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Page 1
Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.
Nucleic Acids Res. 2012 Nov;40(21):10596-613. doi: 10.1093/nar/gks863. Epub 2012 Sep 21.
Nucleic Acids Res. 2012.
PMID: 23002135
Free PMC article.
Review.
Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.
Chen H, Kazemier HG, de Groote ML, Ruiters MH, Xu GL, Rots MG.
Chen H, et al. Among authors: de groote ml.
Nucleic Acids Res. 2014 Feb;42(3):1563-74. doi: 10.1093/nar/gkt1019. Epub 2013 Nov 4.
Nucleic Acids Res. 2014.
PMID: 24194590
Free PMC article.
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Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer.
van der Gun BT, de Groote ML, Kazemier HG, Arendzen AJ, Terpstra P, Ruiters MH, McLaughlin PM, Rots MG.
van der Gun BT, et al. Among authors: de groote ml.
Br J Cancer. 2011 Jul 12;105(2):312-9. doi: 10.1038/bjc.2011.231. Epub 2011 Jun 21.
Br J Cancer. 2011.
PMID: 21694727
Free PMC article.
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A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.
Brink MC, Piebes DG, de Groote ML, Luijsterburg MS, Casas-Delucchi CS, van Driel R, Rots MG, Cardoso MC, Verschure PJ.
Brink MC, et al. Among authors: de groote ml.
PLoS One. 2013 Jul 23;8(7):e69347. doi: 10.1371/journal.pone.0069347. Print 2013.
PLoS One. 2013.
PMID: 23935992
Free PMC article.
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Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.
Niessen RC, Hofstra RM, Westers H, Ligtenberg MJ, Kooi K, Jager PO, de Groote ML, Dijkhuizen T, Olderode-Berends MJ, Hollema H, Kleibeuker JH, Sijmons RH.
Niessen RC, et al. Among authors: de groote ml.
Genes Chromosomes Cancer. 2009 Aug;48(8):737-44. doi: 10.1002/gcc.20678.
Genes Chromosomes Cancer. 2009.
PMID: 19455606
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Upregulation of endogenous ICAM-1 reduces ovarian cancer cell growth in the absence of immune cells.
de Groote ML, Kazemier HG, Huisman C, van der Gun BT, Faas MM, Rots MG.
de Groote ML, et al.
Int J Cancer. 2014 Jan 15;134(2):280-90. doi: 10.1002/ijc.28375. Epub 2013 Aug 10.
Int J Cancer. 2014.
PMID: 23832872
Free article.
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