PubMed for id: 2139

Year	Number of Results
1996	1
1997	4
1999	2
2000	1
2001	1
2002	3
2003	1
2004	2
2005	2
2007	1
2008	1
2009	6
2010	5
2011	3
2012	5
2013	5
2014	4
2015	2
2016	3
2017	7
2018	1
2019	1
2020	3
2021	4
2022	2
2023	1
2024	0

1

Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.

Anantharajan J, Baburajendran N, Lin G, Loh YY, Xu W, Ahmad NHB, Liu S, Jansson AE, Kuan JWL, Ng EY, Yeo YK, Hung AW, Joy J, Hill J, Ford HL, Zhao R, Keller TH, Kang C. Anantharajan J, et al. Protein Sci. 2022 Feb;31(2):422-431. doi: 10.1002/pro.4234. Epub 2021 Nov 18. Protein Sci. 2022. PMID: 34761455 Free PMC article.

2

Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe.

Zhang G, Dong Z, Gimple RC, Wolin A, Wu Q, Qiu Z, Wood LM, Shen JZ, Jiang L, Zhao L, Lv D, Prager BC, Kim LJY, Wang X, Zhang L, Anderson RL, Moore JK, Bao S, Keller TH, Lin G, Kang C, Hamerlik P, Zhao R, Ford HL, Rich JN. Zhang G, et al. J Exp Med. 2021 Nov 1;218(11):e20202669. doi: 10.1084/jem.20202669. Epub 2021 Oct 7. J Exp Med. 2021. PMID: 34617969 Free PMC article.

3

EYA2 suppresses the progression of hepatocellular carcinoma via SOCS3-mediated blockade of JAK/STAT signaling.

Liu ZK, Li C, Zhang RY, Wei D, Shang YK, Yong YL, Kong LM, Zheng NS, Liu K, Lu M, Liu M, Hu CX, Yang XZ, Chen ZN, Bian H. Liu ZK, et al. Mol Cancer. 2021 May 27;20(1):79. doi: 10.1186/s12943-021-01377-9. Mol Cancer. 2021. PMID: 34044846 Free PMC article.

4

Eya2 overexpression promotes the invasion of human astrocytoma through the regulation of ERK/MMP9 signaling.

Wen Z, Liang C, Pan Q, Wang Y. Wen Z, et al. Int J Mol Med. 2017 Nov;40(5):1315-1322. doi: 10.3892/ijmm.2017.3132. Epub 2017 Sep 13. Int J Mol Med. 2017. PMID: 28901379 Free PMC article.

5

Aberrant hypomethylation and overexpression of the eyes absent homologue 2 suppresses tumor cell growth of human lung adenocarcinoma cells.

Gao T, Zheng S, Li Q, Ran P, Sun L, Yuan Y, Xiao C. Gao T, et al. Oncol Rep. 2015 Nov;34(5):2333-42. doi: 10.3892/or.2015.4245. Epub 2015 Sep 2. Oncol Rep. 2015. PMID: 26329363

6

Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth.

Vincent A, Hong SM, Hu C, Omura N, Young A, Kim H, Yu J, Knight S, Ayars M, Griffith M, Van Seuningen I, Maitra A, Goggins M. Vincent A, et al. Oncotarget. 2014 May 15;5(9):2575-87. doi: 10.18632/oncotarget.1842. Oncotarget. 2014. PMID: 24810906 Free PMC article.

7

Human HAD phosphatases: structure, mechanism, and roles in health and disease.

Seifried A, Schultz J, Gohla A. Seifried A, et al. FEBS J. 2013 Jan;280(2):549-71. doi: 10.1111/j.1742-4658.2012.08633.x. Epub 2012 Jun 13. FEBS J. 2013. PMID: 22607316 Free article. Review.

8

[Expression of EYA2 in non-small cell lang cancer].

Guo JT, Ding LH, Liang CY, Zhou NK, Ye QN. Guo JT, et al. Zhonghua Zhong Liu Za Zhi. 2009 Jul;31(7):528-31. Zhonghua Zhong Liu Za Zhi. 2009. PMID: 19950702 Chinese.

9

Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor.

Jung SK, Jeong DG, Chung SJ, Kim JH, Park BC, Tonks NK, Ryu SE, Kim SJ. Jung SK, et al. FASEB J. 2010 Feb;24(2):560-9. doi: 10.1096/fj.09-143891. Epub 2009 Oct 26. FASEB J. 2010. PMID: 19858093 Free PMC article.

10

Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth.

Zhang L, Yang N, Huang J, Buckanovich RJ, Liang S, Barchetti A, Vezzani C, O'Brien-Jenkins A, Wang J, Ward MR, Courreges MC, Fracchioli S, Medina A, Katsaros D, Weber BL, Coukos G. Zhang L, et al. Cancer Res. 2005 Feb 1;65(3):925-32. Cancer Res. 2005. PMID: 15705892

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