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38255001,37843397,37749865,37395027,37387251,37303127,37246508,37125775,37010012,36899919,36899893,36871612,36848480,36526864,36362025,36012358,35896617,35772917,35526016,35514053,35478970,35449878,35434999,35286896,34984553,34958940,34903160,34806324,34729735,34680903,34419630,34385357,34360639,34292171,34246298,34240207,34202258,34162976,34106654,34028539,33985864,33940562,33824984,33529599,33422685,33407844,33396475,33010688,32906763,32896989,32846814,32818388,32816614,32816594,32705401,32698886,32571898,32453974,32413188,32408587,32323820,32297714,32235738,32208162,32111074,32062135,32059175,32012908,31983221,31957533,31857427,31794942,31647095,31476771,31461625,31383942,31296869,31233093,31208058,31018503,31006814,30999625,30901896,30853177,30781626,30706289,30663495,30623286,30610489,30536301,30337599,30287851,30287275,30218058,30078822,29952368,29947763,29943882,29770364,29741282,29731750,29702688,29665450,29628476,29578370,29517398,29490993,29432544,29267953,29237675,29215717,29203402,29197877,29175975,29149195,29108996,28919351,28857661,28806747,28754655,28688748,28686329,28477268,28443701,28423660,28422997,28408391,27966284,27920058,27884249,27841971,27835913,27793050,27717888,27461183,27457270,27421120,27405450,27374873,27373676,27301336,27265359,27235420,27182706,27100822,26977629,26951916,26922519,26922292,26921507,26897078,26775134,26733286,26732077,26634508,26573435,26537870,26447202,26439802,26359359,26323789,26309016,26290387,26165385,26122271,26098624,26034236,26029982,25996284,25873806,25846419,25829471,25819867,25793944,25656816,25649378,25572245,25567453,25556323,25509159,25499720,25498755,25482193,25460776,25457755,25343322,25319090,25256213,25200614,25090270,25005744,24943589,24892300,24741066,24656463,24642510,24592738,24485160,24375749,24349489,24315443,24080738,24058181,24040437,24034385,24002959,24001739,23912926,23861385,23846499,23811080,23793583,23746545,23702046,23701190,23684604,23666920,23659872,23605101,23582089,23564641,23450819,23329710,23328570,23324461,23319047,23313286,23197810,23183350,23073275,23062543,23049808,22806367,22700598,22549407,22533413,22431096,22413764,22340368,22326558,22281253,22266370,22231515,22199124,22079058,22071332,22065502,22057372,22029807,21982404,21980471,21945321,21941106,21915271,21818408,21689390,21670498,21632249,21627864,21621406,21599722,21596650,21462476,21462202,21439080,21406687,21346069,21327842,21327074,21179469,21085127,20974128,20886652,20884875,20848652,20819672,20732854,20627339,20625965,20615561,20605919,20526372,20501691,20307303,20301717,20301300,20160190,20155465,20130076,20127487,20092787,20079404,20045150,20041886,19958786,19938095,19926845,19882644,19859838,19775189,19768759,19638735,19589617,19574635,19446900,19442658,19427440,19424285,19401371,19384091,19328042,19318026,19283854,19270485,19220582,19204888,19201734,19172989,19144202,19084400,18959190,18950579,18848371,18816602,18805829,18795223,18714801,18714339,18691775,18667561,18612243,18611980,18604166,18585512,18564364,18551513,18549403,18538321,18502446,18497734,18478590,18442054,18396274,18364375,18348272,18339564,18337098,18311132,18308323,18093584,18077842,18060063,18041775,18035086,18031308,17994215,17987279,17935239,17893350,17870066,17718387,17711925,17612587,17605093,17469202,17459035,17454124,17360355,17360326,17334235,17327460,17301031,17291448,17150192,17136397,17090536,16981056,16825283,16772334,16738054,16697197,16645051,16415973,16357800,16344005,16289535,16288872,16266469,16239243,16218190,16179429,16129833,16126733,16084085,16061563,15998779,15982412,15919811,15798706,15793835,15748902,15668447,15639119,15622532,15551023,15476822,15372542,15342704,15298354,15219508,15184648,15140953,15080529,15032975,15026149,14985400,14675861,14644157,14627682,13129702,12920062,12788894,12729796,12718522,12714972,12673789,12629077,12534602,12467734,12154369,12145775,12138353,12075506,12057196,12032588,12018485,12015247,11901143,11897440,11836312,11833462,11792811,11792810,11709282,11576443,11532159,11503164,11440372,11344241,11243729,11231979,10999791,10739764,10739751,10662742,9274531,9106535,9030603,8621584,8511676,8344919,7951328,3462705,3403563,2209722,1599464,37885131,37832547,37784143,37459599,37229920,36215696,36099415,36039758,35714719,34775987,33706103,33388782,33293369,33142761,32955937,32799420,32581210,32343699,32313136,32244403,32231000,31988151,31740672,31670395,31316208,31257505,31118417,31117946,30709876,30625386,30362963,30190500,30134855,30053027,29794150,29759522,29717016,29466729,29438482,29405587,29040816,28844980,28797100,28751304,28679633,28641778,28498430,28255090,28188704,27974701,27617860,27552914,27034136,26900797,26876308,26724531,26701887,26549451,25837155,25807068,25645366,25524705,25127216,24806962,24757177,24753226,24522183,24294364,24211782,24108105,24041693,23990565,23977161,23923041,23850366,23658700,23349452,23243001,22893709,22224630,21993218,21903150,21875900,21846512,21724554,21535365,21400569,21350821,21311568,20497714,2045801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Page 1

Nuclear Abnormalities in LMNA p.(Glu2Lys) Variant Segregating with LMNA-Associated Cardiocutaneous Progeria Syndrome.

