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The role of Akkermansia muciniphila in obesity, diabetes and atherosclerosis.
Hasani A, Ebrahimzadeh S, Hemmati F, Khabbaz A, Hasani A, Gholizadeh P. Hasani A, et al. J Med Microbiol. 2021 Oct;70(10). doi: 10.1099/jmm.0.001435. J Med Microbiol. 2021. PMID: 34623232 Review.
In this review, we focus on the role of A. muciniphila in diabetes, obesity and atherosclerosis, as well as the use of this bacterium as a next-generation probiotic. In regard to obesity and diabetes, human and animal trials have shown that A. muciniphila controls t …
In this review, we focus on the role of A. muciniphila in diabetes, obesity and atherosclerosis, as well as the use of this bacterium …
Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes.
Rodrigues VF, Elias-Oliveira J, Pereira ÍS, Pereira JA, Barbosa SC, Machado MSG, Carlos D. Rodrigues VF, et al. Front Immunol. 2022 Jul 7;13:934695. doi: 10.3389/fimmu.2022.934695. eCollection 2022. Front Immunol. 2022. PMID: 35874661 Free PMC article. Review.
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium that colonizes the intestinal mucosa of humans and rodents. ...Corroborating these human correlation data, it has been reported that A. muciniphila slows down the development and progressi …
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium that colonizes the intestinal mucosa of humans a …
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.
Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, Guiot Y, Derrien M, Muccioli GG, Delzenne NM, de Vos WM, Cani PD. Everard A, et al. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9066-71. doi: 10.1073/pnas.1219451110. Epub 2013 May 13. Proc Natl Acad Sci U S A. 2013. PMID: 23671105 Free PMC article.
Microbial composition and the mechanisms of interaction with the host that affect gut barrier function during obesity and type 2 diabetes have not been elucidated. We recently isolated Akkermansia muciniphila, which is a mucin-degrading bacterium that resides in the …
Microbial composition and the mechanisms of interaction with the host that affect gut barrier function during obesity and type 2 diab …
Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms.
Cani PD, Depommier C, Derrien M, Everard A, de Vos WM. Cani PD, et al. Nat Rev Gastroenterol Hepatol. 2022 Oct;19(10):625-637. doi: 10.1038/s41575-022-00631-9. Epub 2022 May 31. Nat Rev Gastroenterol Hepatol. 2022. PMID: 35641786 Review.
Ever since Akkermansia muciniphila was discovered and characterized two decades ago, numerous studies have shown that the lack or decreased abundance of this commensal bacterium was linked with multiple diseases (such as obesity, diabetes, liver steatosis, inflammat …
Ever since Akkermansia muciniphila was discovered and characterized two decades ago, numerous studies have shown that the lack or dec …
The human gut microbiota: Metabolism and perspective in obesity.
Gomes AC, Hoffmann C, Mota JF. Gomes AC, et al. Gut Microbes. 2018 Jul 4;9(4):308-325. doi: 10.1080/19490976.2018.1465157. Epub 2018 May 24. Gut Microbes. 2018. PMID: 29667480 Free PMC article. Review.
The gut microbiota has been recognized as an important factor in the development of metabolic diseases such as obesity and is considered an endocrine organ involved in the maintenance of energy homeostasis and host immunity. ...Furthermore, intestinal dysbiosis can alter t …
The gut microbiota has been recognized as an important factor in the development of metabolic diseases such as obesity and is conside …
A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KC, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD. Plovier H, et al. Nat Med. 2017 Jan;23(1):107-113. doi: 10.1038/nm.4236. Epub 2016 Nov 28. Nat Med. 2017. PMID: 27892954 Free article. Clinical Trial.
Obesity and type 2 diabetes are associated with low-grade inflammation and specific changes in gut microbiota composition. We previously demonstrated that administration of Akkermansia muciniphila to mice prevents the development of obesity and associated com …
Obesity and type 2 diabetes are associated with low-grade inflammation and specific changes in gut microbiota composition. We previou …
Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.
Depommier C, Everard A, Druart C, Plovier H, Van Hul M, Vieira-Silva S, Falony G, Raes J, Maiter D, Delzenne NM, de Barsy M, Loumaye A, Hermans MP, Thissen JP, de Vos WM, Cani PD. Depommier C, et al. Nat Med. 2019 Jul;25(7):1096-1103. doi: 10.1038/s41591-019-0495-2. Epub 2019 Jul 1. Nat Med. 2019. PMID: 31263284 Free PMC article. Clinical Trial.
The gut microbiota is a new key contributor involved in the onset of obesity-related disorders(2). In humans, studies have provided evidence for a negative correlation between Akkermansia muciniphila abundance and overweight, obesity, untreated type 2 diabete …
The gut microbiota is a new key contributor involved in the onset of obesity-related disorders(2). In humans, studies have provided e …
Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology.
Dao MC, Everard A, Aron-Wisnewsky J, Sokolovska N, Prifti E, Verger EO, Kayser BD, Levenez F, Chilloux J, Hoyles L; MICRO-Obes Consortium; Dumas ME, Rizkalla SW, Doré J, Cani PD, Clément K. Dao MC, et al. Gut. 2016 Mar;65(3):426-36. doi: 10.1136/gutjnl-2014-308778. Epub 2015 Jun 22. Gut. 2016. PMID: 26100928 Free article. Clinical Trial.
OBJECTIVE: Individuals with obesity and type 2 diabetes differ from lean and healthy individuals in their abundance of certain gut microbial species and microbial gene richness. Abundance of Akkermansia muciniphila, a mucin-degrading bacterium, has been inversely as …
OBJECTIVE: Individuals with obesity and type 2 diabetes differ from lean and healthy individuals in their abundance of certain gut mi …
Function of Akkermansia muciniphila in Obesity: Interactions With Lipid Metabolism, Immune Response and Gut Systems.
Xu Y, Wang N, Tan HY, Li S, Zhang C, Feng Y. Xu Y, et al. Front Microbiol. 2020 Feb 21;11:219. doi: 10.3389/fmicb.2020.00219. eCollection 2020. Front Microbiol. 2020. PMID: 32153527 Free PMC article. Review.
Obesity and its metabolic syndrome, including liver disorders and type 2 diabetes, are a worldwide epidemic and are intimately linked to diet. ...A. muciniphila is consistently correlated with obesity. The causal beneficial impact of A. muciniphila treatment on o …
Obesity and its metabolic syndrome, including liver disorders and type 2 diabetes, are a worldwide epidemic and are intimately linked …
Profile of the gut microbiota of adults with obesity: a systematic review.
Crovesy L, Masterson D, Rosado EL. Crovesy L, et al. Eur J Clin Nutr. 2020 Sep;74(9):1251-1262. doi: 10.1038/s41430-020-0607-6. Epub 2020 Mar 30. Eur J Clin Nutr. 2020. PMID: 32231226 Review.
Recently, relationship between gut microbiota composition and development of obesity has been pointed. However, the gut microbiota composition of individual with obesity is not known yet. ...These results may help in advances of the diagnosis and treatment of obe …
Recently, relationship between gut microbiota composition and development of obesity has been pointed. However, the gut microbiota co …
762 results