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Results: 1 to 20 of 24

1.

Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening.

Bialkowska AB, Crisp M, Bannister T, He Y, Chowdhury S, Schürer S, Chase P, Spicer T, Madoux F, Tian C, Hodder P, Zaharevitz D, Yang VW.

Mol Cancer Ther. 2011 Nov;10(11):2043-51. doi: 10.1158/1535-7163.MCT-11-0550. Epub 2011 Sep 1.

PMID:
21885866
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Minimum information about a bioactive entity (MIABE).

Orchard S, Al-Lazikani B, Bryant S, Clark D, Calder E, Dix I, Engkvist O, Forster M, Gaulton A, Gilson M, Glen R, Grigorov M, Hammond-Kosack K, Harland L, Hopkins A, Larminie C, Lynch N, Mann RK, Murray-Rust P, Lo Piparo E, Southan C, Steinbeck C, Wishart D, Hermjakob H, Overington J, Thornton J.

Nat Rev Drug Discov. 2011 Aug 31;10(9):661-9. doi: 10.1038/nrd3503. Review.

PMID:
21878981
[PubMed - indexed for MEDLINE]
3.

BioAssay Ontology (BAO): a semantic description of bioassays and high-throughput screening results.

Visser U, Abeyruwan S, Vempati U, Smith RP, Lemmon V, Schürer SC.

BMC Bioinformatics. 2011 Jun 24;12:257. doi: 10.1186/1471-2105-12-257.

PMID:
21702939
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

BioPortal: enhanced functionality via new Web services from the National Center for Biomedical Ontology to access and use ontologies in software applications.

Whetzel PL, Noy NF, Shah NH, Alexander PR, Nyulas C, Tudorache T, Musen MA.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W541-5. doi: 10.1093/nar/gkr469. Epub 2011 Jun 14.

PMID:
21672956
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets.

Schürer SC, Vempati U, Smith R, Southern M, Lemmon V.

J Biomol Screen. 2011 Apr;16(4):415-26. doi: 10.1177/1087057111400191.

PMID:
21471461
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Modeling biomedical experimental processes with OBI.

Brinkman RR, Courtot M, Derom D, Fostel JM, He Y, Lord P, Malone J, Parkinson H, Peters B, Rocca-Serra P, Ruttenberg A, Sansone SA, Soldatova LN, Stoeckert CJ Jr, Turner JA, Zheng J; OBI consortium.

J Biomed Semantics. 2010 Jun 22;1 Suppl 1:S7. doi: 10.1186/2041-1480-1-S1-S7.

PMID:
20626927
[PubMed]
Free PMC Article
7.

OntoFox: web-based support for ontology reuse.

Xiang Z, Courtot M, Brinkman RR, Ruttenberg A, He Y.

BMC Res Notes. 2010 Jun 22;3:175. doi: 10.1186/1756-0500-3-175.

PMID:
20569493
[PubMed]
Free PMC Article
8.

New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays.

Baell JB, Holloway GA.

J Med Chem. 2010 Apr 8;53(7):2719-40. doi: 10.1021/jm901137j.

PMID:
20131845
[PubMed - indexed for MEDLINE]
9.

Novel trends in high-throughput screening.

Mayr LM, Bojanic D.

Curr Opin Pharmacol. 2009 Oct;9(5):580-8. doi: 10.1016/j.coph.2009.08.004. Epub 2009 Sep 21. Review.

PMID:
19775937
[PubMed - indexed for MEDLINE]
10.

PubChem: a public information system for analyzing bioactivities of small molecules.

Wang Y, Xiao J, Suzek TO, Zhang J, Wang J, Bryant SH.

Nucleic Acids Res. 2009 Jul;37(Web Server issue):W623-33. doi: 10.1093/nar/gkp456. Epub 2009 Jun 4.

PMID:
19498078
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations.

Du P, Feng G, Flatow J, Song J, Holko M, Kibbe WA, Lin SM.

Bioinformatics. 2009 Jun 15;25(12):i63-8. doi: 10.1093/bioinformatics/btp193.

PMID:
19478018
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Promiscuous aggregate-based inhibitors promote enzyme unfolding.

Coan KE, Maltby DA, Burlingame AL, Shoichet BK.

J Med Chem. 2009 Apr 9;52(7):2067-75. doi: 10.1021/jm801605r.

PMID:
19281222
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A bioinformatics analysis of the cell line nomenclature.

Sarntivijai S, Ade AS, Athey BD, States DJ.

Bioinformatics. 2008 Dec 1;24(23):2760-6. doi: 10.1093/bioinformatics/btn502. Epub 2008 Oct 10.

PMID:
18849319
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration.

Smith B, Ashburner M, Rosse C, Bard J, Bug W, Ceusters W, Goldberg LJ, Eilbeck K, Ireland A, Mungall CJ; OBI Consortium, Leontis N, Rocca-Serra P, Ruttenberg A, Sansone SA, Scheuermann RH, Shah N, Whetzel PL, Lewis S.

Nat Biotechnol. 2007 Nov;25(11):1251-5.

PMID:
17989687
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Reporting data from high-throughput screening of small-molecule libraries.

Inglese J, Shamu CE, Guy RK.

Nat Chem Biol. 2007 Aug;3(8):438-41.

PMID:
17637769
[PubMed - indexed for MEDLINE]
16.

A detergent-based assay for the detection of promiscuous inhibitors.

Feng BY, Shoichet BK.

Nat Protoc. 2006;1(2):550-3.

PMID:
17191086
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. Epub 2006 Jul 24.

PMID:
16864780
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The MGED Ontology: a resource for semantics-based description of microarray experiments.

Whetzel PL, Parkinson H, Causton HC, Fan L, Fostel J, Fragoso G, Game L, Heiskanen M, Morrison N, Rocca-Serra P, Sansone SA, Taylor C, White J, Stoeckert CJ Jr.

Bioinformatics. 2006 Apr 1;22(7):866-73. Epub 2006 Jan 21.

PMID:
16428806
[PubMed - indexed for MEDLINE]
Free Article
19.

High-throughput screening-driven lead discovery: meeting the challenges of finding new therapeutics.

Posner BA.

Curr Opin Drug Discov Devel. 2005 Jul;8(4):487-94. Review.

PMID:
16022185
[PubMed - indexed for MEDLINE]
20.

NIH Molecular Libraries Initiative.

Austin CP, Brady LS, Insel TR, Collins FS.

Science. 2004 Nov 12;306(5699):1138-9. No abstract available.

PMID:
15542455
[PubMed - indexed for MEDLINE]

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