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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 1
1962 1
1964 4
1965 4
1966 2
1967 2
1968 6
1969 6
1970 10
1971 7
1972 14
1973 9
1974 7
1975 18
1976 12
1977 11
1978 10
1979 15
1980 6
1981 8
1982 13
1983 12
1984 9
1985 12
1986 12
1987 9
1988 8
1989 7
1990 16
1991 13
1992 6
1993 10
1994 6
1995 7
1996 15
1997 17
1998 10
1999 5
2000 9
2001 10
2002 6
2003 10
2004 13
2005 10
2006 9
2007 20
2008 21
2009 26
2010 39
2011 26
2012 40
2013 52
2014 48
2015 76
2016 71
2017 74
2018 80
2019 68
2020 81
2021 100
2022 88
2023 66
2024 26

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1,276 results

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Page 1
Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.
Jensen T, Abdelmalek MF, Sullivan S, Nadeau KJ, Green M, Roncal C, Nakagawa T, Kuwabara M, Sato Y, Kang DH, Tolan DR, Sanchez-Lozada LG, Rosen HR, Lanaspa MA, Diehl AM, Johnson RJ. Jensen T, et al. J Hepatol. 2018 May;68(5):1063-1075. doi: 10.1016/j.jhep.2018.01.019. Epub 2018 Feb 2. J Hepatol. 2018. PMID: 29408694 Free PMC article. Review.
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome; its rising prevalence parallels the rise in obesity and diabetes. ...Recent evidence suggests that the predisposition to fatty liver is linked to the metaboli …
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome; its rising prevalence parallels …
Fructose- and sucrose- but not glucose-sweetened beverages promote hepatic de novo lipogenesis: A randomized controlled trial.
Geidl-Flueck B, Hochuli M, Németh Á, Eberl A, Derron N, Köfeler HC, Tappy L, Berneis K, Spinas GA, Gerber PA. Geidl-Flueck B, et al. J Hepatol. 2021 Jul;75(1):46-54. doi: 10.1016/j.jhep.2021.02.027. Epub 2021 Mar 6. J Hepatol. 2021. PMID: 33684506 Free article. Clinical Trial.
RESULTS: Daily intake of beverages sweetened with free fructose and fructose combined with glucose (sucrose) led to a 2-fold increase in basal hepatic fractional secretion rates (FSR) compared to control (median FSR %/day: sucrose 20.8 (p = 0.0015); fructose 19.7 (p …
RESULTS: Daily intake of beverages sweetened with free fructose and fructose combined with glucose (sucrose) led to a 2-fold increase …
Diet-Induced Models of Non-Alcoholic Fatty Liver Disease: Food for Thought on Sugar, Fat, and Cholesterol.
Eng JM, Estall JL. Eng JM, et al. Cells. 2021 Jul 16;10(7):1805. doi: 10.3390/cells10071805. Cells. 2021. PMID: 34359974 Free PMC article. Review.
Non-alcoholic fatty liver disease (NAFLD) affects approximately 1 in 4 people worldwide and is a major burden to health care systems. ...This review summarizes recent research comparing individual roles of major dietary components to NAFLD and addresses common misco …
Non-alcoholic fatty liver disease (NAFLD) affects approximately 1 in 4 people worldwide and is a major burden to health care s …
Exosomes from Short-Term High-Fat or High-Sucrose Fed Mice Induce Hepatic Steatosis through Different Pathways.
Castaño C, Novials A, Párrizas M. Castaño C, et al. Cells. 2022 Dec 31;12(1):169. doi: 10.3390/cells12010169. Cells. 2022. PMID: 36611962 Free PMC article.
Obesity and other closely associated diseases, such as metabolic-associated fatty liver disease (MAFLD) and type 2 diabetes, give rise to a common biometric and metabolic phenotype resulting from a different etiopathogenesis. To characterize the first stages of meta …
Obesity and other closely associated diseases, such as metabolic-associated fatty liver disease (MAFLD) and type 2 diabetes, g …
Sugar, uric acid, and the etiology of diabetes and obesity.
Johnson RJ, Nakagawa T, Sanchez-Lozada LG, Shafiu M, Sundaram S, Le M, Ishimoto T, Sautin YY, Lanaspa MA. Johnson RJ, et al. Diabetes. 2013 Oct;62(10):3307-15. doi: 10.2337/db12-1814. Diabetes. 2013. PMID: 24065788 Free PMC article. Review.
