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Items: 1 to 20 of 592

1.

Hepatocyte nuclear factor-4α reverses malignancy of hepatocellular carcinoma through regulating miR-134 in the DLK1-DIO3 region.

Yin C, Wang PQ, Xu WP, Yang Y, Zhang Q, Ning BF, Zhang PP, Zhou WP, Xie WF, Chen WS, Zhang X.

Hepatology. 2013 Dec;58(6):1964-76. doi: 10.1002/hep.26573. Epub 2013 Oct 22.

PMID:
23775631
2.

Detection and characterization of two novel mutations in the HNF4A gene in maturity-onset diabetes of the young type 1 in two Japanese families.

Fujiwara M, Namba N, Miura K, Kitaoka T, Hirai H, Kondou H, Shimotsuji T, Numakura C, Ozono K.

Horm Res Paediatr. 2013;79(4):220-6. doi: 10.1159/000350520. Epub 2013 May 1.

PMID:
23652628
3.

Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents.

Walesky C, Edwards G, Borude P, Gunewardena S, O'Neil M, Yoo B, Apte U.

Hepatology. 2013 Jun;57(6):2480-90. doi: 10.1002/hep.26251.

4.

Genetic variations of NR2A1 in Asian populations: implications in pharmacogenetics studies.

Chew SC, Lim JS, Lee EJ, Chowbay B.

Drug Metab Pharmacokinet. 2013;28(3):278-88. Epub 2012 Dec 25.

5.

Preservation of hepatocyte nuclear factor-4α contributes to the beneficial effect of dietary medium chain triglyceride on alcohol-induced hepatic lipid dyshomeostasis in rats.

Li Q, Zhong W, Qiu Y, Kang X, Sun X, Tan X, Zhao Y, Sun X, Jia W, Zhou Z.

Alcohol Clin Exp Res. 2013 Apr;37(4):587-98. doi: 10.1111/acer.12013. Epub 2012 Nov 5.

6.

HNF4α as a marker for invasive mucinous adenocarcinoma of the lung.

Sugano M, Nagasaka T, Sasaki E, Murakami Y, Hosoda W, Hida T, Mitsudomi T, Yatabe Y.

Am J Surg Pathol. 2013 Feb;37(2):211-8. doi: 10.1097/PAS.0b013e31826be303.

PMID:
23108025
7.

Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation.

Walesky C, Gunewardena S, Terwilliger EF, Edwards G, Borude P, Apte U.

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1;304(1):G26-37. doi: 10.1152/ajpgi.00064.2012. Epub 2012 Oct 25.

8.

Association between genetic variants in the HNF4A gene and childhood-onset Crohn's disease.

Marcil V, Sinnett D, Seidman E, Boudreau F, Gendron FP, Beaulieu JF, Menard D, Lambert M, Bitton A, Sanchez R, Amre D, Levy E.

Genes Immun. 2012 Oct;13(7):556-65. doi: 10.1038/gene.2012.37. Epub 2012 Aug 23.

9.

[Zinc supplementation effects on alcoholic liver disease and the molecular mechanism].

Xiao M, Liu CB, Sun W, Dong MW, Hu GX, Li JW.

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2012 Jan;28(1):84-8. Chinese.

PMID:
22493904
10.

The transcription factor HNF-4α: a key factor of the intestinal uptake of fatty acids in mouse.

Frochot V, Alqub M, Cattin AL, Carrière V, Houllier A, Baraille F, Barbot L, Saint-Just S, Ribeiro A, Lacasa M, Cardot P, Chambaz J, Rousset M, Lacorte JM.

Am J Physiol Gastrointest Liver Physiol. 2012 Jun 1;302(11):G1253-63. doi: 10.1152/ajpgi.00329.2011. Epub 2012 Mar 29.

11.

Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors.

Fang B, Mane-Padros D, Bolotin E, Jiang T, Sladek FM.

Nucleic Acids Res. 2012 Jul;40(12):5343-56. doi: 10.1093/nar/gks190. Epub 2012 Mar 1.

12.

Inhibition of hepatitis B Virus replication by hepatocyte nuclear factor 4-alpha specific short hairpin RNA.

He F, Chen EQ, Liu L, Zhou TY, Liu C, Cheng X, Liu FJ, Tang H.

Liver Int. 2012 May;32(5):742-51. doi: 10.1111/j.1478-3231.2011.02748.x. Epub 2012 Feb 18.

PMID:
22340507
13.

Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.

Chellappa K, Jankova L, Schnabl JM, Pan S, Brelivet Y, Fung CL, Chan C, Dent OF, Clarke SJ, Robertson GR, Sladek FM.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2302-7. doi: 10.1073/pnas.1106799109. Epub 2012 Jan 30.

14.

An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis.

Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, Ogata H, Karin M, Struhl K, Hadzopoulou-Cladaras M, Iliopoulos D.

Cell. 2011 Dec 9;147(6):1233-47. doi: 10.1016/j.cell.2011.10.043. Erratum in: Cell. 2013 Feb 28;152(5):1196.

15.

Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.

Takayama K, Inamura M, Kawabata K, Katayama K, Higuchi M, Tashiro K, Nonaka A, Sakurai F, Hayakawa T, Furue MK, Mizuguchi H.

Mol Ther. 2012 Jan;20(1):127-37. doi: 10.1038/mt.2011.234. Epub 2011 Nov 8.

16.

Association of hepatocyte nuclear factor 4 alpha polymorphisms with type 2 diabetes with or without metabolic syndrome in Malaysia.

Saif-Ali R, Harun R, Kamaruddin NA, Al-Jassabi S, Ngah WZ.

Biochem Genet. 2012 Apr;50(3-4):298-308. doi: 10.1007/s10528-011-9472-2. Epub 2011 Oct 9.

PMID:
21983932
17.

Monogenic diabetes in a family with 2 unknown HNF-4A gene mutations.

Motzkau M, Meyer P, Mertens PR, Klose S.

Exp Clin Endocrinol Diabetes. 2012 Feb;120(2):89-90. doi: 10.1055/s-0031-1284378. Epub 2011 Sep 15.

PMID:
21922456
18.

HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells.

DeLaForest A, Nagaoka M, Si-Tayeb K, Noto FK, Konopka G, Battle MA, Duncan SA.

Development. 2011 Oct;138(19):4143-53. doi: 10.1242/dev.062547. Epub 2011 Aug 18.

19.

The hepatitis E virus ORF3 protein regulates the expression of liver-specific genes by modulating localization of hepatocyte nuclear factor 4.

Chandra V, Holla P, Ghosh D, Chakrabarti D, Padigaru M, Jameel S.

PLoS One. 2011;6(7):e22412. doi: 10.1371/journal.pone.0022412. Epub 2011 Jul 20.

20.

Hepatocyte nuclear factor 4A expression discriminates gastric involvement by metastatic breast carcinomas from primary gastric adenocarcinomas.

Koyama T, Sekine S, Taniguchi H, Tsuda H, Ikegami M, Hano H, Kushima R.

Hum Pathol. 2011 Nov;42(11):1777-84. doi: 10.1016/j.humpath.2011.04.002.

PMID:
21733563
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