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Items: 1 to 20 of 136

1.

Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses.

Moro K, Kabata H, Tanabe M, Koga S, Takeno N, Mochizuki M, Fukunaga K, Asano K, Betsuyaku T, Koyasu S.

Nat Immunol. 2016 Jan;17(1):76-86. doi: 10.1038/ni.3309. Epub 2015 Nov 23.

PMID:
26595888
2.

IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ.

Liu G, Xu J, Wu H, Sun D, Zhang X, Zhu X, Magez S, Shi M.

PLoS Pathog. 2015 Jul 29;11(7):e1005065. doi: 10.1371/journal.ppat.1005065. eCollection 2015 Jul.

3.

Interleukin-27 induces the endothelial differentiation in Sca-1+ cardiac resident stem cells.

Tanaka T, Obana M, Mohri T, Ebara M, Otani Y, Maeda M, Fujio Y.

Cytokine. 2015 Oct;75(2):365-72. doi: 10.1016/j.cyto.2015.06.009. Epub 2015 Jul 2.

4.

The role of IL-27 in susceptibility to post-influenza Staphylococcus aureus pneumonia.

Robinson KM, Lee B, Scheller EV, Mandalapu S, Enelow RI, Kolls JK, Alcorn JF.

Respir Res. 2015 Feb 5;16:10. doi: 10.1186/s12931-015-0168-8.

5.

Timed action of IL-27 protects from immunopathology while preserving defense in influenza.

Liu FD, Kenngott EE, Schröter MF, Kühl A, Jennrich S, Watzlawick R, Hoffmann U, Wolff T, Norley S, Scheffold A, Stumhofer JS, Saris CJ, Schwab JM, Hunter CA, Debes GF, Hamann A.

PLoS Pathog. 2014 May 8;10(5):e1004110. doi: 10.1371/journal.ppat.1004110. eCollection 2014 May.

6.

IL-27p28 is essential for parent-to-F1 acute graft-versus-host disease.

Marillier RG, Uyttenhove C, Goriely S, Marbaix E, Van Snick J.

Eur J Immunol. 2014 Jul;44(7):2064-73. doi: 10.1002/eji.201444491. Epub 2014 Apr 27.

7.

Interleukin-27 exhibited anti-inflammatory activity during Plasmodium berghei infection in mice.

Fazalul Rahiman SS, Basir R, Talib H, Tie TH, Chuah YK, Jabbarzare M, Chong WC, Mohd Yusoff MA, Nordin N, Yam MF, Abdullah WO, Abdul Majid R.

Trop Biomed. 2013 Dec;30(4):663-80.

8.

IL-27, targeting antigen-presenting cells, promotes Th17 differentiation and colitis in mice.

Visperas A, Do JS, Bulek K, Li X, Min B.

Mucosal Immunol. 2014 May;7(3):625-33. doi: 10.1038/mi.2013.82. Epub 2013 Oct 16.

9.

IL-27p28 inhibits central nervous system autoimmunity by concurrently antagonizing Th1 and Th17 responses.

Chong WP, Horai R, Mattapallil MJ, Silver PB, Chen J, Zhou R, Sergeev Y, Villasmil R, Chan CC, Caspi RR.

J Autoimmun. 2014 May;50:12-22. doi: 10.1016/j.jaut.2013.08.003. Epub 2013 Sep 7.

10.

Critical role of dendritic cell-derived IL-27 in antitumor immunity through regulating the recruitment and activation of NK and NKT cells.

Wei J, Xia S, Sun H, Zhang S, Wang J, Zhao H, Wu X, Chen X, Hao J, Zhou X, Zhu Z, Gao X, Gao JX, Wang P, Wu Z, Zhao L, Yin Z.

J Immunol. 2013 Jul 1;191(1):500-8. doi: 10.4049/jimmunol.1300328. Epub 2013 Jun 3.

11.

Interleukin 27 inhibits atherosclerosis via immunoregulation of macrophages in mice.

Hirase T, Hara H, Miyazaki Y, Ide N, Nishimoto-Hazuku A, Fujimoto H, Saris CJ, Yoshida H, Node K.

Am J Physiol Heart Circ Physiol. 2013 Aug 1;305(3):H420-9. doi: 10.1152/ajpheart.00198.2013. Epub 2013 May 31.

12.

Antitumor effects obtained by autologous Lewis lung cancer cell vaccine engineered to secrete mouse interleukin 27 by means of cationic liposome.

Zhang J, Tian H, Li C, Cheng L, Zhang S, Zhang X, Wang R, Xu F, Dai L, Shi G, Chen X, Li Y, Du T, Deng J, Liu Y, Yang Y, Wei Y, Deng H.

Mol Immunol. 2013 Oct;55(3-4):264-74. doi: 10.1016/j.molimm.2013.02.006. Epub 2013 Mar 21.

PMID:
23522926
13.

A polyglutamic acid motif confers IL-27 hydroxyapatite and bone-binding properties.

Tormo AJ, Beaupré LA, Elson G, Crabé S, Gauchat JF.

J Immunol. 2013 Mar 15;190(6):2931-7. doi: 10.4049/jimmunol.1201460. Epub 2013 Feb 6.

14.

IL-27 activates Th1-mediated responses in imiquimod-induced psoriasis-like skin lesions.

Shibata S, Tada Y, Asano Y, Yanaba K, Sugaya M, Kadono T, Kanda N, Watanabe S, Sato S.

J Invest Dermatol. 2013 Feb;133(2):479-88. doi: 10.1038/jid.2012.313. Epub 2012 Sep 6.

15.

IL-27 promotes T cell-dependent colitis through multiple mechanisms.

Cox JH, Kljavin NM, Ramamoorthi N, Diehl L, Batten M, Ghilardi N.

J Exp Med. 2011 Jan 17;208(1):115-23. doi: 10.1084/jem.20100410. Epub 2010 Dec 20.

16.

The secreted form of p28 subunit of interleukin (IL)-27 inhibits biological functions of IL-27 and suppresses anti-allogeneic immune responses.

Shimozato O, Sato A, Kawamura K, Chiyo M, Ma G, Li Q, Tagawa M.

Immunology. 2009 Sep;128(1 Suppl):e816-25. doi: 10.1111/j.1365-2567.2009.03088.x. Epub 2009 Mar 23.

17.

Distinct response of liver myeloid dendritic cells to endotoxin is mediated by IL-27.

Chen Y, Jiang G, Yang HR, Gu X, Wang L, Hsieh CC, Chou HS, Fung JJ, Qian S, Lu L.

J Hepatol. 2009 Sep;51(3):510-9. doi: 10.1016/j.jhep.2009.04.026. Epub 2009 Jun 13.

18.

The pathogenic role of interleukin-27 in autoimmune diabetes.

Wang R, Han G, Wang J, Chen G, Xu R, Wang L, Li X, Shen B, Li Y.

Cell Mol Life Sci. 2008 Nov;65(23):3851-60. doi: 10.1007/s00018-008-8540-1.

PMID:
18931971
19.

Production of IL-12, IL-23 and IL-27p28 by bone marrow-derived conventional dendritic cells rather than macrophages after LPS/TLR4-dependent induction by Salmonella Enteritidis.

Siegemund S, Schütze N, Freudenberg MA, Lutz MB, Straubinger RK, Alber G.

Immunobiology. 2007;212(9-10):739-50. Epub 2007 Nov 9.

PMID:
18086375
20.

IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.

Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi K.

J Immunol. 2007 Oct 1;179(7):4415-23. Erratum in: J Immunol. 2010 Mar 15;184(6):3298.

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