The intake of added sugars, such as from table sugar (sucrose) and high-fructose corn syrup has increased dramatically in the last hundred years and correlates closely with the rise in obesity, metabolic syndrome, and diabetes. ...
The intake of added sugars, such as from table sugar (sucrose) and high-fructose corn syrup has increased dramatically in the last hu …
The Buckwheat Iminosugar d-Fagomine Attenuates Sucrose-Induced Steatosis and Hypertension in Rats.
Ramos-Romero S, Hereu M, Atienza L, Amézqueta S, Casas J, Muñoz S, Medina I, Miralles-Pérez B, Romeu M, Torres JL. Ramos-Romero S, et al. Mol Nutr Food Res. 2020 Jan;64(1):e1900564. doi: 10.1002/mnfr.201900564. Epub 2019 Nov 22. Mol Nutr Food Res. 2020. PMID: 31657510 Free article.
The following are recorded: body weight; energy intake; glucose tolerance; plasma leptin concentration and lipid profile; populations of Bacteroidetes, Firmicutes, bacteroidales, clostridiales, enterobacteriales, and Escherichia coli in feces; blood pressure; urine uric acid and …
The following are recorded: body weight; energy intake; glucose tolerance; plasma leptin concentration and lipid profile; populations of Bac …
Chronic intake of high dietary sucrose induces sexually dimorphic metabolic adaptations in mouse liver and adipose tissue.
Stephenson EJ, Stayton AS, Sethuraman A, Rao PK, Meyer A, Gomes CK, Mulcahy MC, McAllan L, Puchowicz MA, Pierre JF, Bridges D, Han JC. Stephenson EJ, et al. Nat Commun. 2022 Oct 13;13(1):6062. doi: 10.1038/s41467-022-33840-6. Nat Commun. 2022. PMID: 36229459 Free PMC article.
Almost all effective treatments for non-alcoholic fatty liver disease (NAFLD) involve reduction of adiposity, which suggests the metabolic axis between liver and adipose tissue is essential to NAFLD development. ...We report that sucrose intake induces …
Almost all effective treatments for non-alcoholic fatty liver disease (NAFLD) involve reduction of adiposity, which suggests t …
SerpinA3N deficiency attenuates steatosis and enhances insulin signaling in male mice.
Tran M, Mostofa G, Picard M, Wu J, Wang L, Shin DJ. Tran M, et al. J Endocrinol. 2023 Feb 3;256(3):e220073. doi: 10.1530/JOE-22-0073. Print 2023 Mar 1. J Endocrinol. 2023. PMID: 36625462 Free PMC article.
Aberrant hepatic lipid metabolism is the major cause of non-alcoholic fatty liver disease (NAFLD) and is associated with insulin resistance and type 2 diabetes. ...SerpinA3N protein was markedly induced in mice with fatty livers. Hepatic deletion of SerpinA3N …
Aberrant hepatic lipid metabolism is the major cause of non-alcoholic fatty liver disease (NAFLD) and is associated with insul …
Lactose, Maltose, and Sucrose in Health and Disease.
Qi X, Tester RF. Qi X, et al. Mol Nutr Food Res. 2020 Apr;64(8):e1901082. doi: 10.1002/mnfr.201901082. Epub 2020 Apr 6. Mol Nutr Food Res. 2020. PMID: 32045507 Review.
SCOPE: This review represents a focus on the structure and properties of the common nutritional disaccharides (lactose, maltose, and sucrose) in health and disease. The aim is to provide a comprehensive reference source related to the role of disaccharides in human nutriti …
SCOPE: This review represents a focus on the structure and properties of the common nutritional disaccharides (lactose, maltose, and sucr …
Inulin intervention attenuates hepatic steatosis in rats via modulating gut microbiota and maintaining intestinal barrier function.
Yang Z, Su H, Lv Y, Tao H, Jiang Y, Ni Z, Peng L, Chen X. Yang Z, et al. Food Res Int. 2023 Jan;163:112309. doi: 10.1016/j.foodres.2022.112309. Epub 2022 Dec 7. Food Res Int. 2023. PMID: 36596207
Increasing evidence has suggested the mitigatory efficacy of prebiotic inulin on nonalcoholic fatty liver disease (NAFLD), nevertheless, its action mechanisms remain elusive. Herein, inulin consumption effectively ameliorated high-sucrose diet-induced hepatic …
Increasing evidence has suggested the mitigatory efficacy of prebiotic inulin on nonalcoholic fatty liver disease (NAFLD), nev …
1,276 results