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Items: 11

1.

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics.

Scott FJ, Khalaf AI, Giordani F, Wong PE, Duffy S, Barrett M, Avery VM, Suckling CJ.

Eur J Med Chem. 2016 Jun 30;116:116-25. doi: 10.1016/j.ejmech.2016.03.064. Epub 2016 Mar 29.

2.

Identification and Characterization of FTY720 for the Treatment of Human African Trypanosomiasis.

Jones AJ, Kaiser M, Avery VM.

Antimicrob Agents Chemother. 2015 Dec 14;60(3):1859-61. doi: 10.1128/AAC.02116-15.

3.

Future treatment options for human African trypanosomiasis.

Jones AJ, Avery VM.

Expert Rev Anti Infect Ther. 2015;13(12):1429-32. doi: 10.1586/14787210.2015.1094374. Epub 2015 Sep 28.

PMID:
26414688
4.

6-Arylpyrazine-2-carboxamides: A New Core for Trypanosoma brucei Inhibitors.

Rahmani R, Ban K, Jones AJ, Ferrins L, Ganame D, Sykes ML, Avery VM, White KL, Ryan E, Kaiser M, Charman SA, Baell JB.

J Med Chem. 2015 Sep 10;58(17):6753-65. doi: 10.1021/acs.jmedchem.5b00438. Epub 2015 Aug 30.

PMID:
26247439
5.

Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites.

Engel JA, Jones AJ, Avery VM, Sumanadasa SD, Ng SS, Fairlie DP, Adams TS, Andrews KT.

Int J Parasitol Drugs Drug Resist. 2015 Jun 20;5(3):117-26. doi: 10.1016/j.ijpddr.2015.05.004. eCollection 2015 Dec.

6.

Trypanocidal activity of marine natural products.

Jones AJ, Grkovic T, Sykes ML, Avery VM.

Mar Drugs. 2013 Oct 22;11(10):4058-82. doi: 10.3390/md11104058. Review.

7.

3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.

Ferrins L, Rahmani R, Sykes ML, Jones AJ, Avery VM, Teston E, Almohaywi B, Yin J, Smith J, Hyland C, White KL, Ryan E, Campbell M, Charman SA, Kaiser M, Baell JB.

Eur J Med Chem. 2013 Aug;66:450-65. doi: 10.1016/j.ejmech.2013.05.007. Epub 2013 May 16.

PMID:
23831695
8.

Whole-organism high-throughput screening against Trypanosoma brucei brucei.

Jones AJ, Avery VM.

Expert Opin Drug Discov. 2013 May;8(5):495-507. doi: 10.1517/17460441.2013.783816. Epub 2013 Mar 31. Review.

PMID:
23540598
9.

Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign.

Sykes ML, Baell JB, Kaiser M, Chatelain E, Moawad SR, Ganame D, Ioset JR, Avery VM.

PLoS Negl Trop Dis. 2012;6(11):e1896. doi: 10.1371/journal.pntd.0001896. Epub 2012 Nov 29.

11.
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