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Results: 1 to 20 of 225

1.

In search of the tumour-suppressor functions of BRCA1 and BRCA2.

Scully R, Livingston DM.

Nature. 2000 Nov 23;408(6811):429-32.

PMID:
11100717
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination.

Nakamura S, Roth JA, Mukhopadhyay T.

Mol Cell Biol. 2000 Dec;20(24):9391-8.

PMID:
11094089
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Regulation of p53 activity in nuclear bodies by a specific PML isoform.

Fogal V, Gostissa M, Sandy P, Zacchi P, Sternsdorf T, Jensen K, Pandolfi PP, Will H, Schneider C, Del Sal G.

EMBO J. 2000 Nov 15;19(22):6185-95.

PMID:
11080164
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

Ries S, Biederer C, Woods D, Shifman O, Shirasawa S, Sasazuki T, McMahon M, Oren M, McCormick F.

Cell. 2000 Oct 13;103(2):321-30.

PMID:
11057904
[PubMed - indexed for MEDLINE]
Free Article
5.

A role for the polyproline domain of p53 in its regulation by Mdm2.

Berger M, Vogt Sionov R, Levine AJ, Haupt Y.

J Biol Chem. 2001 Feb 9;276(6):3785-90. Epub 2000 Oct 26.

PMID:
11053443
[PubMed - indexed for MEDLINE]
Free Article
6.

Defying death after DNA damage.

Rich T, Allen RL, Wyllie AH.

Nature. 2000 Oct 12;407(6805):777-83. Review.

PMID:
11048728
[PubMed - indexed for MEDLINE]
7.

Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation.

Rodriguez MS, Desterro JM, Lain S, Lane DP, Hay RT.

Mol Cell Biol. 2000 Nov;20(22):8458-67.

PMID:
11046142
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Role for the p53 homologue p73 in E2F-1-induced apoptosis.

Irwin M, Marin MC, Phillips AC, Seelan RS, Smith DI, Liu W, Flores ER, Tsai KY, Jacks T, Vousden KH, Kaelin WG Jr.

Nature. 2000 Oct 5;407(6804):645-8.

PMID:
11034215
[PubMed - indexed for MEDLINE]
9.

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53.

Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T, Nishimori H, Tamai K, Tokino T, Nakamura Y, Taya Y.

Cell. 2000 Sep 15;102(6):849-62.

PMID:
11030628
[PubMed - indexed for MEDLINE]
Free Article
10.

The function of PML in p53-dependent apoptosis.

Guo A, Salomoni P, Luo J, Shih A, Zhong S, Gu W, Pandolfi PP.

Nat Cell Biol. 2000 Oct;2(10):730-6.

PMID:
11025664
[PubMed - indexed for MEDLINE]
11.

p53 is associated with cellular microtubules and is transported to the nucleus by dynein.

Giannakakou P, Sackett DL, Ward Y, Webster KR, Blagosklonny MV, Fojo T.

Nat Cell Biol. 2000 Oct;2(10):709-17.

PMID:
11025661
[PubMed - indexed for MEDLINE]
12.

p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect.

Blagosklonny MV.

FASEB J. 2000 Oct;14(13):1901-7. Review.

PMID:
11023974
[PubMed - indexed for MEDLINE]
Free Article
13.

Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study.

Lev Bar-Or R, Maya R, Segel LA, Alon U, Levine AJ, Oren M.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11250-5.

PMID:
11016968
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The MDM2 RING-finger domain is required to promote p53 nuclear export.

Geyer RK, Yu ZK, Maki CG.

Nat Cell Biol. 2000 Sep;2(9):569-73.

PMID:
10980696
[PubMed - indexed for MEDLINE]
15.

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

Boyd SD, Tsai KY, Jacks T.

Nat Cell Biol. 2000 Sep;2(9):563-8.

PMID:
10980695
[PubMed - indexed for MEDLINE]
16.

Mdm2 inhibits the apoptotic function of p53 mainly by targeting it for degradation.

Yap DB, Hsieh JK, Lu X.

J Biol Chem. 2000 Nov 24;275(47):37296-302.

PMID:
10980197
[PubMed - indexed for MEDLINE]
Free Article
17.

Modulation of transcriptional activity of p53 by ultraviolet radiation: linkage between p53 pathway and DNA repair through damage recognition.

Zhu Q, Wani MA, El-Mahdy M, Wani G, Wani AA.

Mol Carcinog. 2000 Aug;28(4):215-24.

PMID:
10972991
[PubMed - indexed for MEDLINE]
18.

Synergistic activation of p53-dependent transcription by two cooperating damage recognition pathways.

Blaydes JP, Craig AL, Wallace M, Ball HM, Traynor NJ, Gibbs NK, Hupp TR.

Oncogene. 2000 Aug 10;19(34):3829-39.

PMID:
10951576
[PubMed - indexed for MEDLINE]
Free Article
19.

Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress.

Ljungman M.

Neoplasia. 2000 May-Jun;2(3):208-25. Review.

PMID:
10935507
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mice without telomerase: what can they teach us about human cancer?

Artandi SE, DePinho RA.

Nat Med. 2000 Aug;6(8):852-5. Review.

PMID:
10932211
[PubMed - indexed for MEDLINE]

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