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Results: 1 to 20 of 194

1.

Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect.

Wang WH, Zhang C, Lin DH, Wang L, Graves JP, Zeldin DC, Capdevila JH.

Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F453-60. doi: 10.1152/ajprenal.00123.2014. Epub 2014 Jun 25.

PMID:
24966089
[PubMed - indexed for MEDLINE]
2.

The biological actions of 11,12-epoxyeicosatrienoic acid in endothelial cells are specific to the R/S-enantiomer and require the G(s) protein.

Ding Y, Frömel T, Popp R, Falck JR, Schunck WH, Fleming I.

J Pharmacol Exp Ther. 2014 Jul;350(1):14-21. doi: 10.1124/jpet.114.214254. Epub 2014 Apr 24.

PMID:
24763066
[PubMed - indexed for MEDLINE]
3.

Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart.

Amara IE, Elshenawy OH, Abdelrady M, El-Kadi AO.

Toxicol Lett. 2014 Apr 7;226(1):53-62. doi: 10.1016/j.toxlet.2014.01.025. Epub 2014 Jan 25.

PMID:
24472606
[PubMed - indexed for MEDLINE]
4.
5.

Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy.

Althurwi HN, Elshenawy OH, El-Kadi AO.

J Cardiovasc Pharmacol. 2014 Feb;63(2):167-77. doi: 10.1097/FJC.0000000000000036.

PMID:
24157956
[PubMed - indexed for MEDLINE]
6.

CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure.

Wang X, Ni L, Yang L, Duan Q, Chen C, Edin ML, Zeldin DC, Wang DW.

Mol Pharmacol. 2014 Jan;85(1):105-15. doi: 10.1124/mol.113.087122. Epub 2013 Oct 21.

PMID:
24145329
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Epoxyeicosatrienoic acids prevent cisplatin-induced renal apoptosis through a p38 mitogen-activated protein kinase-regulated mitochondrial pathway.

Liu Y, Lu X, Nguyen S, Olson JL, Webb HK, Kroetz DL.

Mol Pharmacol. 2013 Dec;84(6):925-34. doi: 10.1124/mol.113.088302. Epub 2013 Oct 3.

PMID:
24092818
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inducible CYP2J2 and its product 11,12-EET promotes bacterial phagocytosis: a role for CYP2J2 deficiency in the pathogenesis of Crohn's disease?

Bystrom J, Thomson SJ, Johansson J, Edin ML, Zeldin DC, Gilroy DW, Smith AM, Bishop-Bailey D.

PLoS One. 2013 Sep 13;8(9):e75107. doi: 10.1371/journal.pone.0075107. eCollection 2013.

PMID:
24058654
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity.

Khan MA, Liu J, Kumar G, Skapek SX, Falck JR, Imig JD.

FASEB J. 2013 Aug;27(8):2946-56. doi: 10.1096/fj.12-218040. Epub 2013 Apr 19. Erratum in: FASEB J. 2014 Jan;28(1):520.

PMID:
23603837
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Involvement of cytochrome epoxygenase metabolites in cutaneous postocclusive hyperemia in humans.

Cracowski JL, Gaillard-Bigot F, Cracowski C, Sors C, Roustit M, Millet C.

J Appl Physiol (1985). 2013 Jan 15;114(2):245-51. doi: 10.1152/japplphysiol.01085.2012. Epub 2012 Nov 21.

PMID:
23172029
[PubMed - indexed for MEDLINE]
Free Article
11.

Soluble epoxide hydrolase disruption as therapeutic target for wound healing.

Sander AL, Sommer K, Neumayer T, Fleming I, Marzi I, Barker JH, Frank J, Jakob H.

J Surg Res. 2013 Jun 15;182(2):362-7. doi: 10.1016/j.jss.2012.10.034. Epub 2012 Oct 30.

PMID:
23122666
[PubMed - indexed for MEDLINE]
12.

11,12-EET stimulates the association of BK channel α and β(1) subunits in mitochondria to induce pulmonary vasoconstriction.

Loot AE, Moneke I, Keserü B, Oelze M, Syzonenko T, Daiber A, Fleming I.

PLoS One. 2012;7(9):e46065. doi: 10.1371/journal.pone.0046065. Epub 2012 Sep 24.

PMID:
23029390
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Upregulation of cytochrome P450 2J3/11,12-epoxyeicosatrienoic acid inhibits apoptosis in neonatal rat cardiomyocytes by a caspase-dependent pathway.

Wang HX, Zhang DM, Zeng XJ, Mu J, Yang H, Lu LQ, Zhang LK.

Cytokine. 2012 Nov;60(2):360-8. doi: 10.1016/j.cyto.2012.04.029. Epub 2012 Jun 18.

PMID:
22717287
[PubMed - indexed for MEDLINE]
14.

Epoxyeicosatrienoic acids are involved in the C(70) fullerene derivative-induced control of allergic asthma.

Norton SK, Wijesinghe DS, Dellinger A, Sturgill J, Zhou Z, Barbour S, Chalfant C, Conrad DH, Kepley CL.

J Allergy Clin Immunol. 2012 Sep;130(3):761-769.e2. doi: 10.1016/j.jaci.2012.04.023. Epub 2012 Jun 2.

PMID:
22664166
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Role of PI3Kα and sarcolemmal ATP-sensitive potassium channels in epoxyeicosatrienoic acid mediated cardioprotection.

Batchu SN, Chaudhary KR, El-Sikhry H, Yang W, Light PE, Oudit GY, Seubert JM.

J Mol Cell Cardiol. 2012 Jul;53(1):43-52. doi: 10.1016/j.yjmcc.2012.04.008. Epub 2012 Apr 27.

PMID:
22561102
[PubMed - indexed for MEDLINE]
16.

11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries.

Bukhari IA, Shah AJ, Gauthier KM, Walsh KA, Koduru SR, Imig JD, Falck JR, Campbell WB.

Am J Physiol Heart Circ Physiol. 2012 Apr 15;302(8):H1574-83. doi: 10.1152/ajpheart.01122.2011. Epub 2012 Feb 3.

PMID:
22307677
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

P-450-dependent epoxygenase pathway of arachidonic acid is involved in myeloma-induced angiogenesis of endothelial cells.

Shao J, Li Q, Wang H, Liu F, Jiang J, Zhu X, Chen Z, Zou P.

J Huazhong Univ Sci Technolog Med Sci. 2011 Oct;31(5):596-601. doi: 10.1007/s11596-011-0567-0. Epub 2011 Oct 25.

PMID:
22038346
[PubMed - indexed for MEDLINE]
18.

11,12-EET increases porto-sinusoidal resistance and may play a role in endothelial dysfunction of portal hypertension.

Sacerdoti D, Jiang H, Gaiani S, McGiff JC, Gatta A, Bolognesi M.

Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):72-5. doi: 10.1016/j.prostaglandins.2011.08.002. Epub 2011 Aug 11.

PMID:
21856435
[PubMed - indexed for MEDLINE]
19.

Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception.

Wagner K, Inceoglu B, Hammock BD.

Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):76-83. doi: 10.1016/j.prostaglandins.2011.08.001. Epub 2011 Aug 10. Review.

PMID:
21854866
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide.

Liu L, Chen C, Gong W, Li Y, Edin ML, Zeldin DC, Wang DW.

J Pharmacol Exp Ther. 2011 Nov;339(2):451-63. doi: 10.1124/jpet.111.180505. Epub 2011 Aug 16.

PMID:
21846841
[PubMed - indexed for MEDLINE]
Free PMC Article

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