJ, Kuo WL, Xiao Y, Ensor J, Sahin AA, Zhang XH, Hung MC, Zhang JD, Yu D.

Cancer Cell. 2015 Feb 9;27(2):177-92. doi: 10.1016/j.ccell.2014.11.025.

PMID:
25670079
2.

Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion.

Nagao-Kitamoto H, Setoguchi T, Kitamoto S, Nakamura S, Tsuru A, Nagata M, Nagano S, Ishidou Y, Yokouchi M, Kitajima S, Yoshioka T, Maeda S, Yonezawa S, Komiya S.

Cancer Lett. 2015 Jan 28;356(2 Pt B):855-61. doi: 10.1016/j.canlet.2014.10.042. Epub 2014 Nov 11.

PMID:
25449781
3.

Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.

Johnson RW, Merkel AR, Page JM, Ruppender NS, Guelcher SA, Sterling JA.

Clin Exp Metastasis. 2014 Dec;31(8):945-59. doi: 10.1007/s10585-014-9682-1. Epub 2014 Oct 31.

PMID:
25359619
4.

SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer.

Zeng C, Wang Y, Lu Q, Chen J, Zhang J, Liu T, Lv N, Luo S.

J Exp Clin Cancer Res. 2014 Sep 11;33:75. doi: 10.1186/s13046-014-0075-8.

5.

Determinants of Gli2 co-activation of wildtype and naturally truncated androgen receptors.

Li N, Chen M, Truong S, Yan C, Buttyan R.

Prostate. 2014 Oct;74(14):1400-10. doi: 10.1002/pros.22855. Epub 2014 Aug 11.

PMID:
25132524
6.

ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2.

Ram Kumar RM, Betz MM, Robl B, Born W, Fuchs B.

BMC Cancer. 2014 Aug 1;14:559. doi: 10.1186/1471-2407-14-559.

7.

GLI2 is a novel therapeutic target for metastasis of osteosarcoma.

Nagao-Kitamoto H, Nagata M, Nagano S, Kitamoto S, Ishidou Y, Yamamoto T, Nakamura S, Tsuru A, Abematsu M, Fujimoto Y, Yokouchi M, Kitajima S, Yoshioka T, Maeda S, Yonezawa S, Komiya S, Setoguchi T.

Int J Cancer. 2015 Mar 15;136(6):1276-84. doi: 10.1002/ijc.29107. Epub 2014 Aug 8.

PMID:
25082385
8.

Pathogenic mutations in GLI2 cause a specific phenotype that is distinct from holoprosencephaly.

Bear KA, Solomon BD, Antonini S, Arnhold IJ, França MM, Gerkes EH, Grange DK, Hadley DW, Jääskeläinen J, Paulo SS, Rump P, Stratakis CA, Thompson EM, Willis M, Winder TL, Jorge AA, Roessler E, Muenke M.

J Med Genet. 2014 Jun;51(6):413-8. doi: 10.1136/jmedgenet-2013-102249. Epub 2014 Apr 17.

PMID:
24744436
9.

GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis.

Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh MT, Lu YJ, Philpott MP.

Cell Death Dis. 2014 Jan 30;5:e1028. doi: 10.1038/cddis.2013.535.

10.

Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.

Huang L, Walter V, Hayes DN, Onaitis M.

Clin Cancer Res. 2014 Mar 15;20(6):1566-75. doi: 10.1158/1078-0432.CCR-13-2195. Epub 2014 Jan 14.

11.

Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells.

Piirsoo A, Kasak L, Kauts ML, Loog M, Tints K, Uusen P, Neuman T, Piirsoo M.

Biochim Biophys Acta. 2014 Apr;1843(4):703-14. doi: 10.1016/j.bbamcr.2014.01.003. Epub 2014 Jan 10.

12.

Hedgehog/GLI signaling activates suppressor of cytokine signaling 1 (SOCS1) in epidermal and neural tumor cells.

Laner-Plamberger S, Wolff F, Kaser-Eichberger A, Swierczynski S, Hauser-Kronberger C, Frischauf AM, Eichberger T.

PLoS One. 2013 Sep 10;8(9):e75317. doi: 10.1371/journal.pone.0075317. eCollection 2013.

13.

GLI2 cooperates with ZEB1 for transcriptional repression of CDH1 expression in human melanoma cells.

Perrot CY, Gilbert C, Marsaud V, Postigo A, Javelaud D, Mauviel A.

Pigment Cell Melanoma Res. 2013 Nov;26(6):861-73. doi: 10.1111/pcmr.12149. Epub 2013 Aug 12.

PMID:
23890107
14.

The oncogenic GLI transcription factors facilitate keratinocyte survival and transformation upon exposure to genotoxic agents.

Harrison W, Cochrane B, Neill G, Philpott M.

Oncogene. 2014 May 8;33(19):2432-40. doi: 10.1038/onc.2013.199. Epub 2013 Jun 24.

PMID:
23792444
15.

Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy.

Coni S, Antonucci L, D'Amico D, Di Magno L, Infante P, De Smaele E, Giannini G, Di Marcotullio L, Screpanti I, Gulino A, Canettieri G.

PLoS One. 2013 Jun 6;8(6):e65718. doi: 10.1371/journal.pone.0065718. Print 2013.

16.

The prognostic significance and therapeutic potential of hedgehog signaling in intrahepatic cholangiocellular carcinoma.

Tang L, Tan YX, Jiang BG, Pan YF, Li SX, Yang GZ, Wang M, Wang Q, Zhang J, Zhou WP, Dong LW, Wang HY.

Clin Cancer Res. 2013 Apr 15;19(8):2014-24. doi: 10.1158/1078-0432.CCR-12-0349. Epub 2013 Mar 14.

17.

Normal exon copy number of the GLI2 and GLI3 genes in patients with esophageal atresia.

Bednarczyk D, Smigiel R, Patkowski D, Laczmanska I, Lebioda A, Laczmanski L, Sasiadek MM.

Dis Esophagus. 2013 Sep-Oct;26(7):678-81. doi: 10.1111/dote.12036. Epub 2013 Feb 26.

PMID:
23442119
18.

Functional characterization of a heterozygous GLI2 missense mutation in patients with multiple pituitary hormone deficiency.

Flemming GM, Klammt J, Ambler G, Bao Y, Blum WF, Cowell C, Donaghue K, Howard N, Kumar A, Sanchez J, Stobbe H, Pfäffle RW.

J Clin Endocrinol Metab. 2013 Mar;98(3):E567-75. doi: 10.1210/jc.2012-3224. Epub 2013 Feb 13.

19.

Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.

Lee SJ, Do IG, Lee J, Kim KM, Jang J, Sohn I, Kang WK.

Target Oncol. 2013 Dec;8(4):271-80. doi: 10.1007/s11523-013-0253-1. Epub 2013 Feb 1.

PMID:
23371028
20.

Expression of glioma-associated oncogene 2 (Gli 2) is correlated with poor prognosis in patients with hepatocellular carcinoma undergoing hepatectomy.

Zhang D, Cao L, Li Y, Lu H, Yang X, Xue P.

World J Surg Oncol. 2013 Jan 29;11:25. doi: 10.1186/1477-7819-11-25.

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