PubMed for id: 5588

Year	Number of Results
1988	1
1990	3
1991	1
1993	3
1994	2
1995	4
1996	5
1997	6
1998	6
1999	6
2000	11
2001	9
2002	12
2003	6
2004	17
2005	14
2006	5
2007	10
2008	15
2009	10
2010	25
2011	15
2012	14
2013	14
2014	6
2015	6
2016	8
2017	5
2018	2
2019	4
2020	6
2021	6
2022	4
2023	3
2024	0

1

Crocin attenuates NF-κB-mediated inflammation and proliferation in breast cancer cells by down-regulating PRKCQ.

Xu Q, Yu J, Jia G, Li Z, Xiong H. Xu Q, et al. Cytokine. 2022 Jun;154:155888. doi: 10.1016/j.cyto.2022.155888. Epub 2022 Apr 18. Cytokine. 2022. PMID: 35447530

2

The Emerging Function of PKCtheta in Cancer.

Nicolle A, Zhang Y, Belguise K. Nicolle A, et al. Biomolecules. 2021 Feb 5;11(2):221. doi: 10.3390/biom11020221. Biomolecules. 2021. PMID: 33562506 Free PMC article. Review.

3

PRKCQ rs4750316 is associated with Vogt-Koyanagi-Harada syndrome in a Han Chinese population.

Xu L, Zhao T, Yuan G, Hou S, Zeng W, Chen F. Xu L, et al. Mol Vis. 2019 Dec 2;25:834-842. eCollection 2019. Mol Vis. 2019. PMID: 31908401 Free PMC article.

4

Missense mutation in PRKCQ is associated with Crohn's disease.

Zhang YW, Xu XY, Zhang J, Yao X, Lu C, Chen CX, Yu CH, Sun J. Zhang YW, et al. J Dig Dis. 2019 May;20(5):243-247. doi: 10.1111/1751-2980.12717. Epub 2019 Apr 23. J Dig Dis. 2019. PMID: 30828974

5

Structural determinants of phorbol ester binding activity of the C1a and C1b domains of protein kinase C theta.

Czikora A, Pany S, You Y, Saini AS, Lewin NE, Mitchell GA, Abramovitz A, Kedei N, Blumberg PM, Das J. Czikora A, et al. Biochim Biophys Acta Biomembr. 2018 May;1860(5):1046-1056. doi: 10.1016/j.bbamem.2018.01.007. Epub 2018 Jan 6. Biochim Biophys Acta Biomembr. 2018. PMID: 29317197 Free PMC article.

6

PRKCQ promotes oncogenic growth and anoikis resistance of a subset of triple-negative breast cancer cells.

Byerly J, Halstead-Nussloch G, Ito K, Katsyv I, Irie HY. Byerly J, et al. Breast Cancer Res. 2016 Sep 23;18(1):95. doi: 10.1186/s13058-016-0749-6. Breast Cancer Res. 2016. PMID: 27663795 Free PMC article.

7

Discovery of selective and orally bioavailable protein kinase Cθ (PKCθ) inhibitors from a fragment hit.

George DM, Breinlinger EC, Friedman M, Zhang Y, Wang J, Argiriadi M, Bansal-Pakala P, Barth M, Duignan DB, Honore P, Lang Q, Mittelstadt S, Potin D, Rundell L, Edmunds JJ. George DM, et al. J Med Chem. 2015 Jan 8;58(1):222-36. doi: 10.1021/jm500669m. Epub 2014 Jul 7. J Med Chem. 2015. PMID: 25000588

8

Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans.

Szendroedi J, Yoshimura T, Phielix E, Koliaki C, Marcucci M, Zhang D, Jelenik T, Müller J, Herder C, Nowotny P, Shulman GI, Roden M. Szendroedi J, et al. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9597-602. doi: 10.1073/pnas.1409229111. Epub 2014 Jun 16. Proc Natl Acad Sci U S A. 2014. PMID: 24979806 Free PMC article.

9

Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells.

Zafar A, Wu F, Hardy K, Li J, Tu WJ, McCuaig R, Harris J, Khanna KK, Attema J, Gregory PA, Goodall GJ, Harrington K, Dahlstrom JE, Boulding T, Madden R, Tan A, Milburn PJ, Rao S. Zafar A, et al. Mol Cell Biol. 2014 Aug;34(16):2961-80. doi: 10.1128/MCB.01693-13. Epub 2014 Jun 2. Mol Cell Biol. 2014. PMID: 24891615 Free PMC article.

10

PKC-θ exists in an oxidized inactive form in naive human T cells.

von Essen MR, Kongsbak M, Levring TB, Hansen AK, Boding L, Lauritsen JP, Woetmann A, Baier G, Ødum N, Bonefeld CM, Geisler C. von Essen MR, et al. Eur J Immunol. 2013 Jun;43(6):1659-66. doi: 10.1002/eji.201243140. Epub 2013 Apr 12. Eur J Immunol. 2013. PMID: 23436678 Free article.

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