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| Year | Number of Results |
|---|---|
| 2007 | 1 |
| 2009 | 1 |
| 2010 | 4 |
| 2013 | 1 |
| 2014 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2021 | 1 |
| 2024 | 0 |
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Curcumin suppresses tumor growth of gemcitabine-resistant non-small cell lung cancer by regulating lncRNA-MEG3 and PTEN signaling.
Clin Transl Oncol. 2021 Jul;23(7):1386-1393. doi: 10.1007/s12094-020-02531-3. Epub 2021 Feb 10.
Clin Transl Oncol. 2021.
PMID: 33566305
However, whether curcumin can inhibit gemcitabine-resistant non-small cell lung cancer through regulation of lncRNA and the involved molecular mechanisms are rarely reported. ...CONCLUSIONS: These findings show the antitumor activity of curcumin …
However, whether curcumin can inhibit gemcitabine-resistant non-small cell lung cancer through regulation of lncRNA and the in …
Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.
Cancer Res. 2007 Apr 15;67(8):3853-61. doi: 10.1158/0008-5472.CAN-06-4257.
Cancer Res. 2007.
PMID: 17440100
In this study, we investigated whether curcumin can sensitize pancreatic cancer to gemcitabine in vitro and in vivo. In vitro, curcumin inhibited the proliferation of various pancreatic cancer cell lines, potentiated the apoptosis induced by gemcita …
In this study, we investigated whether curcumin can sensitize pancreatic cancer to gemcitabine in vitro and in vivo. In vitro, …
Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers.
Biochem Pharmacol. 2010 Jan 15;79(2):218-28. doi: 10.1016/j.bcp.2009.08.007. Epub 2009 Aug 12.
Biochem Pharmacol. 2010.
PMID: 19682434
Free PMC article.
Retracted.
Curcumin potentiated the apoptotic effects of gemcitabine against human bladder cancer 253JBV cells in culture. Electrophoretic mobility shift assay revealed that curcumin also suppressed the gemcitabine-induced activation of the cell sur …
Curcumin potentiated the apoptotic effects of gemcitabine against human bladder cancer 253JBV cells in culture. Electro …
Therapeutic Potential of Curcumin in Treatment of Pancreatic Cancer: Current Status and Future Perspectives.
J Cell Biochem. 2017 Jul;118(7):1634-1638. doi: 10.1002/jcb.25897. Epub 2017 Mar 15.
J Cell Biochem. 2017.
PMID: 28106283
Review.
The antitumor activity of curcumin in several tumors, including prostate, breast and colorectal cancers have investigated. ...Another trial showed the activity of 8,000 mg of curcumin in combination with gemcitabine in patients with advan …
The antitumor activity of curcumin in several tumors, including prostate, breast and colorectal cancers have investigat …
Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications.
Curr Med Chem. 2010;17(3):190-7. doi: 10.2174/092986710790149738.
Curr Med Chem. 2010.
PMID: 20214562
Review.
Our clinical experience with curcumin, along with the anti-metabolite gemcitabine in the treatment of patients with advanced pancreatic carcinoma, produced an objective response in less than 10% of patients, with a minor effect on survival. However, the safety of th …
Our clinical experience with curcumin, along with the anti-metabolite gemcitabine in the treatment of patients with advanced p …
Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF.
Cancer Res. 2010 May 1;70(9):3606-17. doi: 10.1158/0008-5472.CAN-09-4598. Epub 2010 Apr 13.
Cancer Res. 2010.
PMID: 20388782
Free PMC article.
Retracted.
Curcumin induces cancer cell growth arrest and apoptosis in vitro, but its poor bioavailability in vivo limits its antitumor efficacy. ...In this study, we evaluated the effects of CDF or curcumin alone or in combination with gemcitabine on cell viabil …
Curcumin induces cancer cell growth arrest and apoptosis in vitro, but its poor bioavailability in vivo limits its antitumor e …
Curcumin and gemcitabine in patients with advanced pancreatic cancer.
Nutr Cancer. 2010;62(8):1137-41. doi: 10.1080/01635581.2010.513802.
Nutr Cancer. 2010.
PMID: 21058202
Clinical Trial.
Curcumin has a potent antiproliferative activity and can also potentiate the antitumor effect of gemcitabine. This study was undertaken to evaluate the activity and feasibility of gemcitabine in combination with curcumin in …
Curcumin has a potent antiproliferative activity and can also potentiate the antitumor effect of gemcitabine …
Curcumin induces apoptosis and inhibits growth of orthotopic human non-small cell lung cancer xenografts.
J Nutr Biochem. 2014 Aug;25(8):843-50. doi: 10.1016/j.jnutbio.2014.03.014. Epub 2014 Apr 13.
J Nutr Biochem. 2014.
PMID: 24835302
H1975 NSCLC cells were treated with curcumin (0-50 muM) alone, or combined with gemcitabine or cisplatin. ...Western blot analysis showed that the expressions of IkB, nuclear p65, cyclooxygenase 2 (COX-2) and p-ERK1/2 were down-regulated by curcumin in vitro. …
H1975 NSCLC cells were treated with curcumin (0-50 muM) alone, or combined with gemcitabine or cisplatin. ...Western blot anal …
Curcumin inhibits tumor growth and angiogenesis in an orthotopic mouse model of human pancreatic cancer.
Biomed Res Int. 2013;2013:810423. doi: 10.1155/2013/810423. Epub 2013 Nov 10.
Biomed Res Int. 2013.
PMID: 24324975
Free PMC article.
In this study, we investigated whether curcumin plays antitumor effects in MIA PaCa-2 cells. In vitro studies showed that curcumin inhibits the proliferation and enhances apoptosis of MIA PaCa-2 cells. To test whether the antitumor activity of …
In this study, we investigated whether curcumin plays antitumor effects in MIA PaCa-2 cells. In vitro studies showed that c …
Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas.
Cancers (Basel). 2018 Mar 22;10(4):89. doi: 10.3390/cancers10040089.
Cancers (Basel). 2018.
PMID: 29565326
Free PMC article.
However, a major challenge is to maximize EBV lytic reactivation by CLVA. Curcumin, a dietary spice used in Asian countries, is known for its antitumor property and therapeutic potential. Novel curcuminoids that were developed to increase efficacy and bioavai …
However, a major challenge is to maximize EBV lytic reactivation by CLVA. Curcumin, a dietary spice used in Asian countries, is known …
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