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Results: 1 to 20 of 388

1.

Functional analysis of human thromboxane synthase polymorphic variants.

Chen CY, Poole EM, Ulrich CM, Kulmacz RJ, Wang LH.

Pharmacogenet Genomics. 2012 Sep;22(9):653-8. doi: 10.1097/FPC.0b013e3283562d82.

PMID:
22735388
[PubMed - indexed for MEDLINE]
2.

All-trans retinoic acid up-regulates Prostaglandin-E Synthase expression in human macrophages.

Mamidi S, Hofer TP, Hoffmann R, Ziegler-Heitbrock L, Frankenberger M.

Immunobiology. 2012 Jun;217(6):593-600. doi: 10.1016/j.imbio.2011.10.022. Epub 2011 Nov 3.

PMID:
22204820
[PubMed - indexed for MEDLINE]
3.

[Ligand recognition mechanism of lipocalin-type prostaglandin D synthase].

Shimamoto S, Yoshida T, Ohkubo T.

Yakugaku Zasshi. 2011;131(11):1575-81. Review. Japanese.

PMID:
22041695
[PubMed - indexed for MEDLINE]
Free Article
4.

Probing the interaction between prostacyclin synthase and prostaglandin H2 analogues or inhibitors via a combination of resonance Raman spectroscopy and molecular dynamics simulation approaches.

Chao WC, Lu JF, Wang JS, Yang HC, Chen HH, Lan YK, Yu YC, Chou PT, Wang LH.

J Am Chem Soc. 2011 Nov 23;133(46):18870-9. doi: 10.1021/ja206918w. Epub 2011 Oct 27.

PMID:
21978190
[PubMed - indexed for MEDLINE]
5.

Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2.

Yu R, Xiao L, Zhao G, Christman JW, van Breemen RB.

J Pharmacol Exp Ther. 2011 Nov;339(2):716-25. doi: 10.1124/jpet.111.185405. Epub 2011 Aug 24.

PMID:
21865441
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A facilitated approach to evaluate the inhibitor mode and potency of compounds targeting microsomal prostaglandin e synthase-1.

Spahiu L, Stenberg P, Larsson C, Wannberg J, Alterman M, Kull B, Nekhotiaeva N, Morgenstern R.

Assay Drug Dev Technol. 2011 Oct;9(5):487-95. doi: 10.1089/adt.2010.0350. Epub 2011 May 11.

PMID:
21561373
[PubMed - indexed for MEDLINE]
7.

Inhibition of untransformed prostaglandin H(2) production and stretch-induced contraction of rabbit pulmonary arteries by indoxam, a selective secretory phospholipase A(2) inhibitor.

Tanabe Y, Saito M, Morikawa Y, Kamataki A, Sawai T, Hirose M, Nakayama K.

J Pharmacol Sci. 2011;115(4):525-31. Epub 2011 Mar 16.

PMID:
21422723
[PubMed - indexed for MEDLINE]
Free Article
8.

Microsomal prostaglandin e2 synthase-1 modulates the response to vascular injury.

Wang M, Ihida-Stansbury K, Kothapalli D, Tamby MC, Yu Z, Chen L, Grant G, Cheng Y, Lawson JA, Assoian RK, Jones PL, Fitzgerald GA.

Circulation. 2011 Feb 15;123(6):631-9. doi: 10.1161/CIRCULATIONAHA.110.973685. Epub 2011 Jan 31.

PMID:
21282500
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Expression of enzymes involved in the synthesis of prostaglandin E2 in bovine in vitro-produced embryos.

Saint-Dizier M, Guyader-Joly C, Charpigny G, Grimard B, Humblot P, Ponter AA.

Zygote. 2011 Aug;19(3):277-83. doi: 10.1017/S0967199410000596. Epub 2011 Jan 14. Erratum in: Zygote. 2011 Aug;19(3):285. Charpigny, Gilles [added].

PMID:
21232167
[PubMed - indexed for MEDLINE]
10.

Prostaglandin D(2) synthesis in Oesophagostomum dentatum is mediated by cytosolic glutathione S-transferase.

Joachim A, Ruttkowski B.

