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Possible role of resveratrol targeting estradiol and neprilysin pathways in lipopolysaccharide model of Alzheimer disease.
El-Sayed NS, Bayan Y. El-Sayed NS, et al. Adv Exp Med Biol. 2015;822:107-18. doi: 10.1007/978-3-319-08927-0_12. Adv Exp Med Biol. 2015. PMID: 25416980
Herbal extracts have been studied over the years for their potential therapeutic effect in AD. Resveratrol (RSV), one of the most important phytoestrogens, is considered to be useful as estrogen plays an important role in AD. One of the most important amyloid degrad …
Herbal extracts have been studied over the years for their potential therapeutic effect in AD. Resveratrol (RSV), one of the most imp …
Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF-kappaB/TNF-alpha signaling pathways: Experimental study.
Okan A, Doğanyiğit Z, Yilmaz S, Uçar S, Arikan Söylemez ES, Attar R. Okan A, et al. Cell Biochem Funct. 2023 Jun;41(4):423-433. doi: 10.1002/cbf.3790. Epub 2023 Mar 27. Cell Biochem Funct. 2023. PMID: 36970761
Twenty-eight male Spraque-Dawley rats were randomly divided into four groups (n = 7) as follows: control, lipopolysaccharide (LPS) (30 mg/kg dose), resveratrol, and LPS and resveratrol. ...LPS application caused severe tissue damage, oxidative stress, and inc …
Twenty-eight male Spraque-Dawley rats were randomly divided into four groups (n = 7) as follows: control, lipopolysaccharide (LPS) (3 …
Effects of resveratrol-related hydroxystilbenes on the nitric oxide production in macrophage cells: structural requirements and mechanism of action.
Cho DI, Koo NY, Chung WJ, Kim TS, Ryu SY, Im SY, Kim KM. Cho DI, et al. Life Sci. 2002 Sep 13;71(17):2071-82. doi: 10.1016/s0024-3205(02)01971-9. Life Sci. 2002. PMID: 12175900
NF-kappaB that plays an important role in iNOS expression is one of the targets of various potential anti-inflammatory agents including resveratrol. Resveratrol contains a structural similarity with estrogen, and there has been speculation about resveratro
NF-kappaB that plays an important role in iNOS expression is one of the targets of various potential anti-inflammatory agents includi …
Resveratrol inhibits cell apoptosis by suppressing long noncoding RNA (lncRNA) XLOC_014869 during lipopolysaccharide-induced acute lung injury in rats.
Jiang H, Wang S, Hou L, Huang JA, Su B. Jiang H, et al. J Thorac Dis. 2021 Nov;13(11):6409-6426. doi: 10.21037/jtd-21-1113. J Thorac Dis. 2021. PMID: 34992821 Free PMC article.
BACKGROUND: Acute lung injury (ALI) is a common clinical complication with a high mortality rate. Resveratrol (Res) has been shown to protect against ALI, but the role of long noncoding RNAs (lncRNAs) in this process is still unclear. METHODS: Male rats (n=20) aged …
BACKGROUND: Acute lung injury (ALI) is a common clinical complication with a high mortality rate. Resveratrol (Res) has been shown to …
The Possibility of Polygonum cuspidatum against Osteoarthritis based on Network Pharmacology.
Liu C, Yu L, Jiang Y, Gu S, Li C, Yin W, Zhou Z. Liu C, et al. Curr Comput Aided Drug Des. 2024;20(2):121-133. doi: 10.2174/1573409919666230403114131. Curr Comput Aided Drug Des. 2024. PMID: 37016525
BACKGROUND: Polygonum cuspidatum (PC), a widely used Chinese herbal medicine (CHM), plays an important role in treating various diseases including osteoarthritis (OA). ...RESULTS: PC was screened for nine potentially effective active compounds that can be used to …
BACKGROUND: Polygonum cuspidatum (PC), a widely used Chinese herbal medicine (CHM), plays an important role in treating var …