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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 2
1979 13
1980 6
1981 8
1982 13
1983 12
1984 3
1985 10
1986 4
1987 16
1988 17
1989 19
1990 23
1991 20
1992 24
1993 21
1994 27
1995 36
1996 14
1997 21
1998 24
1999 21
2000 15
2001 22
2002 17
2003 25
2004 31
2005 17
2006 14
2007 20
2008 20
2009 16
2010 18
2011 16
2012 19
2013 18
2014 12
2015 8
2016 17
2017 10
2018 4
2019 5
2020 7
2021 10
2022 9
2023 9
2024 3

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683 results

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Page 1
Postpartum haemorrhage: prevention and treatment.
Sentilhes L, Merlot B, Madar H, Sztark F, Brun S, Deneux-Tharaux C. Sentilhes L, et al. Expert Rev Hematol. 2016 Nov;9(11):1043-1061. doi: 10.1080/17474086.2016.1245135. Epub 2016 Oct 20. Expert Rev Hematol. 2016. PMID: 27701915 Review.
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.
Tao X, Zhang R, Du R, Yu T, Yang H, Li J, Wang Y, Liu Q, Zuo S, Wang X, Lazarus M, Zhou L, Wang B, Yu Y, Shen Y. Tao X, et al. J Exp Med. 2022 May 2;219(5):e20212414. doi: 10.1084/jem.20212414. Epub 2022 Apr 14. J Exp Med. 2022. PMID: 35420633 Free PMC article.
EP3 upregulated Itga4 expression in NK cells through promoting Spic nuclear translocation via PKC-mediated phosphorylation of Spic at T191. Activation of EP3 by sulprostone alleviated CCL4-induced liver fibrosis in mice. Thus, EP3 is required for adhesion and cytotoxicity …
EP3 upregulated Itga4 expression in NK cells through promoting Spic nuclear translocation via PKC-mediated phosphorylation of Spic at T191. …
Major obstetric hemorrhage.
Le Gouez A, Mercier FJ. Le Gouez A, et al. Transfus Clin Biol. 2016 Nov;23(4):229-232. doi: 10.1016/j.tracli.2016.08.003. Epub 2016 Aug 31. Transfus Clin Biol. 2016. PMID: 27592155
The etiologies in antenatal or postpartum must be well-known in order to be treated adequately. A rapid recourse to prostaglandins (sulprostone in France) may reverse uterine atony. Invasive approach with surgery or radiology should be promptly implemented (uterine artery …
The etiologies in antenatal or postpartum must be well-known in order to be treated adequately. A rapid recourse to prostaglandins (sulpr …
Efficacy of early intrauterine balloon tamponade for immediate postpartum hemorrhage after vaginal delivery: a randomized clinical trial.
Rozenberg P, Sentilhes L, Goffinet F, Vayssiere C, Senat MV, Haddad B, Morel O, Garabedian C, Vivanti A, Perrotin F, Kayem G, Azria E, Raynal P, Verspyck E, Sananes N, Gallot D, Bretelle F, Seco A, Winer N, Deneux-Tharaux C; Groupe de Recherche en Obstétrique et Gynécologie. Rozenberg P, et al. Am J Obstet Gynecol. 2023 Nov;229(5):542.e1-542.e14. doi: 10.1016/j.ajog.2023.05.014. Epub 2023 May 18. Am J Obstet Gynecol. 2023. PMID: 37209893 Clinical Trial.
The inclusion criteria were a postpartum hemorrhage refractory to first-line uterotonics (oxytocin) and requiring a second-line uterotonic treatment with sulprostone (E1 prostaglandin). In the study group, the sulprostone infusion was combined with intrauterine tamp …
The inclusion criteria were a postpartum hemorrhage refractory to first-line uterotonics (oxytocin) and requiring a second-line uterotonic t …
[Management of major postpartum hemorrhage].
Nebout S, Merbai N, Faitot V, Keita H. Nebout S, et al. Presse Med. 2014 Feb;43(2):111-7. doi: 10.1016/j.lpm.2013.06.026. Epub 2013 Dec 27. Presse Med. 2014. PMID: 24373716 Review. French.
