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Results: 1 to 20 of 101

1.

An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells.

Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, Moustafa Z, Thomas RK, Greulich H, Schinzel A, Zaghlul S, Batt D, Ettenberg S, Meyerson M, Schoeberl B, Kung AL, Hahn WC, Drapkin R, Livingston DM, Liu JF.

Cancer Cell. 2010 Mar 16;17(3):298-310. doi: 10.1016/j.ccr.2009.12.047. Erratum in: Cancer Cell. 2010 Apr 13;17(4):412.

PMID:
20227043
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Neuregulin/erythroblastic leukemia viral oncogene homolog 3 autocrine loop contributes to invasion and early recurrence of human hepatoma.

Hsieh SY, He JR, Hsu CY, Chen WJ, Bera R, Lin KY, Shih TC, Yu MC, Lin YJ, Chang CJ, Weng WH, Huang SF.

Hepatology. 2011 Feb;53(2):504-16. doi: 10.1002/hep.24083. Epub 2011 Jan 18.

PMID:
21246584
[PubMed - indexed for MEDLINE]
3.

Hematogenous metastasis of ovarian cancer: rethinking mode of spread.

Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK.

Cancer Cell. 2014 Jul 14;26(1):77-91. doi: 10.1016/j.ccr.2014.05.002.

PMID:
25026212
[PubMed - indexed for MEDLINE]
4.

NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation.

Buac K, Xu M, Cronin J, Weeraratna AT, Hewitt SM, Pavan WJ.

Pigment Cell Melanoma Res. 2009 Dec;22(6):773-84. doi: 10.1111/j.1755-148X.2009.00616.x. Epub 2009 Jul 30.

PMID:
19659570
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

An ERBB3/ERBB2 oncogenic unit plays a key role in NRG1 signaling and melanoma cell growth and survival.

Zhang K, Wong P, Duan J, Jacobs B, Borden EC, Bedogni B.

Pigment Cell Melanoma Res. 2013 May;26(3):408-14. doi: 10.1111/pcmr.12089. Epub 2013 Apr 2. Erratum in: Pigment Cell Melanoma Res. 2013 Jul;26(4):601.

PMID:
23480537
[PubMed - indexed for MEDLINE]
6.

The therapeutic potential of targeting the EGFR family in epithelial ovarian cancer.

Sheng Q, Liu J.

Br J Cancer. 2011 Apr 12;104(8):1241-5. doi: 10.1038/bjc.2011.62. Epub 2011 Mar 1. Review.

PMID:
21364581
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Constitutive activation of neuregulin/ERBB3 signaling pathway in clear cell sarcoma of soft tissue.

Schaefer KL, Brachwitz K, Braun Y, Diallo R, Wai DH, Zahn S, Schneider DT, Kuhnen C, Vollmann A, Brockhoff G, Gabbert HE, Poremba C.

Neoplasia. 2006 Jul;8(7):613-22.

PMID:
16867224
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

P2Y2 nucleotide receptors mediate metalloprotease-dependent phosphorylation of epidermal growth factor receptor and ErbB3 in human salivary gland cells.

Ratchford AM, Baker OJ, Camden JM, Rikka S, Petris MJ, Seye CI, Erb L, Weisman GA.

J Biol Chem. 2010 Mar 5;285(10):7545-55. doi: 10.1074/jbc.M109.078170. Epub 2010 Jan 11.

PMID:
20064929
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Autocrine activation of ErbB2/ErbB3 receptor complex by NRG-1 in non-small cell lung cancer cell lines.

Gollamudi M, Nethery D, Liu J, Kern JA.

Lung Cancer. 2004 Feb;43(2):135-43.

PMID:
14739033
[PubMed - indexed for MEDLINE]
10.

An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models.

Xia W, Petricoin EF 3rd, Zhao S, Liu L, Osada T, Cheng Q, Wulfkuhle JD, Gwin WR, Yang X, Gallagher RI, Bacus S, Lyerly HK, Spector NL.

