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Results: 1 to 20 of 46

1.

Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemia.

Chen J, Petrus M, Bryant BR, Nguyen VP, Goldman CK, Bamford R, Morris JC, Janik JE, Waldmann TA.

Blood. 2010 Dec 23;116(26):5948-56. doi: 10.1182/blood-2010-04-277418. Epub 2010 Sep 21.

PMID:
20858854
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550).

Jiang JK, Ghoreschi K, Deflorian F, Chen Z, Perreira M, Pesu M, Smith J, Nguyen DT, Liu EH, Leister W, Costanzi S, O'Shea JJ, Thomas CJ.

J Med Chem. 2008 Dec 25;51(24):8012-8. doi: 10.1021/jm801142b.

PMID:
19053756
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Tracking antigen-driven responses by flow cytometry: monitoring proliferation by dye dilution.

Wallace PK, Tario JD Jr, Fisher JL, Wallace SS, Ernstoff MS, Muirhead KA.

Cytometry A. 2008 Nov;73(11):1019-34. doi: 10.1002/cyto.a.20619.

PMID:
18785636
[PubMed - indexed for MEDLINE]
Free Article
4.

Flow cytometric analysis of cell division by dye dilution.

Lyons AB, Doherty KV.

Curr Protoc Cytom. 2004 Feb;Chapter 9:Unit 9.11. doi: 10.1002/0471142956.cy0911s27.

PMID:
18770808
[PubMed - indexed for MEDLINE]
5.

Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism.

Chen J, Petrus M, Bryant BR, Phuc Nguyen V, Stamer M, Goldman CK, Bamford R, Morris JC, Janik JE, Waldmann TA.

Blood. 2008 May 15;111(10):5163-72. doi: 10.1182/blood-2007-09-113654. Epub 2008 Mar 13.

PMID:
18339896
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Anti-Tac (daclizumab, Zenapax) in the treatment of leukemia, autoimmune diseases, and in the prevention of allograft rejection: a 25-year personal odyssey.

Waldmann TA.

J Clin Immunol. 2007 Jan;27(1):1-18. Epub 2007 Jan 11. Review.

PMID:
17216565
[PubMed - indexed for MEDLINE]
7.

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design.

Waldmann TA.

Nat Rev Immunol. 2006 Aug;6(8):595-601. Review.

PMID:
16868550
[PubMed - indexed for MEDLINE]
8.

Combined use of the JAK3 inhibitor CP-690,550 with mycophenolate mofetil to prevent kidney allograft rejection in nonhuman primates.

Borie DC, Larson MJ, Flores MG, Campbell A, Rousvoal G, Zhang S, Higgins JP, Ball DJ, Kudlacz EM, Brissette WH, Elliott EA, Reitz BA, Changelian PS.

Transplantation. 2005 Dec 27;80(12):1756-64.

PMID:
16378072
[PubMed - indexed for MEDLINE]
9.

Effects of JAK3 inhibition with CP-690,550 on immune cell populations and their functions in nonhuman primate recipients of kidney allografts.

Paniagua R, Si MS, Flores MG, Rousvoal G, Zhang S, Aalami O, Campbell A, Changelian PS, Reitz BA, Borie DC.

Transplantation. 2005 Nov 15;80(9):1283-92.

PMID:
16314797
[PubMed - indexed for MEDLINE]
10.

Molecular mechanisms of cellular transformation by HTLV-1 Tax.

Grassmann R, Aboud M, Jeang KT.

Oncogene. 2005 Sep 5;24(39):5976-85. Review.

PMID:
16155604
[PubMed - indexed for MEDLINE]
11.

Immunosuppression by the JAK3 inhibitor CP-690,550 delays rejection and significantly prolongs kidney allograft survival in nonhuman primates.

Borie DC, Changelian PS, Larson MJ, Si MS, Paniagua R, Higgins JP, Holm B, Campbell A, Lau M, Zhang S, Flores MG, Rousvoal G, Hawkins J, Ball DA, Kudlacz EM, Brissette WH, Elliott EA, Reitz BA, Morris RE.

