PubMed for id: 22068

Year	Number of Results
1996	1
1997	1
1998	2
1999	2
2000	3
2001	1
2002	2
2003	1
2004	4
2005	5
2006	4
2007	4
2008	9
2009	13
2010	11
2011	20
2012	17
2013	16
2014	21
2015	15
2016	13
2017	12
2018	8
2019	11
2020	13
2021	10
2022	19
2023	6
2024	4

1

The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment.

Abcouwer SF, Miglioranza Scavuzzi B, Kish PE, Kong D, Shanmugam S, Le XA, Yao J, Hager H, Zacks DN. Abcouwer SF, et al. J Neuroinflammation. 2024 Mar 25;21(1):74. doi: 10.1186/s12974-024-03062-2. J Neuroinflammation. 2024. PMID: 38528525 Free PMC article.

2

Trpc6 knockout protects against renal fibrosis by restraining the CN‑NFAT2 signaling pathway in T2DM mice.

Sun R, Han M, Liu Y, Su Y, Shi Q, Huang L, Kong L, Li W, Li W. Sun R, et al. Mol Med Rep. 2024 Jan;29(1):13. doi: 10.3892/mmr.2023.13136. Epub 2023 Dec 1. Mol Med Rep. 2024. PMID: 38038121 Free PMC article.

3

Trpc6 knockout improves behavioral dysfunction and reduces Aβ production by inhibiting CN-NFAT1 signaling in T2DM mice.

Kong L, Sun R, Zhou H, Shi Q, Liu Y, Han M, Li W, Qun S, Li W. Kong L, et al. Exp Neurol. 2023 May;363:114350. doi: 10.1016/j.expneurol.2023.114350. Epub 2023 Feb 13. Exp Neurol. 2023. PMID: 36791875

4

New Positive TRPC6 Modulator Penetrates Blood-Brain Barrier, Eliminates Synaptic Deficiency and Restores Memory Deficit in 5xFAD Mice.

Zernov N, Veselovsky AV, Poroikov VV, Melentieva D, Bolshakova A, Popugaeva E. Zernov N, et al. Int J Mol Sci. 2022 Nov 4;23(21):13552. doi: 10.3390/ijms232113552. Int J Mol Sci. 2022. PMID: 36362339 Free PMC article.

5

Gain-of-function, focal segmental glomerulosclerosis Trpc6 mutation minimally affects susceptibility to renal injury in several mouse models.

Brown BJ, Boekell KL, Stotter BR, Talbot BE, Schlondorff JS. Brown BJ, et al. PLoS One. 2022 Aug 1;17(8):e0272313. doi: 10.1371/journal.pone.0272313. eCollection 2022. PLoS One. 2022. PMID: 35913909 Free PMC article.

6

Trpc6 gain-of-function disease mutation enhances phosphatidylserine exposure in murine platelets.

Boekell KL, Brown BJ, Talbot BE, Schlondorff JS. Boekell KL, et al. PLoS One. 2022 Jun 24;17(6):e0270431. doi: 10.1371/journal.pone.0270431. eCollection 2022. PLoS One. 2022. PMID: 35749414 Free PMC article.

7

Transient receptor potential cation channel 6 deficiency leads to increased body weight and metabolic dysfunction.

Wang Z, do Carmo JM, da Silva AA, Fu Y, Jaynes LT, Sears J, Li X, J Mouton A, Omoto ACM, Xu BP, Hall JE. Wang Z, et al. Am J Physiol Regul Integr Comp Physiol. 2022 Jul 1;323(1):R81-R97. doi: 10.1152/ajpregu.00097.2021. Epub 2022 May 10. Am J Physiol Regul Integr Comp Physiol. 2022. PMID: 35537100 Free PMC article.

8

Stimulation of the EP₃ receptor causes lung oedema by activation of TRPC6 in pulmonary endothelial cells.

Jiang T, Samapati R, Klassen S, Lei D, Erfinanda L, Jankowski V, Simmons S, Yin J, Arenz C, Dietrich A, Gudermann T, Adam D, Schaefer M, Jankowski J, Flockerzi V, Nüsing R, Uhlig S, Kuebler WM. Jiang T, et al. Eur Respir J. 2022 Oct 13;60(4):2102635. doi: 10.1183/13993003.02635-2021. Print 2022 Oct. Eur Respir J. 2022. PMID: 35450969 Free article.

9

Role of TRPC6 in kidney damage after acute ischemic kidney injury.

Zheng Z, Tsvetkov D, Bartolomaeus TUP, Erdogan C, Krügel U, Schleifenbaum J, Schaefer M, Nürnberg B, Chai X, Ludwig FA, N'diaye G, Köhler MB, Wu K, Gollasch M, Markó L. Zheng Z, et al. Sci Rep. 2022 Feb 22;12(1):3038. doi: 10.1038/s41598-022-06703-9. Sci Rep. 2022. PMID: 35194063 Free PMC article.

10

Cortex Mori Radicis Attenuates Streptozotocin-induced Diabetic Renal Injury in Mice via Regulation of Transient Receptor Potential Canonical Channel 6.

Zhai Y, Li D, Wang Z, Shao L, Yin N, Li W. Zhai Y, et al. Endocr Metab Immune Disord Drug Targets. 2022;22(8):862-873. doi: 10.2174/1871530322666220110161458. Endocr Metab Immune Disord Drug Targets. 2022. PMID: 35016601

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