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Results: 1 to 20 of 74

1.

Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers.

Tamang DL, Pirzai W, Priebe GP, Traficante DC, Pier GB, Falck JR, Morisseau C, Hammock BD, McCormick BA, Gronert K, Hurley BP.

J Immunol. 2012 Nov 15;189(10):4960-9. doi: 10.4049/jimmunol.1201922. Epub 2012 Oct 8.

PMID:
23045615
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors.

Gregus AM, Doolen S, Dumlao DS, Buczynski MW, Takasusuki T, Fitzsimmons BL, Hua XY, Taylor BK, Dennis EA, Yaksh TL.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6721-6. doi: 10.1073/pnas.1110460109. Epub 2012 Apr 9.

PMID:
22493235
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Hepoxilin A(3) protects β-cells from apoptosis in contrast to its precursor, 12-hydroperoxyeicosatetraenoic acid.

Zafiriou MP, Zelarayan LC, Noack C, Renger A, Nigam S, Siafaka-Kapadai A.

Biochim Biophys Acta. 2011 Jun;1811(6):361-9. doi: 10.1016/j.bbalip.2011.03.002. Epub 2011 Mar 17.

PMID:
21420506
[PubMed - indexed for MEDLINE]
Free Article
4.

Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase.

Cronin A, Decker M, Arand M.

J Lipid Res. 2011 Apr;52(4):712-9. doi: 10.1194/jlr.M009639. Epub 2011 Jan 7.

PMID:
21217101
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells.

Hurley BP, Pirzai W, Mumy KL, Gronert K, McCormick BA.

Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L286-94. doi: 10.1152/ajplung.00147.2010. Epub 2010 Nov 19.

PMID:
21097525
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The role of neutrophils in the event of intestinal inflammation.

Mumy KL, McCormick BA.

Curr Opin Pharmacol. 2009 Dec;9(6):697-701. doi: 10.1016/j.coph.2009.10.004. Epub 2009 Oct 24. Review.

PMID:
19854677
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3.

Pazos M, Siccardi D, Mumy KL, Bien JD, Louie S, Shi HN, Gronert K, Mrsny RJ, McCormick BA.

J Immunol. 2008 Dec 1;181(11):8044-52.

PMID:
19017997
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Distinct isoforms of phospholipase A2 mediate the ability of Salmonella enterica serotype typhimurium and Shigella flexneri to induce the transepithelial migration of neutrophils.

Mumy KL, Bien JD, Pazos MA, Gronert K, Hurley BP, McCormick BA.

Infect Immun. 2008 Aug;76(8):3614-27. doi: 10.1128/IAI.00407-08. Epub 2008 May 27.

PMID:
18505810
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Adhesion molecules involved in hepoxilin A3-mediated neutrophil transepithelial migration.

Hurley BP, Sin A, McCormick BA.

Clin Exp Immunol. 2008 Feb;151(2):297-305. Epub 2007 Nov 15.

PMID:
18005361
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Biological role of hepoxilins: upregulation of phospholipid hydroperoxide glutathione peroxidase as a cellular response to oxidative stress?

Zafiriou MP, Deva R, Ciccoli R, Siafaka-Kapadai A, Nigam S.

Prostaglandins Leukot Essent Fatty Acids. 2007 Oct-Nov;77(3-4):209-15. Epub 2007 Nov 7.

PMID:
17997296
[PubMed - indexed for MEDLINE]
11.

Bacterial-induced hepoxilin A3 secretion as a pro-inflammatory mediator.

McCormick BA.

FEBS J. 2007 Jul;274(14):3513-8. Epub 2007 Jul 2. Review.

PMID:
17608718
[PubMed - indexed for MEDLINE]
12.

Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha.

Yu Z, Schneider C, Boeglin WE, Brash AR.

Lipids. 2007 Jun;42(6):491-7. Epub 2007 Apr 14.

PMID:
17436029
[PubMed - indexed for MEDLINE]
13.

Hepoxilin analogs, potential new therapeutics in disease.

Pace-Asciak CR, Li X, Qiao N, Reynaud D, Demin P, Abdelhaleem M.

Curr Pharm Des. 2006;12(8):963-9.

PMID:
16533163
[PubMed - indexed for MEDLINE]
14.

Involvement of phospholipase A2 in Pseudomonas aeruginosa-mediated PMN transepithelial migration.

Hurley BP, Williams NL, McCormick BA.

Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L703-L709. Epub 2005 Nov 4.

PMID:
16272174
[PubMed - indexed for MEDLINE]
Free Article
15.

Hepoxilin A3 synthase.

Nigam S, Zafiriou MP.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):161-8. Epub 2005 Sep 21. Review.

PMID:
16198304
[PubMed - indexed for MEDLINE]
16.

Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A3.

Hurley BP, Siccardi D, Mrsny RJ, McCormick BA.

J Immunol. 2004 Nov 1;173(9):5712-20.

PMID:
15494523
[PubMed - indexed for MEDLINE]
Free Article
17.

Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia.

Mrsny RJ, Gewirtz AT, Siccardi D, Savidge T, Hurley BP, Madara JL, McCormick BA.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7421-6. Epub 2004 May 3.

PMID:
15123795
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Hepoxilins and trioxilins in barnacles: an analysis of their potential roles in egg hatching and larval settlement.

Vogan CL, Maskrey BH, Taylor GW, Henry S, Pace-Asciak CR, Clare AS, Rowley AF.

J Exp Biol. 2003 Sep;206(Pt 18):3219-26.

PMID:
12909703
[PubMed - indexed for MEDLINE]
Free Article
19.

Hepoxilin signaling in intact human neutrophils: biphasic elevation of intracellular calcium by unesterified hepoxilin A3.

Reynaud D, Demin PM, Sutherland M, Nigam S, Pace-Asciak CR.

FEBS Lett. 1999 Mar 12;446(2-3):236-8.

PMID:
10100848
[PubMed - indexed for MEDLINE]
Free Article
20.

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