Transplantation. 2005 Apr 15;79(7):791-801.

PMID:
15818321
[PubMed - indexed for MEDLINE]
12.

Allogeneic hematopoietic stem cell transplantation provides sustained long-term survival for patients with adult T-cell leukemia/lymphoma.

Fukushima T, Miyazaki Y, Honda S, Kawano F, Moriuchi Y, Masuda M, Tanosaki R, Utsunomiya A, Uike N, Yoshida S, Okamura J, Tomonaga M.

Leukemia. 2005 May;19(5):829-34.

PMID:
15744352
[PubMed - indexed for MEDLINE]
13.

The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+ cell numbers in cynomolgus monkey blood following chronic oral dosing.

Conklyn M, Andresen C, Changelian P, Kudlacz E.

J Leukoc Biol. 2004 Dec;76(6):1248-55. Epub 2004 Sep 15.

PMID:
15371489
[PubMed - indexed for MEDLINE]
Free Article
14.

Clinical trials for malignant lymphoma in Japan.

Tobinai K, Hotta T.

Jpn J Clin Oncol. 2004 Jul;34(7):369-78. Review.

PMID:
15342663
[PubMed - indexed for MEDLINE]
Free Article
15.

Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation.

Jeang KT, Giam CZ, Majone F, Aboud M.

J Biol Chem. 2004 Jul 30;279(31):31991-4. Epub 2004 Apr 16. Review. No abstract available.

PMID:
15090550
[PubMed - indexed for MEDLINE]
Free Article
16.

Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor.

Changelian PS, Flanagan ME, Ball DJ, Kent CR, Magnuson KS, Martin WH, Rizzuti BJ, Sawyer PS, Perry BD, Brissette WH, McCurdy SP, Kudlacz EM, Conklyn MJ, Elliott EA, Koslov ER, Fisher MB, Strelevitz TJ, Yoon K, Whipple DA, Sun J, Munchhof MJ, Doty JL, Casavant JM, Blumenkopf TA, Hines M, Brown MF, Lillie BM, Subramanyam C, Shang-Poa C, Milici AJ, Beckius GE, Moyer JD, Su C, Woodworth TG, Gaweco AS, Beals CR, Littman BH, Fisher DA, Smith JF, Zagouras P, Magna HA, Saltarelli MJ, Johnson KS, Nelms LF, Des Etages SG, Hayes LS, Kawabata TT, Finco-Kent D, Baker DL, Larson M, Si MS, Paniagua R, Higgins J, Holm B, Reitz B, Zhou YJ, Morris RE, O'Shea JJ, Borie DC.

Science. 2003 Oct 31;302(5646):875-8.

PMID:
14593182
[PubMed - indexed for MEDLINE]
Free Article
17.

IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients.

Azimi N, Nagai M, Jacobson S, Waldmann TA.

Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14559-64. Epub 2001 Nov 20.

PMID:
11717409
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells.

Fehniger TA, Suzuki K, Ponnappan A, VanDeusen JB, Cooper MA, Florea SM, Freud AG, Robinson ML, Durbin J, Caligiuri MA.

J Exp Med. 2001 Jan 15;193(2):219-31.

PMID:
11208862
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

IL-2Ralpha-Directed monoclonal antibodies provide effective therapy in a murine model of adult T-cell leukemia by a mechanism other than blockade of IL-2/IL-2Ralpha interaction.

Phillips KE, Herring B, Wilson LA, Rickford MS, Zhang M, Goldman CK, Tso JY, Waldmann TA.

Cancer Res. 2000 Dec 15;60(24):6977-84.

PMID:
11156399
[PubMed - indexed for MEDLINE]
Free Article
20.

Advances in interleukin 2 receptor targeted treatment.

Morris JC, Waldmann TA.

Ann Rheum Dis. 2000 Nov;59 Suppl 1:i109-14. Review.

PMID:
11053100
[PubMed - indexed for MEDLINE]
Free PMC Article
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