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Treatment of Wegener's granulomatosis with intermittent high-dose intravenous cyclophosphamide.
Hoffman GS, Leavitt RY, Fleisher TA, Minor JR, Fauci AS. Hoffman GS, et al. Among authors: leavitt ry. Am J Med. 1990 Oct;89(4):403-10. doi: 10.1016/0002-9343(90)90367-m. Am J Med. 1990. PMID: 2220874
This study sought to determine the efficacy, toxicity, and immunologic effects of glucocorticoids (GC) and intermittent high-dose intravenous CP ("pulse" CP) in the treatment of 14 patients with Wegener's granulomatosis (WG). ...These observations indi …
This study sought to determine the efficacy, toxicity, and immunologic effects of glucocorticoids (GC) and intermittent high-dose
Wegener granulomatosis: an analysis of 158 patients.
Hoffman GS, Kerr GS, Leavitt RY, Hallahan CW, Lebovics RS, Travis WD, Rottem M, Fauci AS. Hoffman GS, et al. Among authors: leavitt ry. Ann Intern Med. 1992 Mar 15;116(6):488-98. doi: 10.7326/0003-4819-116-6-488. Ann Intern Med. 1992. PMID: 1739240
One hundred and thirty-three patients (84%) received "standard" therapy with daily low-dose cyclophosphamide and glucocorticoids. Eight (5.0%) received only low-dose cyclophosphamide. ...CONCLUSIONS: The course of Wegener granulomatosis has been …
One hundred and thirty-three patients (84%) received "standard" therapy with daily low-dose cyclophosphamide and glucocorticoi …