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Items: 1 to 20 of 35

1.

Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.

Németh BC, Wartmann T, Halangk W, Sahin-Tóth M.

J Biol Chem. 2013 Aug 16;288(33):24049-62. doi: 10.1074/jbc.M113.478800. Epub 2013 Jun 27.

2.

Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation.

Batra J, Szabó A, Caulfield TR, Soares AS, Sahin-Tóth M, Radisky ES.

J Biol Chem. 2013 Apr 5;288(14):9848-59. doi: 10.1074/jbc.M113.457382. Epub 2013 Feb 19.

3.

Identification of novel missense CTRC variants in Japanese patients with chronic pancreatitis.

Masamune A, Nakano E, Kume K, Kakuta Y, Ariga H, Shimosegawa T.

Gut. 2013 Apr;62(4):653-4. doi: 10.1136/gutjnl-2012-303860. Epub 2012 Nov 7. No abstract available.

PMID:
23135764
4.

Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk.

Beer S, Zhou J, Szabó A, Keiles S, Chandak GR, Witt H, Sahin-Tóth M.

Gut. 2013 Nov;62(11):1616-24. doi: 10.1136/gutjnl-2012-303090. Epub 2012 Sep 1.

5.

Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants.

Paliwal S, Bhaskar S, Mani KR, Reddy DN, Rao GV, Singh SP, Thomas V, Chandak GR.

Gut. 2013 Nov;62(11):1602-6. doi: 10.1136/gutjnl-2012-302448. Epub 2012 May 12.

PMID:
22580415
6.

Chymotrypsin C (caldecrin) is associated with enamel development.

Lacruz RS, Smith CE, Smith SM, Hu P, Bringas P Jr, Sahin-Tóth M, Moradian-Oldak J, Paine ML.

J Dent Res. 2011 Oct;90(10):1228-33. doi: 10.1177/0022034511418231. Epub 2011 Aug 9.

7.

Chymotrypsin C mutations in chronic pancreatitis.

Zhou J, Sahin-Tóth M.

J Gastroenterol Hepatol. 2011 Aug;26(8):1238-46. doi: 10.1111/j.1440-1746.2011.06791.x. Review.

8.

Serum calcium-decreasing factor, caldecrin, ameliorates muscular dystrophy in dy/dy mice.

Tomomura M, Fujii T, Sakagami H, Tomomura A.

In Vivo. 2011 Mar-Apr;25(2):157-63.

PMID:
21471529
9.

Association of novel chymotrypsin C gene variations and haplotypes in patients with chronic pancreatitis in Chinese in Taiwan.

Chang MC, Chang YT, Wei SC, Liang PC, Jan IS, Su YN, Kuo CH, Wong JM.

Pancreatology. 2009;9(3):287-92. doi: 10.1159/000199437. Epub 2009 Apr 29.

PMID:
19407484
10.

Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis.

Masson E, Chen JM, Scotet V, Le Maréchal C, Férec C.

Hum Genet. 2008 Feb;123(1):83-91. doi: 10.1007/s00439-007-0459-3. Epub 2008 Jan 3.

PMID:
18172691
11.

Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.

Rosendahl J, Witt H, Szmola R, Bhatia E, Ozsvári B, Landt O, Schulz HU, Gress TM, Pfützer R, Löhr M, Kovacs P, Blüher M, Stumvoll M, Choudhuri G, Hegyi P, te Morsche RH, Drenth JP, Truninger K, Macek M Jr, Puhl G, Witt U, Schmidt H, Büning C, Ockenga J, Kage A, Groneberg DA, Nickel R, Berg T, Wiedenmann B, Bödeker H, Keim V, Mössner J, Teich N, Sahin-Tóth M.

Nat Genet. 2008 Jan;40(1):78-82. Epub 2007 Dec 2.

12.

Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y.

Szmola R, Sahin-Tóth M.

Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11227-32. Epub 2007 Jun 25.

13.

Molecular cloning and expression of human caldecrin.

Tomomura A, Akiyama M, Itoh H, Yoshino I, Tomomura M, Nishii Y, Noikura T, Saheki T.

FEBS Lett. 1996 May 13;386(1):26-8.

14.

Molecular cloning and expression of serum calcium-decreasing factor (caldecrin).

Tomomura A, Tomomura M, Fukushige T, Akiyama M, Kubota N, Kumaki K, Nishii Y, Noikura T, Saheki T.

J Biol Chem. 1995 Dec 22;270(51):30315-21.

15.

Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.

Szabó A, Sahin-Tóth M.

J Biol Chem. 2012 Jun 8;287(24):20701-10. doi: 10.1074/jbc.M112.360065. Epub 2012 Apr 26.

16.

Effect of chymotrypsin C and related proteins on pancreatic cancer cell migration.

Wang H, Sha W, Liu Z, Chi CW.

Acta Biochim Biophys Sin (Shanghai). 2011 May;43(5):362-71. doi: 10.1093/abbs/gmr022. Epub 2011 Apr 2.

PMID:
21460362
17.

Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants.

Derikx MH, Szmola R, te Morsche RH, Sunderasan S, Chacko A, Drenth JP.

Eur J Gastroenterol Hepatol. 2009 Aug;21(8):889-94. doi: 10.1097/MEG.0b013e32832183cf.

PMID:
19404200
18.

Evolutionally conserved intermediates between ubiquitin and NEDD8.

Kitahara R, Yamaguchi Y, Sakata E, Kasuya T, Tanaka K, Kato K, Yokoyama S, Akasaka K.

J Mol Biol. 2006 Oct 20;363(2):395-404. Epub 2006 Aug 2.

PMID:
16979187
19.

Acetaldehyde inhibits chymotrypsin and serum anti-chymotrypsin activity.

Brecher AS, Yang MP.

J Investig Med. 1998 Apr;46(4):146-52.

PMID:
9635374
20.
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