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Items: 1 to 20 of 106

1.

Role of the chromobox protein CBX7 in lymphomagenesis.

Scott CL, Gil J, Hernando E, Teruya-Feldstein J, Narita M, Martínez D, Visakorpi T, Mu D, Cordon-Cardo C, Peters G, Beach D, Lowe SW.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5389-94. Epub 2007 Mar 20.

2.

Oncogenic role of the chromobox protein CBX7 in gastric cancer.

Zhang XW, Zhang L, Qin W, Yao XH, Zheng LZ, Liu X, Li J, Guo WJ.

J Exp Clin Cancer Res. 2010 Aug 19;29:114. doi: 10.1186/1756-9966-29-114.

3.

Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a.

Yap KL, Li S, Muñoz-Cabello AM, Raguz S, Zeng L, Mujtaba S, Gil J, Walsh MJ, Zhou MM.

Mol Cell. 2010 Jun 11;38(5):662-74. doi: 10.1016/j.molcel.2010.03.021.

4.

CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus.

Bernard D, Martinez-Leal JF, Rizzo S, Martinez D, Hudson D, Visakorpi T, Peters G, Carnero A, Beach D, Gil J.

Oncogene. 2005 Aug 25;24(36):5543-51.

PMID:
15897876
5.

Polycomb CBX7 has a unifying role in cellular lifespan.

Gil J, Bernard D, Martínez D, Beach D.

Nat Cell Biol. 2004 Jan;6(1):67-72. Epub 2003 Nov 30.

PMID:
14647293
6.

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

Jacobs JJ, Scheijen B, Voncken JW, Kieboom K, Berns A, van Lohuizen M.

Genes Dev. 1999 Oct 15;13(20):2678-90.

7.

Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence.

Agherbi H, Gaussmann-Wenger A, Verthuy C, Chasson L, Serrano M, Djabali M.

PLoS One. 2009 May 20;4(5):e5622. doi: 10.1371/journal.pone.0005622.

8.

A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1.

Negishi M, Saraya A, Mochizuki S, Helin K, Koseki H, Iwama A.

PLoS One. 2010 Aug 24;5(8):e12373. doi: 10.1371/journal.pone.0012373.

9.

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.

Itahana K, Zou Y, Itahana Y, Martinez JL, Beausejour C, Jacobs JJ, Van Lohuizen M, Band V, Campisi J, Dimri GP.

Mol Cell Biol. 2003 Jan;23(1):389-401.

10.

Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice.

Chiba T, Seki A, Aoki R, Ichikawa H, Negishi M, Miyagi S, Oguro H, Saraya A, Kamiya A, Nakauchi H, Yokosuka O, Iwama A.

Hepatology. 2010 Sep;52(3):1111-23. doi: 10.1002/hep.23793.

PMID:
20648475
11.
12.

CBX7 inhibits breast tumorigenicity through DKK-1-mediated suppression of the Wnt/β-catenin pathway.

Kim HY, Park JH, Won HY, Lee JY, Kong G.

FASEB J. 2015 Jan;29(1):300-13. doi: 10.1096/fj.14-253997. Epub 2014 Oct 28.

13.

USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathway.

Liu YL, Jiang SX, Yang YM, Xu H, Liu JL, Wang XS.

Cell Biochem Biophys. 2012 Jan;62(1):229-35. doi: 10.1007/s12013-011-9287-0.

PMID:
21928107
14.

Polycomb CBX7 directly controls trimethylation of histone H3 at lysine 9 at the p16 locus.

Li Q, Wang X, Lu Z, Zhang B, Guan Z, Liu Z, Zhong Q, Gu L, Zhou J, Zhu B, Ji J, Deng D.

PLoS One. 2010 Oct 29;5(10):e13732. doi: 10.1371/journal.pone.0013732.

15.

Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.

Eischen CM, Roussel MF, Korsmeyer SJ, Cleveland JL.

Mol Cell Biol. 2001 Nov;21(22):7653-62.

16.

FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression.

Li SK, Smith DK, Leung WY, Cheung AM, Lam EW, Dimri GP, Yao KM.

J Biol Chem. 2008 Jun 13;283(24):16545-53. doi: 10.1074/jbc.M709604200. Epub 2008 Apr 11.

17.

Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development.

Eischen CM, Alt JR, Wang P.

Oncogene. 2004 Nov 25;23(55):8931-40.

PMID:
15467748
18.

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.

Bracken AP, Kleine-Kohlbrecher D, Dietrich N, Pasini D, Gargiulo G, Beekman C, Theilgaard-Mönch K, Minucci S, Porse BT, Marine JC, Hansen KH, Helin K.

Genes Dev. 2007 Mar 1;21(5):525-30.

19.

Dual inactivation of RB and p53 pathways in RAS-induced melanomas.

Bardeesy N, Bastian BC, Hezel A, Pinkel D, DePinho RA, Chin L.

Mol Cell Biol. 2001 Mar;21(6):2144-53.

20.

A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis.

Berg T, Thoene S, Yap D, Wee T, Schoeler N, Rosten P, Lim E, Bilenky M, Mungall AJ, Oellerich T, Lee S, Lai CK, Umlandt P, Salmi A, Chang H, Yue L, Lai D, Cheng SW, Morin RD, Hirst M, Serve H, Marra MA, Morin GB, Gascoyne RD, Aparicio SA, Humphries RK.

Blood. 2014 Jun 19;123(25):3914-24. doi: 10.1182/blood-2012-12-473439. Epub 2014 May 6.

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