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Results: 7

1.

A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution.

Auld DS, Zhang YQ, Southall NT, Rai G, Landsman M, MacLure J, Langevin D, Thomas CJ, Austin CP, Inglese J.

J Med Chem. 2009 Mar 12;52(5):1450-8. doi: 10.1021/jm8014525.

PMID:
19215089
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Characterization of chemical libraries for luciferase inhibitory activity.

Auld DS, Southall NT, Jadhav A, Johnson RL, Diller DJ, Simeonov A, Austin CP, Inglese J.

J Med Chem. 2008 Apr 24;51(8):2372-86. doi: 10.1021/jm701302v. Epub 2008 Mar 26.

PMID:
18363348
[PubMed - indexed for MEDLINE]
3.

Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II).

Schröter T, Minond D, Weiser A, Dao C, Habel J, Spicer T, Chase P, Baillargeon P, Scampavia L, Schürer S, Chung C, Mader C, Southern M, Tsinoremas N, LoGrasso P, Hodder P.

J Biomol Screen. 2008 Jan;13(1):17-28. doi: 10.1177/1087057107310806.

PMID:
18227223
[PubMed - indexed for MEDLINE]
4.

Bioluminescent assays for high-throughput screening.

Fan F, Wood KV.

Assay Drug Dev Technol. 2007 Feb;5(1):127-36. Review.

PMID:
17355205
[PubMed - indexed for MEDLINE]
5.

Identification of kinase inhibitors by an ATP depletion method.

Singh P, Harden BJ, Lillywhite BJ, Broad PM.

Assay Drug Dev Technol. 2004 Apr;2(2):161-9.

PMID:
15165512
[PubMed - indexed for MEDLINE]
6.

Manipulation of alternative splicing by a newly developed inhibitor of Clks.

Muraki M, Ohkawara B, Hosoya T, Onogi H, Koizumi J, Koizumi T, Sumi K, Yomoda J, Murray MV, Kimura H, Furuichi K, Shibuya H, Krainer AR, Suzuki M, Hagiwara M.

J Biol Chem. 2004 Jun 4;279(23):24246-54. Epub 2004 Mar 8.

PMID:
15010457
[PubMed - indexed for MEDLINE]
Free Article
7.

Determining appropriate substrate conversion for enzymatic assays in high-throughput screening.

Wu G, Yuan Y, Hodge CN.

J Biomol Screen. 2003 Dec;8(6):694-700.

PMID:
14711395
[PubMed - indexed for MEDLINE]

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