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Items: 12


Cell cycle specific distribution of killin: evidence for negative regulation of both DNA and RNA synthesis.

Qiao M, Luo D, Kuang Y, Feng H, Luo G, Liang P.

Cell Cycle. 2015;14(12):1823-9. doi: 10.1080/15384101.2015.1038686.


KLLN epigenotype-phenotype associations in Cowden syndrome.

Nizialek EA, Mester JL, Dhiman VK, Smiraglia DJ, Eng C.

Eur J Hum Genet. 2015 Nov;23(11):1538-43. doi: 10.1038/ejhg.2015.8. Epub 2015 Feb 11.


Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma.

Wang Y, Roma A, Nolley R, Abdul-Karim F, Peehl DM, Eng C.

Endocr Relat Cancer. 2014 Aug;21(4):579-86. doi: 10.1530/ERC-14-0148.


Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation.

Wang Y, Yu Q, He X, Romigh T, Altemus J, Eng C.

Mol Cancer Ther. 2014 Feb;13(2):517-27. doi: 10.1158/1535-7163.MCT-13-0655. Epub 2013 Dec 19.


Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest.

Nizialek EA, Peterson C, Mester JL, Downes-Kelly E, Eng C.

Hum Mol Genet. 2013 Jun 15;22(12):2451-61. doi: 10.1093/hmg/ddt097. Epub 2013 Feb 27.


Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas.

Wang Y, He X, Yu Q, Eng C.

Hum Mol Genet. 2013 Jun 1;22(11):2263-72. doi: 10.1093/hmg/ddt077. Epub 2013 Feb 14.


Transcription factor KLLN inhibits tumor growth by AR suppression, induces apoptosis by TP53/TP73 stimulation in prostate carcinomas, and correlates with cellular differentiation.

Wang Y, Radhakrishnan D, He X, Peehl DM, Eng C.

J Clin Endocrinol Metab. 2013 Mar;98(3):E586-94. doi: 10.1210/jc.2012-3490. Epub 2013 Feb 5.


Analysis of KLLN as a high-penetrance breast cancer predisposition gene.

Thompson ER, Gorringe KL, Choong DY, Eccles DM; kConFab, Mitchell G, Campbell IG.

Breast Cancer Res Treat. 2012 Jul;134(2):543-7. doi: 10.1007/s10549-012-2088-3. Epub 2012 May 13.


Incidence and clinical characteristics of thyroid cancer in prospective series of individuals with Cowden and Cowden-like syndrome characterized by germline PTEN, SDH, or KLLN alterations.

Ngeow J, Mester J, Rybicki LA, Ni Y, Milas M, Eng C.

J Clin Endocrinol Metab. 2011 Dec;96(12):E2063-71. doi: 10.1210/jc.2011-1616. Epub 2011 Sep 28.


Germline and somatic DNA methylation and epigenetic regulation of KILLIN in renal cell carcinoma.

Bennett KL, Campbell R, Ganapathi S, Zhou M, Rini B, Ganapathi R, Neumann HP, Eng C.

Genes Chromosomes Cancer. 2011 Aug;50(8):654-61. doi: 10.1002/gcc.20887. Epub 2011 May 16.


Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome.

Bennett KL, Mester J, Eng C.

JAMA. 2010 Dec 22;304(24):2724-31. doi: 10.1001/jama.2010.1877.


Killin is a p53-regulated nuclear inhibitor of DNA synthesis.

Cho YJ, Liang P.

Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5396-401. doi: 10.1073/pnas.0705410105. Epub 2008 Apr 2.

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