Exp Parasitol. 2011 Feb;127(2):604-6. doi: 10.1016/j.exppara.2010.10.020. Epub 2010 Nov 4.

PMID:
21056037
[PubMed - indexed for MEDLINE]
11.

Time-dependent increases in ouabain-sensitive Na+, K+ -ATPase activity in aortas from diabetic rats: The role of prostanoids and protein kinase C.

Gallo LC, Davel AP, Xavier FE, Rossoni LV.

Life Sci. 2010 Aug 28;87(9-10):302-8. doi: 10.1016/j.lfs.2010.07.005. Epub 2010 Jul 15.

PMID:
20637778
[PubMed - indexed for MEDLINE]
12.

Transcellular biosynthesis of eicosanoids.

Sala A, Folco G, Murphy RC.

Pharmacol Rep. 2010 May-Jun;62(3):503-10. Review.

PMID:
20631414
[PubMed - indexed for MEDLINE]
Free Article
13.

Effects of apigenin on steroidogenesis and steroidogenic acute regulatory gene expression in mouse Leydig cells.

Li W, Pandey AK, Yin X, Chen JJ, Stocco DM, Grammas P, Wang X.

J Nutr Biochem. 2011 Mar;22(3):212-8. doi: 10.1016/j.jnutbio.2010.01.004.

PMID:
20537519
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesis.

Hamza A, Tong M, AbdulHameed MD, Liu J, Goren AC, Tai HH, Zhan CG.

J Phys Chem B. 2010 Apr 29;114(16):5605-16. doi: 10.1021/jp100668y.

PMID:
20369883
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The prostaglandin transporter PGT transports PGH(2).

Chi Y, Schuster VL.

Biochem Biophys Res Commun. 2010 Apr 30;395(2):168-72. doi: 10.1016/j.bbrc.2010.03.108. Epub 2010 Mar 25.

PMID:
20346915
[PubMed - indexed for MEDLINE]
16.

The cyclooxygenase site, but not the peroxidase site of cyclooxygenase-2 is required for neurotoxicity in hypoxic and ischemic injury.

Li W, Wu S, Ahmad M, Jiang J, Liu H, Nagayama T, Rose ME, Tyurin VA, Tyurina YY, Borisenko GG, Belikova N, Chen J, Kagan VE, Graham SH.

J Neurochem. 2010 May;113(4):965-77. doi: 10.1111/j.1471-4159.2010.06674.x. Epub 2010 Mar 17.

PMID:
20236388
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Comparison of PGH2 binding site in prostaglandin synthases.

Paragi-Vedanthi P, Doble M.

BMC Bioinformatics. 2010 Jan 18;11 Suppl 1:S51. doi: 10.1186/1471-2105-11-S1-S51.

PMID:
20122226
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Cyclo-oxygenase 2 modulates chemoresistance in breast cancer cells involving NF-kappaB.

Zatelli MC, Molè D, Tagliati F, Minoia M, Ambrosio MR, degli Uberti E.

Cell Oncol. 2009;31(6):457-65. doi: 10.3233/CLO-2009-0490.

PMID:
19940361
[PubMed - indexed for MEDLINE]
19.

Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro.

Bruno A, Di Francesco L, Coletta I, Mangano G, Alisi MA, Polenzani L, Milanese C, Anzellotti P, Ricciotti E, Dovizio M, Di Francesco A, Tacconelli S, Capone ML, Patrignani P.

Biochem Pharmacol. 2010 Apr 1;79(7):974-81. doi: 10.1016/j.bcp.2009.11.011. Epub 2009 Nov 27.

PMID:
19925781
[PubMed - indexed for MEDLINE]
20.

Green tea epigallocatechin-3-gallate inhibits microsomal prostaglandin E(2) synthase-1.

Koeberle A, Bauer J, Verhoff M, Hoffmann M, Northoff H, Werz O.

Biochem Biophys Res Commun. 2009 Oct 16;388(2):350-4. doi: 10.1016/j.bbrc.2009.08.005. Epub 2009 Aug 6.

PMID:
19665000
[PubMed - indexed for MEDLINE]

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