Wilke MVMB, Wick M, Schwab TL, Starosta RT, Clark KJ, Connolly HM, Klee EW. Wilke MVMB, et al. Genes (Basel). 2024 Jan 18;15(1):112. doi: 10.3390/genes15010112. Genes (Basel). 2024. PMID: 38255001 Free PMC article.

Deciphering the Clinical Presentations in LMNA-related Lipodystrophy: Report of 115 Cases and a Systematic Review.

Besci O, Foss de Freitas MC, Guidorizzi NR, Guler MC, Gilio D, Maung JN, Schill RL, Hoose KS, Obua BN, Gomes AD, Yıldırım Şimşir I, Demir K, Akinci B, MacDougald OA, Oral EA. Besci O, et al. J Clin Endocrinol Metab. 2024 Feb 20;109(3):e1204-e1224. doi: 10.1210/clinem/dgad606. J Clin Endocrinol Metab. 2024. PMID: 37843397

Knockdown of LMNA inhibits Akt/β-catenin-mediated cell invasion and migration in clear cell renal cell carcinoma cells.

Xin H, Tang Y, Jin YH, Li HL, Tian Y, Yu C, Zhao ZJ, Wu MS, Pan YF. Xin H, et al. Cell Adh Migr. 2023 Dec;17(1):1-14. doi: 10.1080/19336918.2023.2260644. Epub 2023 Sep 25. Cell Adh Migr. 2023. PMID: 37749865 Free PMC article.

Differential Gene Expression Signatures and Cellular Signaling Pathways induced by Lamin A/C Transcript Variants in MCF7 Cell Line.

Batha L, Aziz MA, Zhra M, Holail J, Al-Qahtani WS, Fakhoury R, Aljada A. Batha L, et al. Front Biosci (Landmark Ed). 2023 Jun 12;28(6):113. doi: 10.31083/j.fbl2806113. Front Biosci (Landmark Ed). 2023. PMID: 37395027 Free article.

A recurrent homozygous LMNA missense variant p.Thr528Met causes atypical progeroid syndrome characterized by mandibuloacral dysostosis, severe muscular dystrophy, and skeletal deformities.

Saadi A, Navarro C, Ozalp O, Lourenco CM, Fayek R, Da Silva N, Chaouch A, Benahmed M, Kubisch C, Munnich A, Lévy N, Roll P, Pacha LA, Chaouch M, Lessel D, De Sandre-Giovannoli A. Saadi A, et al. Am J Med Genet A. 2023 Sep;191(9):2274-2289. doi: 10.1002/ajmg.a.63335. Epub 2023 Jun 30. Am J Med Genet A. 2023. PMID: 37387251

The Clinical Characteristics and Potential Molecular Mechanism of LMNA Mutation-Related Lipodystrophy.

Xiao C, Liu J, Yang C, Zhai X, Liu P, Xiao X, Yu M. Xiao C, et al. Adv Biol (Weinh). 2023 Sep;7(9):e2200301. doi: 10.1002/adbi.202200301. Epub 2023 Jun 11. Adv Biol (Weinh). 2023. PMID: 37303127

Whole-exome sequencing reveals a likely pathogenic LMNA variant causing hypertrophic cardiomyopathy.

Mahdavi M, Mohsen-Pour N, Maleki M, Ghasemi S, Tabib A, Houshmand G, Naderi N, Masoumi T, Pouraliakbar H, Kalayinia S. Mahdavi M, et al. Lab Med. 2024 Jan 6;55(1):62-70. doi: 10.1093/labmed/lmad038. Lab Med. 2024. PMID: 37246508

Modulation of cytoskeleton in cardiomyopathy caused by mutations in LMNA gene.

Chatzifrangkeskou M, Le Dour C, Muchir A. Chatzifrangkeskou M, et al. Am J Physiol Cell Physiol. 2023 Jun 1;324(6):C1223-C1235. doi: 10.1152/ajpcell.00471.2022. Epub 2023 May 1. Am J Physiol Cell Physiol. 2023. PMID: 37125775 Review.

Long-term effectiveness of ARRY-371797 in people with dilated cardiomyopathy and a faulty LMNA gene: a plain language summary.

Judge DP, Taylor MR, Li H, Oliver C, Angeli FS, Lee PA, MacRae CA. Judge DP, et al. Future Cardiol. 2023 Mar;19(3):117-126. doi: 10.2217/fca-2022-0125. Epub 2023 Apr 3. Future Cardiol. 2023. PMID: 37010012 Free article. Review.

Epigenetics in LMNA-Related Cardiomyopathy.

Wang Y, Dobreva G. Wang Y, et al. Cells. 2023 Mar 1;12(5):783. doi: 10.3390/cells12050783. Cells. 2023. PMID: 36899919 Free PMC article. Review.

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