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Items: 1 to 20 of 689

1.

Effects of macrophage-dependent peroxisome proliferator-activated receptor γ signalling on adhesion formation after abdominal surgery in an experimental model.

Hong GS, Schwandt T, Stein K, Schneiker B, Kummer MP, Heneka MT, Kitamura K, Kalff JC, Wehner S.

Br J Surg. 2015 Nov;102(12):1506-16. doi: 10.1002/bjs.9907. Epub 2015 Aug 27.

PMID:
26313905
2.

Structurally-diverse, PPARγ-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells.

Watt J, Schlezinger JJ.

Toxicology. 2015 May 4;331:66-77. doi: 10.1016/j.tox.2015.03.006. Epub 2015 Mar 14.

PMID:
25777084
3.

Activation of peroxisome proliferator-activated receptor α induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders.

Ghosh A, Jana M, Modi K, Gonzalez FJ, Sims KB, Berry-Kravis E, Pahan K.

J Biol Chem. 2015 Apr 17;290(16):10309-24. doi: 10.1074/jbc.M114.610659. Epub 2015 Mar 6.

PMID:
25750174
4.

PPARα regulates endothelial progenitor cell maturation and myeloid lineage differentiation through a NADPH oxidase-dependent mechanism in mice.

Vergori L, Lauret E, Gaceb A, Beauvillain C, Andriantsitohaina R, Martinez MC.

Stem Cells. 2015 Apr;33(4):1292-303. doi: 10.1002/stem.1924.

PMID:
25524540
5.

Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology.

Szalowska E, Tesfay HA, van Hijum SA, Kersten S.

BMC Genomics. 2014 Dec 15;15:1106. doi: 10.1186/1471-2164-15-1106.

6.

Astragalus polysaccharides repress myocardial lipotoxicity in a PPARalpha-dependent manner in vitro and in vivo in mice.

Chen W, Lai Y, Wang L, Xia Y, Chen W, Zhao X, Yu M, Li Y, Zhang Y, Ye H.

J Diabetes Complications. 2015 Mar;29(2):164-75. doi: 10.1016/j.jdiacomp.2014.11.007. Epub 2014 Nov 25.

PMID:
25499591
7.

Icariin is a PPARα activator inducing lipid metabolic gene expression in mice.

Lu YF, Xu YY, Jin F, Wu Q, Shi JS, Liu J.

Molecules. 2014 Nov 6;19(11):18179-91. doi: 10.3390/molecules191118179.

8.

Peroxisome proliferator-activated receptor α protects capillary pericytes in the retina.

Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins AJ, Keech AC, Humphries KM, Gu X, Elliott MH, Xia X, Ma JX.

Am J Pathol. 2014 Oct;184(10):2709-20. doi: 10.1016/j.ajpath.2014.06.021. Epub 2014 Aug 7.

9.

PPARα-dependent exacerbation of experimental colitis by the hypolipidemic drug fenofibrate.

Qi Y, Jiang C, Tanaka N, Krausz KW, Brocker CN, Fang ZZ, Bredell BX, Shah YM, Gonzalez FJ.

Am J Physiol Gastrointest Liver Physiol. 2014 Sep 1;307(5):G564-73. doi: 10.1152/ajpgi.00153.2014. Epub 2014 Jul 17.

10.

The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice.

Pawlak M, Baugé E, Bourguet W, De Bosscher K, Lalloyer F, Tailleux A, Lebherz C, Lefebvre P, Staels B.

Hepatology. 2014 Nov;60(5):1593-606. doi: 10.1002/hep.27297. Epub 2014 Oct 1.

PMID:
24995693
11.

PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis.

Liu M, Montgomery MK, Fiveash CE, Osborne B, Cooney GJ, Bell-Anderson K, Turner N.

Sci Rep. 2014 Jul 2;4:5538. doi: 10.1038/srep05538.

12.

Peroxisome proliferator-activated receptor α activation induces hepatic steatosis, suggesting an adverse effect.

Yan F, Wang Q, Xu C, Cao M, Zhou X, Wang T, Yu C, Jing F, Chen W, Gao L, Zhao J.

PLoS One. 2014 Jun 13;9(6):e99245. doi: 10.1371/journal.pone.0099245. eCollection 2014.

13.

Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice.

Cotter DG, Ercal B, d'Avignon DA, Dietzen DJ, Crawford PA.

Am J Physiol Endocrinol Metab. 2014 Jul 15;307(2):E176-85. doi: 10.1152/ajpendo.00087.2014. Epub 2014 May 27.

14.

β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.

Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE.

Cell Metab. 2014 Jan 7;19(1):96-108. doi: 10.1016/j.cmet.2013.12.003.

15.

Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner.

Bolsoni-Lopes A, Festuccia WT, Farias TS, Chimin P, Torres-Leal FL, Derogis PB, de Andrade PB, Miyamoto S, Lima FB, Curi R, Alonso-Vale MI.

Am J Physiol Endocrinol Metab. 2013 Nov 1;305(9):E1093-102. doi: 10.1152/ajpendo.00082.2013. Epub 2013 Sep 10.

16.

Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α.

Roy A, Jana M, Corbett GT, Ramaswamy S, Kordower JH, Gonzalez FJ, Pahan K.

Cell Rep. 2013 Aug 29;4(4):724-37. doi: 10.1016/j.celrep.2013.07.028. Epub 2013 Aug 22.

17.

A meta-analysis study of gene expression datasets in mouse liver under PPARα knockout.

He K, Wang Z, Wang Q, Pan Y.

Genet Res (Camb). 2013 Jun;95(2-3):78-88. doi: 10.1017/S0016672313000098.

PMID:
23938112
18.

Proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.

Li S, Mariappan N, Megyesi J, Shank B, Kannan K, Theus S, Price PM, Duffield JS, Portilla D.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F618-27. doi: 10.1152/ajprenal.00309.2013. Epub 2013 Jun 26.

19.

Activation of PPARα by Wy-14643 ameliorates systemic lipopolysaccharide-induced acute lung injury.

Yoo SH, Abdelmegeed MA, Song BJ.

Biochem Biophys Res Commun. 2013 Jul 5;436(3):366-71. doi: 10.1016/j.bbrc.2013.05.073. Epub 2013 May 29.

20.

Tempol prevents cardiac oxidative damage and left ventricular dysfunction in the PPAR-α KO mouse.

Guellich A, Damy T, Conti M, Claes V, Samuel JL, Pineau T, Lecarpentier Y, Coirault C.

Am J Physiol Heart Circ Physiol. 2013 Jun 1;304(11):H1505-12. doi: 10.1152/ajpheart.00669.2012. Epub 2013 Mar 29.

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