Breast Cancer Res. 2013;15(5):R85.

PMID:
24044505
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis.

Smirnova T, Zhou ZN, Flinn RJ, Wyckoff J, Boimel PJ, Pozzuto M, Coniglio SJ, Backer JM, Bresnick AR, Condeelis JS, Hynes NE, Segall JE.

Oncogene. 2012 Feb 9;31(6):706-15. doi: 10.1038/onc.2011.275. Epub 2011 Jul 4.

PMID:
21725367
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling.

Ieguchi K, Fujita M, Ma Z, Davari P, Taniguchi Y, Sekiguchi K, Wang B, Takada YK, Takada Y.

J Biol Chem. 2010 Oct 8;285(41):31388-98. doi: 10.1074/jbc.M110.113878. Epub 2010 Aug 3.

PMID:
20682778
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Targeting ErbB3-mediated stromal-epithelial interactions in pancreatic ductal adenocarcinoma.

Liles JS, Arnoletti JP, Kossenkov AV, Mikhaylina A, Frost AR, Kulesza P, Heslin MJ, Frolov A.

Br J Cancer. 2011 Aug 9;105(4):523-33. doi: 10.1038/bjc.2011.263. Epub 2011 Jul 26.

PMID:
21792199
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Association between growth factor heregulin1α and receptors in growth of ovarian cancer cell line with high potentiality of peritoneal dissemination.

Nishiyama H, Soeda S, Watanabe T, Fujimori K.

Fukushima J Med Sci. 2012;58(1):22-32.

PMID:
22790889
[PubMed - indexed for MEDLINE]
Free Article
15.

Constitutive neuregulin-1/ErbB signaling contributes to human vestibular schwannoma proliferation.

Hansen MR, Roehm PC, Chatterjee P, Green SH.

Glia. 2006 Apr 15;53(6):593-600.

PMID:
16432850
[PubMed - indexed for MEDLINE]
16.

Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells.

Ueno Y, Sakurai H, Tsunoda S, Choo MK, Matsuo M, Koizumi K, Saiki I.

Int J Cancer. 2008 Jul 15;123(2):340-7. doi: 10.1002/ijc.23465.

PMID:
18398842
[PubMed - indexed for MEDLINE]
17.

Significance of integrin αvβ5 and erbB3 in enhanced cell migration and liver metastasis of colon carcinomas stimulated by hepatocyte-derived heregulin.

Yoshioka T, Nishikawa Y, Ito R, Kawamata M, Doi Y, Yamamoto Y, Yoshida M, Omori Y, Kotanagi H, Masuko T, Enomoto K.

Cancer Sci. 2010 Sep;101(9):2011-8. doi: 10.1111/j.1349-7006.2010.01640.x.

PMID:
20626753
[PubMed - indexed for MEDLINE]
18.

Novel anti-ErbB3 monoclonal antibodies show therapeutic efficacy in xenografted and spontaneous mouse tumors.

Aurisicchio L, Marra E, Luberto L, Carlomosti F, De Vitis C, Noto A, Gunes Z, Roscilli G, Mesiti G, Mancini R, Alimandi M, Ciliberto G.

J Cell Physiol. 2012 Oct;227(10):3381-8. doi: 10.1002/jcp.24037.

PMID:
22213458
[PubMed - indexed for MEDLINE]
19.

The neuregulin-I/ErbB signaling system in development and disease.

Britsch S.

Adv Anat Embryol Cell Biol. 2007;190:1-65. Review.

PMID:
17432114
[PubMed - indexed for MEDLINE]
20.

Neuregulin expression, function, and signaling in human ovarian cancer cells.

Gilmour LM, Macleod KG, McCaig A, Sewell JM, Gullick WJ, Smyth JF, Langdon SP.

Clin Cancer Res. 2002 Dec;8(12):3933-42.

PMID:
12473609
[PubMed - indexed for MEDLINE]
Free Article
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