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Curr Biol. 2002 Jan 22;12(2):R59-61.

Transcriptional control: an activating role for arginine methylation.

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  • 1Department of Biochemistry and Molecular Biology, U.T. M.D. Anderson Cancer Center, Houston, Texas 77030, USA.


A rare histone modification, arginine methylation, has been linked to activation of hormone-responsive genes. Interestingly, methylation of a lysine residue in the same histone is present prior to hormone activation, but is excluded from the active loci.

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