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J Med Chem. 2011 Mar 24;54(6):1539-54. doi: 10.1021/jm101356p. Epub 2011 Feb 23.

Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.

Author information

  • 1Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. m-ishikawa@iam.u-tokyo.ac.jp
PMID:
21344906
[PubMed - indexed for MEDLINE]
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