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Results: 1 to 20 of 301

1.

Valnoctamide, a non-teratogenic amide derivative of valproic acid, inhibits arachidonic acid activation in vitro by recombinant acyl-CoA synthetase-4.

Modi HR, Basselin M, Rapoport SI.

Bipolar Disord. 2014 Jul 8. doi: 10.1111/bdi.12220. [Epub ahead of print]

PMID:
25041123
[PubMed - as supplied by publisher]
2.

Effects of valproic acid on gene expression during human embryonic stem cell differentiation into neurons.

Ehashi T, Suzuki N, Ando S, Sumida K, Saito K.

J Toxicol Sci. 2014 Jun;39(3):383-90.

PMID:
24849673
[PubMed - in process]
Free Article
3.

Developmental cardiotoxicity effects of four commonly used antiepileptic drugs in embryonic chick heart micromass culture and embryonic stem cell culture systems.

Ahir BK, Pratten MK.

Toxicol In Vitro. 2014 Aug;28(5):948-60. doi: 10.1016/j.tiv.2014.04.001. Epub 2014 Apr 24.

PMID:
24768975
[PubMed - in process]
4.

Teratogenic Activity of HDAC Inhibitors.

Giavini E, Menegola E.

Curr Pharm Des. 2014 Feb 5. [Epub ahead of print]

PMID:
24502598
[PubMed - as supplied by publisher]
5.

Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.

Waldmann T, Rempel E, Balmer NV, König A, Kolde R, Gaspar JA, Henry M, Hescheler J, Sachinidis A, Rahnenführer J, Hengstler JG, Leist M.

Chem Res Toxicol. 2014 Mar 17;27(3):408-20. doi: 10.1021/tx400402j. Epub 2014 Jan 21.

PMID:
24383497
[PubMed - in process]
Free PMC Article
6.

Hypotonia and poor feeding in an infant exposed to lamotrigine and valproic acid in utero.

Takcı S, Bayhan C, Celik T, Yiğit S.

Turk J Pediatr. 2013 Sep-Oct;55(5):546-8.

PMID:
24382540
[PubMed - in process]
Free Article
7.

Teratogenic potential of antiepileptic drugs in the zebrafish model.

Lee SH, Kang JW, Lin T, Lee JE, Jin DI.

Biomed Res Int. 2013;2013:726478. doi: 10.1155/2013/726478. Epub 2013 Nov 14.

PMID:
24324971
[PubMed - in process]
Free PMC Article
8.

Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.

Shekh-Ahmad T, Hen N, Yagen B, McDonough JH, Finnell RH, Wlodarczyk BJ, Bialer M.

Epilepsia. 2014 Feb;55(2):353-61. doi: 10.1111/epi.12480. Epub 2013 Dec 6.

PMID:
24313671
[PubMed - indexed for MEDLINE]
9.

Developmental exposure to valproic acid alters the expression of microRNAs involved in neurodevelopment in zebrafish.

Aluru N, Deak KL, Jenny MJ, Hahn ME.

Neurotoxicol Teratol. 2013 Nov-Dec;40:46-58. doi: 10.1016/j.ntt.2013.10.001. Epub 2013 Oct 12.

PMID:
24126255
[PubMed - in process]
10.

Teratology study of amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide in NMRI mice.

Onishi Y, Okada A, Noyori H, Okamura A, Hen N, Yagen B, Bialer M, Fujiwara M.

Birth Defects Res B Dev Reprod Toxicol. 2013 Aug;98(4):318-27. doi: 10.1002/bdrb.21068. Epub 2013 Aug 26.

PMID:
24039104
[PubMed - indexed for MEDLINE]
11.

Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET.

Kim SW, Hooker JM, Otto N, Win K, Muench L, Shea C, Carter P, King P, Reid AE, Volkow ND, Fowler JS.

Nucl Med Biol. 2013 Oct;40(7):912-8. doi: 10.1016/j.nucmedbio.2013.06.007. Epub 2013 Jul 29.

PMID:
23906667
[PubMed - indexed for MEDLINE]
12.

Identifying associations between maternal medication use and birth defects using a case-population approach: an exploratory study on signal detection.

de Jonge L, Zetstra-van der Woude PA, Bos HJ, de Jong-van den Berg LT, Bakker MK.

Drug Saf. 2013 Nov;36(11):1069-78. doi: 10.1007/s40264-013-0082-2.

PMID:
23828658
[PubMed - indexed for MEDLINE]
13.

Inhibition of nitric oxide synthesis enhances teratogenic effects induced by valproic Acid.

Tiboni GM, Chiarelli F, Verrotti A.

In Vivo. 2013 Jul-Aug;27(4):513-8.

PMID:
23812222
[PubMed - indexed for MEDLINE]
14.

Arrhenius thermodynamics and birth defects: chemical teratogen synergy. Untested, testable, and projected relevance.

Miller MW, Church CC.

Birth Defects Res C Embryo Today. 2013 Mar;99(1):50-60. doi: 10.1002/bdrc.21025. Review.

PMID:
23723172
[PubMed - indexed for MEDLINE]
15.

Histone acetylation in neurodevelopment.

Contestabile A, Sintoni S.

Curr Pharm Des. 2013;19(28):5043-50. Review.

PMID:
23448460
[PubMed - indexed for MEDLINE]
16.

Propylisopropylacetic acid (PIA), a constitutional isomer of valproic acid, uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: a potential drug for bipolar disorder.

Modi HR, Basselin M, Taha AY, Li LO, Coleman RA, Bialer M, Rapoport SI.

Biochim Biophys Acta. 2013 Apr;1831(4):880-6. doi: 10.1016/j.bbalip.2013.01.008. Epub 2013 Jan 23.

PMID:
23354024
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Antiepileptic drugs (AEDs) during pregnancy and risk of congenital jaw and oral malformation.

Koo J, Zavras A.

Oral Dis. 2013 Oct;19(7):712-20. doi: 10.1111/odi.12061. Epub 2013 Jan 11.

PMID:
23305414
[PubMed - in process]
18.

Sodium valproate exposure during the brain growth spurt transiently impairs spatial learning in prepubertal rats.

Filgueiras CC, Pohl-Guimarães F, Krahe TE, Medina AE.

Pharmacol Biochem Behav. 2013 Jan;103(3):684-91. doi: 10.1016/j.pbb.2012.11.007. Epub 2012 Nov 21.

PMID:
23178315
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Characterisation of a neural teratogenicity assay based on human ESCs differentiation following exposure to valproic acid.

Colleoni S, Galli C, Gaspar JA, Meganathan K, Jagtap S, Hescheler J, Sachinidis A, Lazzari G.

Curr Med Chem. 2012;19(35):6065-71.

PMID:
23061626
[PubMed - indexed for MEDLINE]
20.

Reduction in valproic acid-induced neural tube defects by maternal immune stimulation: role of apoptosis.

Mallela M, Hrubec T.

Birth Defects Res B Dev Reprod Toxicol. 2012 Aug;95(4):296-303. doi: 10.1002/bdrb.21018. Epub 2012 Jul 5.

PMID:
22767483
[PubMed - indexed for MEDLINE]

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