In case of failure of the initial measures (oxytocin, manual placenta removal, uterus and birth canal examination), the management of severe forms includes active resuscitation (intravenous fluids, blood transfusion, vasoactive drugs), haemostatic interventions (sulprostone …
In case of failure of the initial measures (oxytocin, manual placenta removal, uterus and birth canal examination), the management of severe …
Prostaglandins for Postpartum Hemorrhage: Pharmacology, Application, and Current Opinion.
Chen Y, Jiang W, Zhao Y, Sun D, Zhang X, Wu F, Zheng C. Chen Y, et al. Pharmacology. 2021;106(9-10):477-487. doi: 10.1159/000516631. Epub 2021 Jul 8. Pharmacology. 2021. PMID: 34237742 Free article. Review.
SUMMARY: PG agents that are constantly used in clinical practice include carboprost, sulprostone, and misoprostol, representing the analogs of PGF2alpha, PGE2, and PGE1, respectively. ...
SUMMARY: PG agents that are constantly used in clinical practice include carboprost, sulprostone, and misoprostol, representing the a …
Prostaglandins in the eye: Function, expression, and roles in glaucoma.
Doucette LP, Walter MA. Doucette LP, et al. Ophthalmic Genet. 2017 Mar-Apr;38(2):108-116. doi: 10.3109/13816810.2016.1164193. Epub 2016 Apr 12. Ophthalmic Genet. 2017. PMID: 27070211 Review.
The currently used prostaglandin analogues (latanoprost, bimatoprost, tafluprost, and travoprost) mimic PGF2 and target one of the prostaglandin receptors (FP), though research into harnessing the other receptors using compounds like Sulprostone (EP3 receptor), or Iloprost …
The currently used prostaglandin analogues (latanoprost, bimatoprost, tafluprost, and travoprost) mimic PGF2 and target one of the prostagla …
Discovery and Optimization of 7-Alkylidenyltetrahydroindazole-Based Acylsulfonamide EP3 Antagonists.
Zhu B, Zhang X, Guo L, Rankin M, Bakaj I, Ho G, Lee SP, Norquay L, Macielag M. Zhu B, et al. ACS Med Chem Lett. 2021 Dec 7;13(1):111-117. doi: 10.1021/acsmedchemlett.1c00594. eCollection 2022 Jan 13. ACS Med Chem Lett. 2021. PMID: 35059130 Free PMC article.
In addition, compound 7 demonstrated in vivo activity in a rat ivGTT model, reversing the suppressive effect of the EP3-specific agonist sulprostone on glucose-stimulated insulin secretion. Further optimization to improve the pharmacokinetic profile led to the discovery of …
In addition, compound 7 demonstrated in vivo activity in a rat ivGTT model, reversing the suppressive effect of the EP3-specific agonist …
Sulprostone-Induced Gastric Dysrhythmia in the Ferret: Conventional and Advanced Analytical Approaches.
Lu Z, Zhou Y, Tu L, Chan SW, Ngan MP, Cui D, Liu YHJ, Huang IB, Kung JSC, Hui CMJ, Rudd JA. Lu Z, et al. Front Physiol. 2021 Jan 8;11:583082. doi: 10.3389/fphys.2020.583082. eCollection 2020. Front Physiol. 2021. PMID: 33488391 Free PMC article.
DFA revealed that sulprostone decreased the fluctuation function, indicative of a loss of the variability of GMA fluctuations around local trends. Sulprostone increased SampEn values, indicating a loss of regularity in the GMA data. ...
DFA revealed that sulprostone decreased the fluctuation function, indicative of a loss of the variability of GMA fluctuations around …
Prostaglandins and antiprogestins.
Bygdeman M, Swahn ML. Bygdeman M, et al. Acta Obstet Gynecol Scand Suppl. 1989;149:13-8. doi: 10.1111/j.1600-0412.1989.tb08043.x. Acta Obstet Gynecol Scand Suppl. 1989. PMID: 2618597
During the three weeks immediately following the first missed menstrual period, several prostaglandin (PG) analogs such as sulprostone, gemeprost and 9-methylene PGE2 have been used to terminate the pregnancy. ...Mifepristone (50 mg/day) followed by an intramuscular inject …
During the three weeks immediately following the first missed menstrual period, several prostaglandin (PG) analogs such as sulprostone …
683 results