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Prepubescent unilateral gynecomastia secondary to excessive soy consumption.
Sea JL, Abramyan M, Chiu HK. Sea JL, et al. J Pediatr Endocrinol Metab. 2020 Dec 14;34(4):521-525. doi: 10.1515/jpem-2020-0397. Print 2021 Apr 27. J Pediatr Endocrinol Metab. 2020. PMID: 33818045
To our knowledge, this is the first documented case of gynecomastia occurring in a prepubescent patient resulting from excessive intake of dietary soy. Importantly, we also report a complete resolution of gynecomastia upon exclusion of dietary products contai …
To our knowledge, this is the first documented case of gynecomastia occurring in a prepubescent patient resulting from excessive inta …
An unusual case of gynecomastia associated with soy product consumption.
Martinez J, Lewi JE. Martinez J, et al. Endocr Pract. 2008 May-Jun;14(4):415-8. doi: 10.4158/EP.14.4.415. Endocr Pract. 2008. PMID: 18558591
OBJECTIVE: To document a case of gynecomastia related to ingestion of soy products and review the literature. METHODS: We present the clinical course of a man with gynecomastia in relation to ingestion of 2 different soy products and review related lit …
OBJECTIVE: To document a case of gynecomastia related to ingestion of soy products and review the literature. METHODS: We pres …
Dietary soy protein containing isoflavonoids does not adversely affect the reproductive tract of male cynomolgus macaques (Macaca fascicularis).
Perry DL, Spedick JM, McCoy TP, Adams MR, Franke AA, Cline JM. Perry DL, et al. J Nutr. 2007 Jun;137(6):1390-4. doi: 10.1093/jn/137.6.1309. J Nutr. 2007. PMID: 17513396 Free article.
Ninety-one adult male cynomolgus macaques (Macaca fascicularis) were fed diets for 3 y differing only in protein source: 1) a soy-free, casein-lactalbumin-based diet or 2) a low-soy isoflavonoid diet ( approximately 6 mg . kg(-1) . d(-1)) or 3) a high-soy iso …
Ninety-one adult male cynomolgus macaques (Macaca fascicularis) were fed diets for 3 y differing only in protein source: 1) a soy-fre …
Soy protein formulas in children: no hormonal effects in long-term feeding.
Giampietro PG, Bruno G, Furcolo G, Casati A, Brunetti E, Spadoni GL, Galli E. Giampietro PG, et al. J Pediatr Endocrinol Metab. 2004 Feb;17(2):191-6. doi: 10.1515/jpem.2004.17.2.191. J Pediatr Endocrinol Metab. 2004. PMID: 15055353
Recently, the finding of high plasma concentration of phyto-oestrogens in soy protein formula (SPF) fed children has focused scientific attention on the phyto-oestrogens (isoflavones genistein, daidzein, and their glycosides) contained in SPFs. ...No abnormalities were obs …
Recently, the finding of high plasma concentration of phyto-oestrogens in soy protein formula (SPF) fed children has focused scientif …
Soybean isoflavone exposure does not have feminizing effects on men: a critical examination of the clinical evidence.
Messina M. Messina M. Fertil Steril. 2010 May 1;93(7):2095-104. doi: 10.1016/j.fertnstert.2010.03.002. Epub 2010 Apr 8. Fertil Steril. 2010. PMID: 20378106 Free article. Review.
OBJECTIVE: To critically evaluate the clinical evidence, and when not available, the animal data, most relevant to concerns that isoflavone exposure in the form of supplements or soy foods has feminizing effects on men. DESIGN: Medline literature review and cross-reference …
OBJECTIVE: To critically evaluate the clinical evidence, and when not available, the animal data, most relevant to concerns that isoflavone …
Secondary Hypogonadism due to Excessive Ingestion of Isoflavone in a Man.
Imai H, Nishikawa H, Suzuki A, Kodama E, Iida T, Mikura K, Hashizume M, Kigawa Y, Tadokoro R, Sugisawa C, Endo K, Iizaka T, Otsuka F, Nagasaka S. Imai H, et al. Intern Med. 2022 Oct 1;61(19):2899-2903. doi: 10.2169/internalmedicine.8578-21. Epub 2022 Feb 26. Intern Med. 2022. PMID: 35228414 Free PMC article.
A 54-year-old man had been drinking approximately 1.2 L of soy milk (equivalent to approximately 310 mg of isoflavones) per day for the previous 3 years. ...He stopped drinking soy milk on his own in June of that year. When he was admitted in August, blood tests sho …
A 54-year-old man had been drinking approximately 1.2 L of soy milk (equivalent to approximately 310 mg of isoflavones) per day for t …